scholarly journals Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials

BMJ ◽  
2003 ◽  
Vol 326 (7404) ◽  
pp. 1427-0 ◽  
Author(s):  
M R Law
Keyword(s):  
Blood Pressure ◽  
Combination Treatment ◽  
Low Dose ◽  
Randomised Trials ◽  
Blood Pressure Lowering ◽  
Pressure Lowering ◽  
Drugs Analysis ◽  
Dose Combination

Blood pressure lowering action of adenosine diphosphate and related compounds

1961 ◽  
Vol 201 (6) ◽  
pp. 1123-1125 ◽  
Author(s):  
David B. Gordon ◽  
Donald H. Hesse
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Intravenous Injection ◽  
Low Dose ◽  
Adenosine Diphosphate ◽  
Blood Pressure Lowering ◽  
Arterial Blood ◽  
Pressure Lowering ◽  
Dose Levels ◽  
Related Compounds

It was found upon intravenous injection of adenosine and its mono-, di-, and triphosphate in the rat that ADP produced the greatest fall in arterial blood pressure. At low dose levels ADP was about 147 times as potent as adenosine and about 45 times as potent as AMP or ATP on an equimolar basis. The rat is more sensitive to the blood pressure lowering action of the adenosine compounds than other species thus far tested.

Low-dose aspirin does not interfere with the blood pressure-lowering effects of antihypertensive therapy.

2002 ◽  
Vol 20 (5) ◽  
pp. 1015-1022 ◽  
Author(s):  
Alberto Zanchetti ◽  
Lennart Hansson ◽  
Gastone Leonetti ◽  
Karl-Heinz Rahn ◽  
Luis Ruilope ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Antihypertensive Therapy ◽  
Low Dose ◽  
Blood Pressure Lowering ◽  
Dose Aspirin ◽  
Low Dose Aspirin ◽  
Pressure Lowering
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