Rowachol for gallstone dissolution?

Drug and Therapeutics Bulletin ◽

10.1136/dtb.23.19.75 ◽

1985 ◽

Vol 23 (19) ◽

pp. 75-76

Keyword(s):

Combination Therapy ◽

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Common Duct ◽

Cholesterol Gallstones ◽

Gallstone Dissolution ◽

Rowachol (Tillotts) is a mixture of monoterpenes intended for the dissolution of cholesterol gallstones, as an adjunct to the existing drugs chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA) whose use we discussed last month.1 When combined with CDCA, Rowachol is claimed to dissolve stones in the common duct. This article assesses its efficacy both alone and in combination therapy.

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Medical treatment of gallstones: ursodeoxycholic acid

Drug and Therapeutics Bulletin ◽

10.1136/dtb.22.4.13 ◽

1984 ◽

Vol 22 (4) ◽

pp. 13-15

Keyword(s):

Medical Treatment ◽

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Cholesterol Gallstones ◽

Dissolution Of Gallstones

We discussed the dissolution of gallstones with chenodeoxycholic acid (CDCA) (Chendol - CP Pharmaceuticals; Chenofalk - Thames) five years ago.1 Now a second drug, ursodeoxycholic acid (UDCA) (Destolit - Merrell; Ursofalk - Thames) is available for the same purpose. Like CDCA it is given by mouth to dissolve non-calcified cholesterol gallstones in the gallbladder. Several potential advantages are claimed for UDCA; what is its place in treatment?

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Lichen planus associated with chenodeoxycholic acid and ursodeoxycholic acid for gallstone dissolution

Digestive Diseases and Sciences ◽

10.1007/bf01307592 ◽

1992 ◽

Vol 37 (4) ◽

pp. 628-630 ◽

Author(s):

Joseph P. M. Ellul ◽

Richard Groves ◽

Julian R. F. Walters ◽

Gerard M. Murphy

Keyword(s):

Ursodeoxycholic Acid ◽

Lichen Planus ◽

Chenodeoxycholic Acid ◽

Gallstone Dissolution

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Combination Therapy of Chenodeoxycholic Acid and Ursodeoxycholic Acid

Gallstone Disease ◽

10.1007/978-3-642-74619-2_15 ◽

1990 ◽

pp. 127-133

Author(s):

M. Podda ◽

M. Zuin ◽

M. L. Petroni ◽

E. Bertolini ◽

A. Crosignani ◽

...

Keyword(s):

Combination Therapy ◽

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid

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Principles of Gallstone Dissolution with Chenodeoxycholic Acid, Ursodeoxycholic Acid, and the Combination of both Bile Acids

Gallstone Disease ◽

10.1007/978-3-642-74619-2_13 ◽

1990 ◽

pp. 115-120

Author(s):

A. Stiehl

Keyword(s):

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Gallstone Dissolution

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Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: a randomized multicentre trial

Alimentary Pharmacology & Therapeutics ◽

10.1046/j.1365-2036.2001.00853.x ◽

2001 ◽

Vol 15 (1) ◽

pp. 123-128 ◽

Author(s):

◽

M. L. Petroni ◽

R. P. Jazrawi ◽

P. Pazzi ◽

A. Lanzini ◽

...

Keyword(s):

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Multicentre Trial ◽

Cholesterol Gallstones

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A Combination Therapy With Simvastatin and Ursodeoxycholic Acid Is More Effective for Cholesterol Gallstone Dissolution Than Is Ursodeoxycholic Acid Monotherapy

Journal of Clinical Gastroenterology ◽

10.1097/00004836-199806000-00015 ◽

1998 ◽

Vol 26 (4) ◽

pp. 287-291 ◽

Author(s):

Susumu Tazuma ◽

Goro Kajiyama ◽

Toshiyuki Mizuno ◽

Gunji Yamashita ◽

Hiroyuki Miura ◽

...

Keyword(s):

Combination Therapy ◽

Ursodeoxycholic Acid ◽

Cholesterol Gallstone ◽

Gallstone Dissolution

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A clinical studies on gallstone patients rate in multiphasic healthy testing system and gallstone dissolution therapy. Comparison of efficacy between the single administration of ursodeoxycholic acid (UDC) and the combined therapy of UDC and chenodeoxycholic acid (CDC).

Japanese journal of MHTS ◽

10.7143/jhep1985.13.280 ◽

1986 ◽

Vol 13 (3) ◽

pp. 280-284

Author(s):

TATSUYA KOJIMA

Keyword(s):

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Clinical Studies ◽

Combined Therapy ◽

Testing System ◽

Single Administration ◽

Gallstone Dissolution

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Comparison on Response and Dissolution Rates Between Ursodeoxycholic Acid Alone or in Combination With Chenodeoxycholic Acid for Gallstone Dissolution According to Stone Density on CT Scan

Medicine ◽

10.1097/md.0000000000002037 ◽

2015 ◽

Vol 94 (50) ◽

pp. e2037 ◽

Author(s):

Jae Min Lee ◽

Jong Jin Hyun ◽

In Young Choi ◽

Suk Keu Yeom ◽

Seung Young Kim ◽

...

Keyword(s):

Ct Scan ◽

Ursodeoxycholic Acid ◽

Chenodeoxycholic Acid ◽

Dissolution Rates ◽

Gallstone Dissolution ◽

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Pharmacological studies on the hepato-biliary system (Rept.20): Biliary bile acid composition changes during gallstone dissolution by chenodeoxycholic acid and ursodeoxycholic acid in hamsters.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)64857-2 ◽

1983 ◽

Vol 33 ◽

pp. 164

Author(s):

Saizo Yanaura ◽

Yoshiko Ida ◽

Akira Iizuka ◽

Miwa Misawa

Keyword(s):

Bile Acid ◽

Ursodeoxycholic Acid ◽

Acid Composition ◽

Chenodeoxycholic Acid ◽

Biliary System ◽

Gallstone Dissolution ◽

Biliary Bile Acid ◽

Pharmacological Studies ◽

Composition Changes

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Effects on serum lipoproteins of high-dose chenodeoxycholic acid (CDCA) in patients with cholesterol gallstones and of preventive low-dose after gallstone dissolution

Journal of Hepatology ◽

10.1016/s0168-8278(85)80288-9 ◽

1985 ◽

Vol 1 ◽

pp. S108

Keyword(s):

Chenodeoxycholic Acid ◽

Low Dose ◽

High Dose ◽

Serum Lipoproteins ◽

Cholesterol Gallstones ◽

Gallstone Dissolution

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