scholarly journals Congenital duodenal obstruction in the UK: a population-based study

2019 ◽  
Vol 105 (2) ◽  
pp. 178-183 ◽  
Author(s):  
George Stephen Bethell ◽  
Anna-May Long ◽  
Marian Knight ◽  
Nigel J Hall
Keyword(s):  
Duodenal Obstruction ◽  
Population Based ◽  
Small Sample ◽  
Associated Anomalies ◽  
Short Term ◽  
Population Based Study ◽  
Congenital Duodenal Obstruction ◽  
Operation Rate ◽  
The Uk ◽  
Postoperative Feeding

ObjectiveCongenital duodenal obstruction (CDO) comprising duodenal atresia or stenosis is a rare congenital anomaly requiring surgical correction in early life. Identification of variation in surgical and postoperative practice in previous studies has been limited by small sample sizes. This study aimed to prospectively estimate the incidence of CDO in the UK, and report current management strategies and short-term outcomes.DesignProspective population-based, observational study for 12 months from March 2016.SettingSpecialist neonatal surgical units in the UK.Main outcome measuresIncidence of CDO, associated anomalies and short-term outcomes.ResultsIn total, 110 cases were identified and data forms were returned for 103 infants giving an estimated incidence of 1.22 cases per 10 000 (95% CI 1.01 to 1.49) live births. Overall, 59% of cases were suspected antenatally and associated anomalies were seen in 69%. Operative repair was carried out mostly by duodenoduodenostomy (76%) followed by duodenojejunostomy (15%). Postoperative feeding practice varied with 42% having a trans-anastomotic tube placed and 88% receiving parenteral nutrition. Re-operation rate related to the initial procedure was 3% within 28 days. Two infants died within 28 days of operation from unrelated causes.ConclusionThis population-based study of CDO has shown that the majority of infants have associated anomalies. There is variation in postoperative feeding strategies which represent opportunities to explore the effects of these on outcome and potentially standardise approach. Short-term outcomes are generally good.

scholarly journals The haematological features and transfusion management of women who required massive transfusion for major obstetric haemorrhage in the UK: a population based study

2015 ◽  
Vol 172 (4) ◽  
pp. 616-624 ◽  
Author(s):  
Laura Green ◽  
Marian Knight ◽  
Frances Seeney ◽  
Cathy Hopkinson ◽  
Peter W. Collins ◽  
...  
Keyword(s):  
Massive Transfusion ◽  
Population Based ◽  
Population Based Study ◽  
Obstetric Haemorrhage ◽  
The Uk

scholarly journals Short-Term Outcomes Following Minimally Invasive and Open Esophagectomy: A Population-Based Study from Finland and Sweden

2017 ◽  
Vol 25 (1) ◽  
pp. 326-332 ◽  
Author(s):  
Joonas H. Kauppila ◽  
Olli Helminen ◽  
Ville Kytö ◽  
Jarmo Gunn ◽  
Jesper Lagergren ◽  
...  
Keyword(s):  
Minimally Invasive ◽  
Population Based ◽  
Short Term ◽  
Population Based Study ◽  
Open Esophagectomy

Congenital Duodenal Obstruction: Evaluation of 68 Cases

2021 ◽  
Author(s):  
Emel Çolak ◽  
Ayşenur Celayir
Keyword(s):  
Duodenal Obstruction ◽  
Associated Anomalies ◽  
Hospital Records ◽  
Cardiac Malformations ◽  
Congenital Duodenal Obstruction ◽  
Clinical Presentations ◽  
Hospitalization Period ◽  
Common Causes ◽  
The Mean ◽  
Associated Abnormalities

