scholarly journals The role of academic health centres in building equitable health systems: a systematic review protocol

BMJ Open ◽  
2017 ◽  
Vol 7 (5) ◽  
pp. e015435 ◽  
Author(s):  
Alexandra Edelman ◽  
Judy Taylor ◽  
Pavel V Ovseiko ◽  
Stephanie M Topp
BMJ Open ◽  
2016 ◽  
Vol 6 (5) ◽  
pp. e011266 ◽  
Author(s):  
Annesinah Hlengiwe Moloi ◽  
David Watkins ◽  
Mark E Engel ◽  
Sumaya Mall ◽  
Liesl Zühlke

2020 ◽  
Author(s):  
Sohaib R Rufai ◽  
Noor ul Owase Jeelani ◽  
Rebecca J McLean

Abstract Introduction Craniosynostosis is characterised by the premature fusion of cranial sutures. This can be associated with raised intracranial pressure (ICP), which can lead to developmental delay, visual impairment and death. Treatment involves surgical expansion of the skull vault. There is no consensus over who to treat and when. Intracranial pressure is difficult to estimate in a child and existing methods possess sub-optimal diagnostic accuracy to be employed as screening tools. Here, we propose a systematic review protocol to examine the role of optical coherence tomography (OCT) in early detection of raised ICP in craniosynostosis. Methods Electronic searches in the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and Embase will identify studies featuring OCT in detecting raised ICP in children with craniosynostosis. Two independent researchers will identify studies for inclusion using a screening questionnaire. Quality will be assessed using the National Institutes of Health (NIH) Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. The primary outcome measure is the sensitivity and specificity of OCT in detecting raised ICP in children with craniosynostosis. Secondary outcomes measures include the sensitivity and specificity of other surrogate measures for raised ICP, OCT parameters used and normal ranges for ICP reported. A formal narrative synthesis with descriptive statistics will be presented. Discussion The proposed study will be the first to examine the role of optical coherence tomography in the early recognition of raised intracranial pressure in craniosynostosis, thereby addressing an important clinical problem in paediatric ophthalmology and craniofacial surgery. This systematic review protocol provides transparency to the proposed methods and reduces the possibility of duplication. The proposed methods reflect those prescribed by the Cochrane Collaboration. Systematic review registration International Prospective Register for Systematic Reviews (PROSPERO) number CRD42019147693


2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Jill Fortuin ◽  
Faatiema Salie ◽  
Leila H. Abdullahi ◽  
Tania S. Douglas

Medwave ◽  
2021 ◽  
Vol 21 (06) ◽  
pp. e8223-e8223
Author(s):  
Stefanie Arce Pardo ◽  
Shuheng Lai ◽  
Luis Ortiz-Muñoz ◽  
Francisca Verdugo-Paiva ◽  
Gabriel Rada

Objective This living systematic review aims to provide a timely, rigorous and continuously updated summary of the evidence available on the role of pulmonary rehabilitation in the treatment of patients with COVID-19. Design This is the protocol of a living systematic review. Data sources We will conduct searches in the L·OVE (Living OVerview of Evidence) platform for COVID-19, a system that maps PICO questions to a repository maintained through regular searches in electronic databases, preprint servers, trial registries and other resources relevant to COVID-19. No date or language restrictions will be applied. Eligibility criteria for selecting studies and methods We adapted an already published common protocol for multiple parallel systematic reviews to the specificities of this question. We will include randomized trials evaluating the effect of pulmonary rehabilitation as monotherapy or in combination with other interventions-versus sham or no treatment in patients with COVID-19. Two reviewers will independently screen each study for eligibility, extract data, and assess the risk of bias. We will pool the results using meta-analysis and will apply the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system to assess the certainty of the evidence for each outcome. Ethics and dissemination No ethics approval is considered necessary. The results of this review will be widely disseminated via peer-reviewed publications, social networks and traditional media.


2020 ◽  
Author(s):  
Luis E. Ortiz-Muñoz ◽  
Francisca Verdugo-Paiva ◽  
Rocío Bravo-Jeria ◽  
Macarena Morel ◽  
María Paz Acuña ◽  
...  

Objetive : This living systematic review aims to provide a timely, rigorous and continuously updated summary of the evidence available on the role of ivermectin in the treatment of patients with COVID-19


2020 ◽  
Author(s):  
Francisca Verdugo ◽  
María Paz Acuña ◽  
Ivan Solà ◽  
Gabriel Rada

This living systematic review aims to provide a timely, rigorous and continuously updated summary of the evidence available on the role of remdesivir in the treatment of patients with COVID-19. PROSPERO RegistrationCRD42020183384


BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e036177
Author(s):  
Fabio Alexis Rincón Uribe ◽  
Cristian Ariel Neira Espejo ◽  
Janari da Silva Pedroso

IntroductionAdolescence is a critical period of human development, where adaptive or maladaptive experiences can happen. These experiences are associated with psychological, social, biological and health factors. Previous empirical evidence suggests that mental health is associated with individual assets and positive states, whose presence may become a factor of protection and resistance to mental disorders. Among these, optimism could play a fundamental role in sustaining physical and mental well-being and in dealing with threats potentially harmful to health. Given the rise of research on optimism and its importance in the various health outcomes, it is necessary to initiate processes of compilation and synthesis of this evidence to facilitate the understanding of the importance of this variable on the mental health of adolescents.Methods and analysisThe included studies will be experimental, observational, cross-sectional and longitudinal focussed on the role of optimism on mental health in adolescents, regardless of whether they belong to clinical or non-clinical populations. This systematic review protocol will be carried out following the Cochrane Manual for systematic reviews and will follow the statement on systematic reviews and meta-analysis of PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols). Searches will run from October 2019 to March 2020, and will be carried out from the following electronic databases: APA PsycNet, BVS (Biblioteca Virtual em Saúde), Web of Science, PubMed Central and Scopus. Two reviewers will obtain the eligible articles, published from January 2009 onward, to assess the quality of each study and extract the data. For the presentation of the results, a narrative and quantitative synthesis will be carried out that groups the data found.Ethics and disseminationThe approval of an ethics committee is not required for a systematic review protocol. The results will be presented at congresses in social sciences and psychology and will be published in a peer-reviewed social or health science journal.PROSPERO registration numberPROSPERO CRD42019142616.


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