scholarly journals ESAT-6/CFP-10 Fusion Protein and Peptides for Optimal Diagnosis of Mycobacterium tuberculosis Infection by Ex Vivo Enzyme-Linked Immunospot Assay in The Gambia

2005 ◽  
Vol 43 (5) ◽  
pp. 2070-2074 ◽  
Author(s):  
P. C. Hill ◽  
D. Jackson-Sillah ◽  
A. Fox ◽  
K. L. M. C. Franken ◽  
M. D. Lugos ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Fusion Protein ◽  
Ex Vivo ◽  
The Gambia ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6

Vaccine ◽  
2005 ◽  
Vol 23 (21) ◽  
pp. 2740-2750 ◽  
Author(s):  
Jan A.M. Langermans ◽  
T. Mark Doherty ◽  
Richard A.W. Vervenne ◽  
Tridia van der Laan ◽  
Konstantin Lyashchenko ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Fusion Protein ◽  
Subunit Vaccine ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Antigen 85B ◽  
A Subunit

scholarly journals Erratum for Araujo et al., Evaluation of Gamma Interferon Immune Response Elicited by the Newly Constructed PstS-1(285-374):CFP10 Fusion Protein To Detect Mycobacterium tuberculosis Infection

2014 ◽  
Vol 21 (11) ◽  
pp. 1600-1600
Author(s):  
Leonardo Silva de Araujo ◽  
Fernanda Carvalho de Queiroz Mello ◽  
Nidai de Bárbara Moreira da Silva ◽  
Janaina Aparecida Medeiros Leung ◽  
Silvia Maria Almeida Machado ◽  
...  
Keyword(s):  
Immune Response ◽  
Mycobacterium Tuberculosis ◽  
Fusion Protein ◽  
Gamma Interferon ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

scholarly journals Nanoparticle-Fusion Protein Complexes Protect against Mycobacterium tuberculosis Infection

2018 ◽  
Vol 26 (3) ◽  
pp. 822-833 ◽  
Author(s):  
Peter Hart ◽  
Alastair Copland ◽  
Gil Reynolds Diogo ◽  
Shane Harris ◽  
Ralf Spallek ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Fusion Protein ◽  
Protein Complexes ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection

scholarly journals Abnormal spontaneous interleukin 8 receptor expression: a brief report of two cases

2012 ◽  
Vol 45 (1) ◽  
pp. 134-137 ◽  
Author(s):  
Paulo Antas ◽  
Steven Holland ◽  
Timothy Sterling
Keyword(s):  
Mycobacterium Tuberculosis ◽  
T Lymphocytes ◽  
Ex Vivo ◽  
Receptor Expression ◽  
Interleukin 8 ◽  
Tuberculosis Infection ◽  
Mycobacterium Tuberculosis Infection ◽  
Purified Protein Derivative ◽  
Spontaneous Expression

Interleukin 8 (CXCL8) is an autocrine chemokine specific for the chemoattraction and activation of granulocytes, NKT cells and T lymphocytes. Patients with tuberculosis and latent Mycobacterium tuberculosis infection were assessed for the spontaneous expression of CXCR1 (CD128) and CXCR2 on lymphocytes and monocytes. Compared with ex vivo profiles, increased spontaneous CXCR2 expression and normal CXCR1 expression were found on lymphocytes in two out of 59 individuals. Monocytes showed normal ex vivo profiles for both receptors. After stimulation with purified protein derivative, the in vitro levels of CXCL8 were below the median levels of all patients with prior tuberculosis. Spontaneous CXCR2 modulation did not cause notable variation in the in vitro levels of CXCL8.

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