G235(P) Isolated fetal hydronephrosis: sonographic predictors of adverse postnatal outcome

Abstract Purpose Parents confronted with the finding of antenatal hydronephrosis (ANH) are particularly interested in whether their baby will need postnatal surgery. The objective of this study was to predict ANH requiring surgery on the basis of the fetal anteroposterior renal pelvic diameter (APRPD) and the Society for Fetal Urology (SFU) grading system. Materials and Methods The medical records of 179 patients with the finding of ANH were reviewed retrospectively. ANH was graded according to the SFU grading system. Prenatal ultrasound examinations were correlated to postnatal outcome, which was divided into three groups: prenatal resolution, conservative management and surgical treatment. Results 58 (32.4 %) cases were classified as prenatal resolution, 89 (49.7 %) babies were assigned to the conservative outcome group and 32 (17.9 %) patients needed surgical repair. Postnatal surgery was best predicted in the second trimester (area under the receiver operating characteristics curve: 0.839) by an APRPD cut-off of 8.3 mm (sensitivity: 77.8 %; specificity: 85.7 %; PPV of 53.9 %, NPV of 94.7 %). The combination of the parameters “progression of SFU grade” and SFU grade 3 or 4 achieved a sensitivity of 84.4 % and a specificity of 80.3 % for the prediction of surgery. Conclusion Second-trimester APRPD is a useful parameter for predicting the risk for postnatal surgery. The SFU grade should be assessed in every prenatal ultrasound examination as some further risk estimates can be made based on its dynamics over time.

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Ultrasound diagnosis of fetal hydronephrosis: fetal renal pelvic size correlated to postnatal outcome

Pediatric Surgery International ◽

10.1007/bf00181848 ◽

1989 ◽

Vol 4 (2) ◽

Author(s):

Connie J�rgensen ◽

Carl-Magnus Kullendorff

Keyword(s):

Ultrasound Diagnosis ◽

Fetal Hydronephrosis ◽

Postnatal Outcome ◽

Pelvic Size

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Severe fetal hydronephrosis: the added value of associated congenital anomalies of the kidneys and urinary tract (CAKUT) in the prediction of postnatal outcome

Prenatal Diagnosis ◽

10.1002/pd.5206 ◽

2018 ◽

Vol 38 (3) ◽

pp. 179-183 ◽

Cited By ~ 2

Author(s):

Sharon Perlman ◽

Lucia Roitman ◽

Danny Lotan ◽

Zvi Kivilevitch ◽

Naomi Pode-Shakked ◽

...

Keyword(s):

Urinary Tract ◽

Congenital Anomalies ◽

Added Value ◽

Fetal Hydronephrosis ◽

Postnatal Outcome

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Prenatal diagnosis and postnatal outcome of fetuses with double outlet right ventricle (DORV) in a single center

10.1055/s-0038-1670413 ◽

2018 ◽

Author(s):

I Gottschalk

Keyword(s):

Prenatal Diagnosis ◽

Right Ventricle ◽

Double Outlet Right Ventricle ◽

Single Center ◽

Postnatal Outcome

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Ultrasound screening and catamnesis of euploid fetuses with nasal bones aplasia/hypoplasia

10.21516/2413-1458-2017-16-1-22-31 ◽

2017 ◽

Author(s):

N.P. Veropotvelyan, A.A. Bondarenko

Keyword(s):

Chromosomal Abnormalities ◽

Nasal Bone ◽

Normal Karyotype ◽

Psychomotor Development ◽

Ultrasound Screening ◽

Normal Height ◽

Term Infants ◽

Nasal Bones ◽

Postnatal Outcome ◽

Selection Of

Objective. To evaluate the pre- and postnatal outcomes of euploid fetuses with aplasia/hypoplasia of the nasal bones (NB). Methods. We have made the catamnestic monitoring of children with a normal karyotype, who had been prenatally detected NB aplasia or hypoplasia (less than 5 perentile) at 11–24 weeks of gestation at ultrasound screening in the period between 2006–2015 years. Our study included a selection of 242 fetuses with NB aplasia or hypoplasia, in 128 (52.8 %) of them the NB was not visualized or appeared as an echogenic dot only. Results. Among all 63 fetuses with NB aplasia (absence or looks as an echogenic dot) in the 1st trimester in 24 (38 %) cases chromosomal abnormalities (CA) were found (including T21 — 15 (62.5 %) cases). Other 39 (61.9 %) fetuses had a normal karyotype. Among 65 fetuses with NB aplasia, examined in the 2nd trimester of gestation 12 (18.4 %) cases of CA were detected (one fetus with T21 had the only one ultrasound marker – isolated NB aplasia), 53 (81.5 %) fetuses had a normal karyotype. 62 mothers of the euploid fetuses with NB aplasia had been surveyed. We have received and analyzed 31 (50 %) responses. In 16 cases of euploid fetuses with NB, aplasia pregnancy outcome was adverse or relatively unfavorable, only 5 (31.2 %) fetuses of them had isolated NB aplasia. In other cases healthy full-term infants were born, who showed normal height and weight indexes, physical and psychomotor development observed in age from 0 to 10. Conclusion. In 51.6 % fetuses and children prenatally had aplasia of the nasal bone was marked by unfavorable pre- or postnatal outcome, according to the survey of their mothers.

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