Peptides Corresponding to the Heptad Repeat Motifs in the Transmembrane Protein (gp41) of Human Immunodeficiency Virus Type 1 Elicit Antibodies to Receptor-Activated Conformations of the Envelope Glycoprotein
2001 ◽
Vol 75
(18)
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pp. 8859-8863
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Keyword(s):
Hiv 1
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ABSTRACT Two heptad repeat regions in the ectodomain of the human immunodeficiency virus type 1 (HIV-1) transmembrane subunit (gp41) self-assemble into a six-helix bundle structure that is critical for virus entry. Immunizations with peptides corresponding to these regions generated antibodies specific to the receptor-activated conformations of gp41.
2000 ◽
Vol 74
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pp. 5368-5372
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1993 ◽
Vol 191
(1)
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pp. 207-213
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2000 ◽
Vol 74
(18)
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pp. 8358-8367
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2002 ◽
Vol 76
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pp. 6780-6790
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1992 ◽
Vol 73
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pp. 951-954
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1998 ◽
Vol 72
(2)
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pp. 986-993
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