scholarly journals Prostatic cyst in autosomal dominant polycystic kidney disease: unusual association

2019 ◽  
Vol 12 (4) ◽  
pp. e228617
Author(s):  
Vivek Sood ◽  
Navin Pattanashetti ◽  
Mohamed Bilal Azam ◽  
Raja Ramachandran
Keyword(s):  
Urinary Tract Infection ◽  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Recurrent Urinary Tract Infection ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Outflow Obstruction ◽  
Unusual Association ◽  
Autosomal Dominant Polycystic Kidney ◽  
Prostatic Cyst

Prostate cyst, as an extrarenal manifestation in patients with autosomal dominant polycystic kidney disease, although infrequent, nevertheless goes beyond tenuous concomitance and may rarely contribute to recurrent urinary tract infection or outflow obstruction and mostly remains asymptomatic. In this context, we report a case of incidentally detected, an asymptomatic prostatic cyst in a patient of autosomal dominant polycystic kidney disease.

scholarly journals Insights into cellular and molecular basis for urinary tract infection in autosomal-dominant polycystic kidney disease

2017 ◽  
Vol 313 (5) ◽  
pp. F1077-F1083 ◽  
Author(s):  
Chao Gao ◽  
Long Zhang ◽  
Ye Zhang ◽  
Darren P. Wallace ◽  
Reynold I. Lopez-Soler ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Polycystic Kidney Disease ◽  
Molecular Mechanisms ◽  
Autosomal Dominant ◽  
Immune Defense ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

Urinary tract infection (UTI) is a broad term referring to an infection of the kidneys, ureters, bladder, and/or urethra. Because of its prevalence, frequent recurrence, and rising resistance to antibiotics, UTI has become a challenge in clinical practice. Autosomal-dominant polycystic kidney disease (ADPKD) is the most common monogenic disorder of the kidney and is characterized by the growth of fluid-filled cysts in both kidneys. Progressive cystic enlargement, inflammation, and interstitial fibrosis result in nephron loss with subsequent decline in kidney function. ADPKD patients frequently develop UTI; however, the cellular and molecular mechanisms responsible for the high UTI incidence in ADPKD patients remain virtually unaddressed. Emerging evidence suggests that α-intercalated cells (α-ICs) of the collecting ducts function in the innate immune defense against UTI. α-ICs inhibit bacterial growth by acidifying urine and secreting neutrophil gelatinase-associated lipocalin (NGAL) that chelates siderophore-containing iron. It is necessary to determine, therefore, if ADPKD patients with recurrent UTI have a reduced number and/or impaired function of α-ICs. Identification of the underlying cellular and molecular mechanisms may lead to the development of novel strategies to reduce UTI in ADPKD.

scholarly journals Dialysis and a urinary tract infection in patients with autosomal dominant polycystic kidney disease

Health of Man ◽  
2017 ◽  
Vol 0 (2(61)) ◽  
pp. 62-65
Author(s):  
В. М. Лісовий ◽  
Н. М. Андон’єва ◽  
О. А. Гуц ◽  
М. Я. Дубовик ◽  
М. М. Поляков ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Tract Infection ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney

Prostatic cyst in a pediatric patient with autosomal dominant polycystic kidney disease

2021 ◽  
Vol 14 (2) ◽  
pp. e236237
Author(s):  
Marc Colaco ◽  
Glenn M Cannon ◽  
Michael L Moritz
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Pediatric Patient ◽  
Autosomal Dominant ◽  
Paediatric Population ◽  
Cystic Disease ◽  
Polycystic Kidney ◽  
Renal Cystic Disease ◽  
Autosomal Dominant Polycystic Kidney ◽  
Prostatic Cyst

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inheritable form of renal cystic disease and is associated with cysts in other organs. Prostatic cysts are rare though and have not been reported in the paediatric population. Reported is the presence of a prostatic cyst that was incidentally noted on routine sonogram in a 15 year old with ADPKD.

Refractory Ascites Due to Portal Hypertension in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patients Successfully Treated with Peritoneal Dialysis

2010 ◽  
Vol 30 (2) ◽  
pp. 151-155 ◽  
Author(s):  
Danxia Zheng ◽  
Li-Tao Cheng ◽  
Qing-Feng Han ◽  
Wei Zhao ◽  
Xuan Li ◽  
...  
Keyword(s):  
Peritoneal Dialysis ◽  
Portal Hypertension ◽  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Refractory Ascites ◽  
Polycystic Kidney ◽  
Outflow Obstruction ◽  
Polycystic Liver ◽  
Autosomal Dominant Polycystic Kidney

Refractory ascites is uncommon in autosomal dominant polycystic kidney disease (ADPKD) but it usually makes the patient physically and psychologically handicapped. Two uremic ADPKD patients in our hospital developed refractory ascites after 1 year on hemodialysis. The refractory ascites was due to portal hypertension, which was caused primarily by portal outflow obstruction due to the numerous enlarged cysts in the liver and secondarily by increased portal inflow. We attempted continuous ambulatory peritoneal dialysis (CAPD) to treat the 2 patients and obtained satisfactory results. Not only was the refractory ascites well controlled, but also the portal hypertension disappeared. Based on our experience, we think CAPD could serve as a very effective therapy to treat the refractory ascites of portal hypertension due to polycystic liver in uremic ADPKD patients.

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