scholarly journals Low-salt Diet for Congestive Heart Failure

BMJ ◽  
1951 ◽  
Vol 1 (4719) ◽  
pp. 1349-1353
Author(s):  
A. L. Nielsen ◽  
P. Bechgaard ◽  
H. O. Bang
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Salt Diet ◽  
Low Salt

scholarly journals Acute and chronic hemodynamic effects of the basic therapeutic regimen for congestive heart failure. diuretics, low salt diet and bed rest.

1984 ◽  
Vol 25 (4) ◽  
pp. 571-585 ◽  
Author(s):  
Hirotaka NISHIJIMA ◽  
Hisakazu YASUDA ◽  
Kazusuke ITO ◽  
Rinji MURAKAMI ◽  
Kunio HAYASHI ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Bed Rest ◽  
Therapeutic Regimen ◽  
Hemodynamic Effects ◽  
Salt Diet ◽  
Low Salt

scholarly journals Sacubitril/valsartan (LCZ696) Significantly Reduces Aldosterone and Increases cGMP Circulating Levels in a Canine Model of RAAS Activation

2018 ◽  
Author(s):  
Jonathan P Mochel ◽  
Chi Hse Teng ◽  
Mathieu Peyrou ◽  
Jerome Giraudel ◽  
Meindert Danhof ◽  
...  
Keyword(s):  
Heart Failure ◽  
Systemic Exposure ◽  
Plasma Renin ◽  
Canine Model ◽  
Angiotensin Receptors ◽  
Angiotensin I ◽  
Once Daily ◽  
Salt Diet ◽  
Low Salt ◽  
Circulating Levels

AbstractSimultaneous blockade of angiotensin receptors and enhancement of natriuretic peptides (NP) by the first-in-class angiotensin receptor neprilysin (NEP) inhibitor sacubitril/valsartan constitutes an effective approach to treating heart failure. This study examined the effects of sacubitril/valsartan (225 and 675mg/day) vs. placebo, sacubitril (360mg/day), valsartan (900mg/day), and benazepril (5mg/day) on the dynamics of the renin-angiotensin-aldosterone system (RAAS) and the NP system in dogs. Beagle dogs (n=18) were fed a low-salt diet (0.05% Na) for 15 days to model RAAS activation observed in clinical heart failure. Drugs were administered once daily during the last 10 days, while the effects on the RAAS and NPs were assessed on days 1, 5, and 10. Steady-state pharmacokinetics of the test agents were evaluated on day 5. Compared with placebo, sacubitril/valsartan (675mg) substantially increased cGMP circulating levels, while benazepril and valsartan showed no effect. Additionally, sacubitril/valsartan (675mg) and valsartan significantly increased plasma renin activity, angiotensin I and angiotensin II concentrations. Finally, sacubitril/valsartan (both doses), and valsartan significantly decreased plasma aldosterone vs. placebo. Systemic exposure to valsartan following sacubitril/valsartan 675mg administration was similar to that observed with valsartan 900mg administration alone. Sacubitril/valsartan favorably modulates the dynamics of the renin and NP cascades through complementary NEP and RAAS inhibition.

The Low Salt Syndromes in Congestive Heart Failure

1957 ◽  
Vol 41 (1) ◽  
pp. 67-74 ◽  
Author(s):  
George W. Ferenzi ◽  
Peter J. Talso
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Low Salt

Aldosterone augments Na+-induced reduction of cardiac norepinephrine reuptake

2014 ◽  
Vol 307 (8) ◽  
pp. H1169-H1177 ◽  
Author(s):  
Michael M. Kreusser ◽  
Lorenz H. Lehmann ◽  
Johannes H. Riffel ◽  
Markus Haass ◽  
Christiane Maser-Gluth ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Plasma Levels ◽  
Marked Reduction ◽  
Wistar Rats ◽  
Disease Model ◽  
Elevated Plasma ◽  
Langendorff Preparation ◽  
Low Salt ◽  
Net Release

Impairment of the cardiac norepinephrine (NE) reuptake by the neuronal NE transporter contributes to enhanced cardiac NE net release in congestive heart failure. Elevated plasma levels of aldosterone (AL) promote sympathetic overstimulation in failing hearts by unclear mechanisms. Our aim was to evaluate if elevated AL and/or alterations in Na+ intake regulate cardiac NE reuptake. To test the effects of AL and Na+ on cardiac NE reuptake, Wistar rats were fed a normal-salt (NS) diet (0.2% NaCl), a low-salt (LS) diet (0.015% NaCl), or a high-salt (HS) diet (8% NaCl). Another group of animals received AL infusion alone (0.75 μg/h) or AL infusion plus HS diet. Specific cardiac [3H]NE uptake via the NE transporter in a Langendorff preparation and AL plasma levels were measured at different time points between 5 and 42 days of treatment. To compare these findings from healthy animals with a disease model, Dahl salt-sensitive rats were investigated as a model of congestive heart failure with endogenously elevated AL. In summary, neither exogenous nor endogenous elevations of AL alone were sufficient to reduce cardiac NE reuptake. Only the HS diet induced a reduction of NE reuptake by 26%; additional infusion of AL augmented this effect to a further reduction of NE reuptake by 36%. In concordance, Dahl salt-sensitive rats treated with a HS diet displayed elevated AL and a marked reduction of NE reuptake. We conclude that exogenous or endogenous AL elevations alone do not reduce cardiac NE reuptake, but AL serves as an additional factor that negatively regulates cardiac NE reuptake in concert with HS intake.

scholarly journals Intervensi Health Coaching dalam Meningkatkan Self-Care Management Pasien Heart Failure

2021 ◽  
Vol 4 (2) ◽  
pp. 487-496
Author(s):  
Asriyani Hamid ◽  
Elly L Sjattar ◽  
Kusrini S Kadar
Keyword(s):  
Heart Failure ◽  
Care Management ◽  
Total Duration ◽  
Self Care ◽  
Health Coaching ◽  
Training Methods ◽  
Salt Diet ◽  
Cochrane Database ◽  
Low Salt ◽  
Literature Reviews

This study aims to identify the literature that explores health coaching interventions in improving Heart Failure (HF) self-care management, focusing on the total duration and type of health coaching media. The research method uses literature reviews by tracing publications between 2017-2020, the Cochrane database, PubMed, ScienceDirect, ProQuest, and Garuda. The results identified five health coaching studies according to inclusion criteria and resulted in significant improvements in HF self-care management, including symptom reporting, increased physical activity, low-salt diet, fluid and drug intake, self-efficacy, adherence to measuring body weight and blood pressure, and changes. Lifestyle, even though there are differences in the health training methods used. In conclusion, the duration and different media from each study did not significantly influence improving HF self-care management.   Keywords: Heart Failure, Self-Care Management, Health Development

scholarly journals Recommendation of Low-Salt Diet and Short-term Outcomes in Heart Failure with Preserved Systolic Function

2009 ◽  
Vol 122 (11) ◽  
pp. 1029-1036 ◽  
Author(s):  
Scott L. Hummel ◽  
Anthony C. DeFranco ◽  
Stephen Skorcz ◽  
Cecelia K. Montoye ◽  
Todd M. Koelling
Keyword(s):  
Heart Failure ◽  
Systolic Function ◽  
Short Term ◽  
Salt Diet ◽  
Low Salt
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