scholarly journals No Evidence of Infectious Retroviruses in Measles Virus Vaccines Produced in Chicken Embryo Cell Cultures

2001 ◽  
Vol 39 (2) ◽  
pp. 675-684 ◽  
Author(s):  
M. Shahabuddin ◽  
J. F. Sears ◽  
A. S. Khan
1977 ◽  
Vol 6 (6) ◽  
pp. 639-641
Author(s):  
D R Woodman ◽  
R Grays ◽  
E Weiss

The plaque technique for three strains of Rickettsia tsutsugamushi in chicken embryo cell cultures was greatly improved by modifying the trypsinizing procedure and employing homologous chicken serum in the overlay medium.


1976 ◽  
Vol 3 (3) ◽  
pp. 277-280
Author(s):  
S Marks-Hellman ◽  
M Ho

Fifty clinical isolates of Herpesvirus hominis were typed by pock size on chicken embryo chorioallantoic membranes, sensitivity to heparin, and plaque formation on chicken embryo cell cultures. Of 19 isolates that were typed serologically, there was 100% concordance with respect to plaque formation. Pock size was incorrect in one instance and indeterminate in another. Heparin sensitivity was incorrect for one. Of 31 strains that were only biologically characterized, there were four for which heparin sensitivity did not agree with the other two characteristics. Of the three biological tests, the ability to form plaques in chick cell monolayer was the most reliable indicator type.


The Lancet ◽  
1983 ◽  
Vol 321 (8326) ◽  
pp. 700 ◽  
Author(s):  
R Barth ◽  
U Bijok ◽  
H Gruschkau ◽  
J Smerdel ◽  
J Vodopija

1988 ◽  
Vol 24 (11) ◽  
pp. 1061-1062 ◽  
Author(s):  
Réjean Morais ◽  
Karen Zinkewich-Péotti ◽  
Paul Desjardins ◽  
Claude-Lise Richer

1975 ◽  
Vol 2 (4) ◽  
pp. 300-304
Author(s):  
R H Kenyon ◽  
L S Sammons ◽  
C E Pedersen

Growth of Rocky Mountain spotted fever (RMSF) rickettsiae in duck embryo cell (DEC) cultures and chicken embryo cell (CEC) cultures was evaluated. Experimental lots of duck embryo cell- and chicken embryo cell-grown Rocky Mountain spotted fever vaccines and a commercial lot of yolk sac-grown vaccine were compared for protective efficacy in rhesus monkeys. Incidence and magnitude of antibody response, febrile response, and rickettsemia, as well as incidence of fatalities, suggested that both cell culture-derived vaccines were more immunogenic than the yolk sac-grown vaccine.


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