INTRODUCTION: Congenital duodenal obstruction, which is one of the most common causes of intestinal obstruction in neonates, gain importance in terms of associated anomalies. In this study, we aimed to review our experience with congenital duodenal obstruction cases operated in our clinic while evaluating the results of these patients. METHODS: All hospital records of neonates with congenital duodenal obstruction which had operated in our department between 2004 and 2017 were reviewed retrospectively. Patients were evaluated according to their demographic features, clinical presentations, associated anomalies, treatments and outcomes. RESULTS: During 13 years, 68 newborns (36 males, 32 females) with congenital duodenal obstruction were operated. The mean gestational age was 35.7±3.1weeks (28-44weeks), the mean birth weight was 2477±651.5 gram (1100–4100 gram) and 46 (67.7%) of them were premature. Associated abnormalities were detected in 37 neonates (54.4%); 16 of them (23.5%) had congenital cardiac malformations, and 13 of them (19.1%) had Down Syndrome. In neonates with associated abnormalities; the avarage period to start enteral feeding was 9.5±5.8 days (4-37days) and the mean hospitalization period was 25.6±26.2days (9-140days). These values were found 7.6±3.2 days (4-20days) and 17.5±13.7days (8-80days) respectively for the patients having no associated anomalies. Postoperative complications such as ileus, septicemia and nutritional intolerance were seen in 17 patients (25%); 3 of them (4.4%) need re-operation. While 63 patients (92.6%) were discharged on average 21.4±22 days (8-140 days); due to septicemia and severe congenital cardiac malformations 5 patients (7.4%) were died in 27.2±14.1 days (11-43days) postoperatively. The rate of septicemia was statistically significantly higher in patients with excitus than the ones who were discharged (p<0.001). DISCUSSION AND CONCLUSION: The presence of associated abnormalities in patients with congenital duodenal obstruction increases the risk of morbidity and mortality. Septicemia and severe congenital cardiac malformations adversely affect prognosis.

scholarly journals Characterizing Short-Term Jobs in a Population-Based Study

2019 ◽  
Vol 63 (6) ◽  
pp. 701-705 ◽  
Author(s):  
Marie-Élise Parent ◽  
Hugues Richard ◽  
Jean-François Sauvé
Keyword(s):  
Exposure Assessment ◽  
Population Based ◽  
Short Term ◽  
Population Based Study ◽  
Outdoor Work ◽  
Disease Aetiology ◽  
Lifetime Exposure ◽  
Poor Ventilation ◽  
Work Histories ◽  
Control Study

Abstract Background Work histories generally cover all jobs held for ≥1 year. However, it may be time and cost prohibitive to conduct a detailed exposure assessment for each such job. While disregarding short-term jobs can reduce the assessment burden, this can be problematic if those jobs contribute important exposure information towards understanding disease aetiology. Objective To characterize short-term jobs, defined as lasting more than 1 year, but less than 2 years, in a population-based study conducted in Montreal, Canada. Methods In 2005–2012, we collected work histories for some 4000 participants in a case-control study of prostate cancer. Overall, subjects had held 19 462 paid jobs lasting ≥1 year, including 3655 short-term jobs. Using information from interviews and from the Canadian Classification and Dictionary of Occupations, we characterized short-term jobs and compared them to jobs held ≥2 years. Results Short-term jobs represented <4% of subjects’ work years on average. Forty-five per cent of subjects had at least one short-term job; of these, 49% had one, 24% had two, and 27% had at least three. Half of all short-term jobs had been held before the age of 24. Short-term jobs entailed more often exposure to fumes, odours, dust, and/or poor ventilation than longer jobs (17 versus 13%), as well as outdoor work (10 versus 5%) and heavy physical activity (16 versus 12%). Conclusions Short-term jobs occurred often in early careers and more frequently entailed potentially hazardous exposures than longer-held jobs. However, as they represented a small proportion of work years, excluding them should have a marginal impact on lifetime exposure assessment.

Dandy-Walker Syndrome, Associated Anomalies and Survival through Infancy: A Population-Based Study

2008 ◽  
Vol 24 (2) ◽  
pp. 155-160 ◽  
Author(s):  
Hamisu M. Salihu ◽  
Jennifer L. Kornosky ◽  
Charlotte M. Druschel
Keyword(s):  
Population Based ◽  
Associated Anomalies ◽  
Population Based Study
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