scholarly journals Intracerebral haemorrhage, anticoagulation and mechanical heart valves: what should I do next?

2013 ◽  
Vol 2013 (jun26 1) ◽  
pp. bcr2013008639-bcr2013008639
Author(s):  
R. Shah ◽  
D. Shah ◽  
S. Koganti ◽  
R. Davies
Keyword(s):  
Intracerebral Haemorrhage ◽  
Heart Valves ◽  
Mechanical Heart Valves

scholarly journals Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves

2018 ◽  
Vol 39 (19) ◽  
pp. 1709-1723 ◽  
Author(s):  
Joji B Kuramatsu ◽  
Jochen A Sembill ◽  
Stefan T Gerner ◽  
Maximilian I Sprügel ◽  
Manuel Hagen ◽  
...  
Keyword(s):  
Intracerebral Haemorrhage ◽  
Heart Valves ◽  
Mechanical Heart Valves ◽  
Therapeutic Anticoagulation

scholarly journals When and in which patients can anticoagulation be resumed after intracerebral haemorrhage?

2011 ◽  
Vol 2 (1S) ◽  
pp. 115
Author(s):  
Marco Marietta ◽  
Paola Pedrazzi ◽  
Alessandro Ghiddi
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Trials ◽  
Intracerebral Haemorrhage ◽  
Heart Valves ◽  
Case Reports ◽  
Treatment Options ◽  
Major Haemorrhage ◽  
Mechanical Heart Valves ◽  
Antiaggregant Therapy

Whether to resume the anticoagulant or the antiaggregant therapy after an episode of major haemorrhage is a difficult dilemma for the physician. The physician has to take into consideration two major questions: whether the benefits of restarting anticoagulation outweigh the risk, and if so, when and how should anticoagulation be restarted. Although some case reports suggest that anticoagulation can be withheld safely for short periods after ICH, even in patients with mechanical heart valves, it is still not clear if long-term anticoagulation can be safely reinstituted after haemorrhage, for example in patients with atrial fibrillation. In fact, no large and well-conducted randomised clinical trials are available, and there is lack of strong evidence on which guidelines recommendations can be based. The article summarise the available literature findings. Finally, a protocol is suggested which may represent a useful tool for assessing treatment options.

scholarly journals When and in which patients can anticoagulation be resumed after intracerebral haemorrhage?

2011 ◽  
Vol 2 (1S) ◽  
pp. 115-120
Author(s):  
Marco Marietta ◽  
Paola Pedrazzi ◽  
Alessandro Ghiddi
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Trials ◽  
Intracerebral Haemorrhage ◽  
Heart Valves ◽  
Case Reports ◽  
Treatment Options ◽  
Major Haemorrhage ◽  
Mechanical Heart Valves ◽  
Antiaggregant Therapy

Whether to resume the anticoagulant or the antiaggregant therapy after an episode of major haemorrhage is a difficult dilemma for the physician. The physician has to take into consideration two major questions: whether the benefits of restarting anticoagulation outweigh the risk, and if so, when and how should anticoagulation be restarted. Although some case reports suggest that anticoagulation can be withheld safely for short periods after ICH, even in patients with mechanical heart valves, it is still not clear if long-term anticoagulation can be safely reinstituted after haemorrhage, for example in patients with atrial fibrillation. In fact, no large and well-conducted randomised clinical trials are available, and there is lack of strong evidence on which guidelines recommendations can be based. The article summarise the available literature findings. Finally, a protocol is suggested which may represent a useful tool for assessing treatment options.

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