Mumps infection with meningoencephalitis and cerebellitis

Diagnosis of epidemic parotitis (EP) in typical cases of the disease is not difficult, which is explained by the salivary gland involvement characteristic of this infection. It is known that in the pathological process of ES, in addition to salivary glands, pancreas, testicles, etc. can be involved. At the same time, different authors assess the possibility of their isolated involvement ambiguously: either pancreatitis or orchitis are the only manifestations of mumps infection, or involvement of salivary glands in the pathological process is a mandatory component of ES and, therefore, involvement of other glands cannot be isolated.

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Virus-Induced Hydrocephalus: Development of Aqueductal Stenosis in Hamsters after Mumps Infection

Science ◽

10.1126/science.157.3792.1066 ◽

1967 ◽

Vol 157 (3792) ◽

pp. 1066-1067 ◽

Cited By ~ 73

Author(s):

R. T. Johnson ◽

K. P. Johnson ◽

C. J. Edmonds

Keyword(s):

Aqueductal Stenosis ◽

Mumps Infection

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Complications of Mumps Infection, Islet-Cell Antibodies, and HLA

Immunobiology ◽

10.1016/s0171-2985(84)80005-4 ◽

1984 ◽

Vol 167 (4) ◽

pp. 338-344 ◽

Cited By ~ 4

Author(s):

Gertrud Mueller-Eckhardt ◽

T. Stief ◽

A. Otten ◽

K. Helmke ◽

W.R. Willems ◽

...

Keyword(s):

Islet Cell ◽

Islet Cell Antibodies ◽

Mumps Infection

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The epidemiology of mumps in the UK: a preliminary study of virus transmission, herd immunity and the potential impact of immunization

Epidemiology and Infection ◽

10.1017/s0950268800066875 ◽

1987 ◽

Vol 99 (1) ◽

pp. 65-84 ◽

Cited By ~ 46

Author(s):

R. M. Anderson ◽

J. A. Crombie ◽

B. T. Grenfell

Keyword(s):

Herd Immunity ◽

Virus Transmission ◽

Epidemiological Data ◽

Mumps Virus ◽

Mass Vaccination ◽

Vaccine Uptake ◽

Published Data ◽

Epidemic Period ◽

Potential Impact ◽

Mumps Infection

SUMMARYMathematical models and statistical analyses of epidemiological data are employed to assess the potential impact of mass vaccination on the incidences of cases of mumps infection and cases of mumps related complications. The analyses reveal that in the United Kingdom the average age at infection with the mumps virus is currently between 6–7 years and that the inter-epidemic period of the infection is approximately 3 years. The critical level of vaccine uptake to eliminate mumps virus transmission is predicted to be approximately 85% of each cohort of boys and girls by the age of 2 years. Analyses of published data show that the risk of complication arising from mumps infection is markedly age- and sex-related. Model predictions suggest that the incidence of orchitis will be increased, over the level pertaining prior to mass vaccination, by levels of vaccine uptake (by 2 years of age) that are less than 70% of each yearly cohort of boys and girls. Moderate (over 00%) to high (75%) levels of vaccine uptake, however, are predicted to reduce the overall incidence of cases of mumps related complications (especially those with CNS involvement).

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