scholarly journals Contribution of creatine kinase MB mass concentration at admission to early diagnosis of acute myocardial infarction.

Heart ◽  
1994 ◽  
Vol 72 (2) ◽  
pp. 112-118 ◽  
Author(s):  
A J Bakker ◽  
J P Gorgels ◽  
B van Vlies ◽  
M J Koelemay ◽  
R Smits ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Early Diagnosis ◽  
Mass Concentration ◽  
Creatine Kinase Mb

scholarly journals Comparison of serum myoglobin and creatine kinase MB isoenzyme in early diagnosis of acute myocardial infarction.

Heart ◽  
1981 ◽  
Vol 45 (4) ◽  
pp. 389-392 ◽  
Author(s):  
A P Freeman ◽  
K R Fatches ◽  
I W Carter ◽  
M J Cloonan ◽  
D E Wilcken
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Early Diagnosis ◽  
Creatine Kinase Mb ◽  
Serum Myoglobin

Early detection of acute myocardial infarction by measurement of mass concentration of creatine kinase-MB

1991 ◽  
Vol 68 (17) ◽  
pp. 1545-1550 ◽  
Author(s):  
Johannes Mair ◽  
Erika Artner-Dworzak ◽  
Anton Dienstl ◽  
Peter Lechleitner ◽  
Bernhard Morass ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Early Detection ◽  
Mass Concentration ◽  
Creatine Kinase Mb

Analytical and Clinical Evaluation of Creatine Kinase MB Mass Assay by IMx: Comparison with MB Isoenzyme Activity and Serum Myoglobin for Early Diagnosis of Myocardial Infarction

1992 ◽  
Vol 38 (12) ◽  
pp. 2380-2386 ◽  
Author(s):  
M Van Blerk ◽  
V Maes ◽  
L Huyghens ◽  
M P Derde ◽  
R Meert ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Early Diagnosis ◽  
Predictive Value ◽  
Diagnostic Performance ◽  
Creatine Kinase Mb ◽  
Sensitivity Specificity ◽  
Serum Myoglobin

Abstract We analytically and clinically evaluated Abbott's IMx assay for creatine kinase (CK) isoenzyme MB (CK-MB) in serum. Over a 1-year period, the method was more specific but less precise than catalytic isoenzyme measurements by electrophoresis or immunoinhibition. Sera from different individuals without electrophoretic evidence of CK-MB but containing macro CK type 1 (n = 20), mitochondrial CK (n = 5), or CK-BB (n = 5) were scored as CK-MB negative by the IMx. Likewise, CK-MB-negative by the sera remained so after addition of purified human CK-MM (< or = 7600 U/L) or CK-BB (< or = 8100 U/L). For 39 patients admitted for suspicion of uncomplicated acute myocardial infarction (precordial pain for < or = 4 h), the diagnostic performance of the IMx CK-MB assay on admission and 4 h later was superior to that of total CK activity and compared well with that of CK-MB activity measured by electrophoresis or immunoinhibition. An admission, myoglobin showed a higher diagnostic sensitivity, specificity, and predictive value than did CK-MB and was the most informative test. Diagnostic performance on admission and 4 h later was further improved by considering positivity for myoglobin and for CK-MB by IMx and for the change in each over the first 4 h of hospitalization as criteria. Twelve hours after admission, diagnostic performance was further improved for all CK and CK-MB methods but began to decline for myoglobin.

Improved Specificity of Myoglobin Plus Carbonic Anhydrase Assay Versus That of Creatine Kinase-MB for Early Diagnosis of Acute Myocardial Infarction

1996 ◽  
Vol 27 (1) ◽  
pp. 22-28 ◽  
Author(s):  
Gerard X Brogan ◽  
Juhani Vuori ◽  
Solomon Friedman ◽  
Charles F McCuskey ◽  
Henry C Thode ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Carbonic Anhydrase ◽  
Early Diagnosis ◽  
Creatine Kinase Mb

scholarly journals Early diagnosis of acute myocardial infarction based on assay for subforms of creatine kinase-MB.

Circulation ◽  
1990 ◽  
Vol 82 (3) ◽  
pp. 759-764 ◽  
Author(s):  
P R Puleo ◽  
P A Guadagno ◽  
R Roberts ◽  
M V Scheel ◽  
A J Marian ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Early Diagnosis ◽  
Creatine Kinase Mb

Differences in the time course of creatine kinase-MB activity and mass concentration after acute myocardial infarction

1993 ◽  
Vol 219 (1-2) ◽  
pp. 183-188 ◽  
Author(s):  
Hannsjörg H.E. Baum ◽  
Ingrid Schwab ◽  
Peter Boekstegers ◽  
Gerd Steinbeck ◽  
Dieter Neumeier
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Creatine Kinase ◽  
Mass Concentration ◽  
Time Course ◽  
Creatine Kinase Mb
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