Synchronous primary endometrial and ovarian cancer with three different histologic patterns: A case report

2003 ◽  
Vol 13 (5) ◽  
pp. 678-682 ◽  
Author(s):  
Y.-S. Ree ◽  
S.-H. Cho ◽  
S.-R. Kim ◽  
S.-H. Cho ◽  
K.-T. Kim ◽  
...  
Keyword(s):  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Figo Stage ◽  
Primary Cancer ◽  
Metastatic Lesions ◽  
Synchronous Cancers ◽  
Stage Ia ◽  
The Right ◽  
Female Genital

Synchronous cancers involving both endometrium and ovary in the female genital tract is a well-recognized phenomenon. However, most of them are metastatic lesions arising from one organ and simultaneous primary cancer occurring in both organs is relatively rare. We report a case with dual primary cancer occurring in both ovaries and endometrium with three different histologies. Recently, a 46-year-old women presented with vaginal bleeding was found to have FIGO stage IC clear cell carcinoma of the left ovary, stage IA borderline mucinous cystadoma of the right ovary, and stage IB endometrial carcinoma of endometrioid type. We present this case with a brief review of references.

Cytologic Features of Clear Cell Carcinoma of the Female Genital Tract

2004 ◽  
Vol 48 (1) ◽  
pp. 47-51 ◽  
Author(s):  
José A. Jiménez-Heffernan ◽  
Blanca Vicandi ◽  
Pilar González-Peramato ◽  
Ana Pérez-Campos ◽  
Pilar López-Ferrer ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Genital Tract ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Female Genital

Cytology of Clear Cell Carcinoma of the Female Genital Tract in Fine Needle Aspirates and Ascites

2000 ◽  
Vol 44 (6) ◽  
pp. 1005-1009 ◽  
Author(s):  
Şafak Atahan ◽  
Cemil Ekinci ◽  
Fikri İçli ◽  
Nural Erdoğan
Keyword(s):  
Cell Carcinoma ◽  
Genital Tract ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Female Genital

Clear Cell Adenocarcinoma of the Female Genital Tract: Long-Term Outcome and Fertility Aspects After Brachytherapy Aimed at a Conservative Treatment

2012 ◽  
Vol 22 (8) ◽  
pp. 1378-1382 ◽  
Author(s):  
Nicolas Magné ◽  
Cyrus Chargari ◽  
Antonin Levy ◽  
Carlos Rodriguez ◽  
Véronique De Vos ◽  
...  
Keyword(s):  
Conservative Treatment ◽  
Pregnancy Rate ◽  
Genital Tract ◽  
Clear Cell ◽  
Female Genital Tract ◽  
Disease Free Survival ◽  
Good Survival ◽  
Clear Cell Adenocarcinoma ◽  
Long Term Outcome ◽  
Female Genital

ObjectivesTo assess the outcome and the fertility aspects in the particular population of cervical and/or vaginal clear cell adenocarcinoma (CCA) associated or not to previous in utero diethylstilbestrol exposure.MethodsFrom January 1970 to December 2003, data from 61 consecutive patients with cervical and/or vaginal histologically proven CCA treated with brachytherapy (BT) aimed at a conservative treatment at the Institut Gustave Roussy as a part of treatment were retrospectively analyzed.ResultsThe median follow-up was 9.4 years, ranging from 0.3 to 27.4 years. The 5-year specific overall survival rate was 79%. The median time of disease-free survival was 5.8 years. In the subgroup of 42 patients with a cervical CCA, 12 patients tried to be pregnant, 2 patients became pregnant and had miscarriages (P2M2 and P1M1). No pregnancy has been observed in 10 patients exclusively owing to anomalies of the reproductive tract: 6 patients had partial or total diaphragm, 2 patients had an anatomical alteration of the uterus, 1 patient had atrophic endometrium, and 1 patient had primary infertility. In the subgroup of 19 patients with a vaginal CCA, 7 patients tried to be pregnant. All of them had no morphological and/or functional anomalies of the genital tract. Three of 7 patients had delivered healthy babies (P1D1, P2D2, and P3M2D1), and another one had a miscarriage (P1M1). Moreover, all babies were delivered by cesarean section. The pregnancy rate was 10% (6 of 61 patients) with 3 healthy babies.ConclusionConservative approach in patients with female genital tract CCA including BT gives good results with good survival rates and an interesting global pregnancy rate.

scholarly journals A Rare Case of Clear Cell Carcinoma, Müllerian Type in the Renal Pelvis of a 21-Year-Old Woman

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Diandra Perez ◽  
Rana Naous
Keyword(s):  
Cell Carcinoma ◽  
Renal Pelvis ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Female Genital Tract ◽  
Neoplastic Cells ◽  
Primary Location ◽  
Foamy Macrophages ◽  
Vacuolated Cytoplasm

Clear Cell Carcinomas of Müllerian origin are extremely rare within the upper urinary system. Their morphology is identical to that of the Clear Cell Carcinomas of the female genital tract. When they arise in the urinary tract, it is thought to be due to ectopic Müllerian embryogenesis. Here, we present a case of a 21-year-old woman with a Clear Cell Carcinoma, Müllerian type, arising from the renal pelvis. Histologically, it consisted of tubulopapillary architecture with associated foamy macrophages and a mucinous background. The neoplastic cells exhibited variably sized round nuclei with prominent nucleoli, eosinophilic to vacuolated cytoplasm with occasional intracytoplasmic mucin vacuoles, and a hobnail appearance. Immunohistochemical stains showed that the neoplastic cells were positive for Pax-8, p53, CK7, HMWK 903, and INI-1 and focally positive for p504s (AMACR). The neoplastic cells were negative for GATA-3, CK5/CK6, p63, CK20, and CDX-2 immunostains, ruling out urothelial or enteric phenotype. Additional immunostains performed by an outside institution showed that the neoplastic cells were positive for HNF-1β. The overall morphology and immunophenotype were consistent with Clear Cell Carcinoma of Müllerian origin arising from the renal pelvis. Follow-up revealed no metastasis or other tumor sites, supporting that this was the primary location.

FIGO stage IB clear cell carcinoma and adenocarcinoma of uterine cervix

2005 ◽  
Vol 16 (4) ◽  
pp. 307
Author(s):  
Jin Hee Kim ◽  
Eun Sun Choi ◽  
Dae Yeon Kim ◽  
Dae Sik Suh ◽  
Jong Hyeok Kim ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Uterine Cervix ◽  
Clear Cell ◽  
Clear Cell Carcinoma ◽  
Figo Stage ◽  
Stage Ib

scholarly journals Rotura Uterina às 18 Semanas de Gravidez no Contexto de Útero Malformado

2016 ◽  
Vol 29 (10) ◽  
pp. 667
Author(s):  
Emídio Vale-Fernandes ◽  
Neusa Teixeira ◽  
Alexandra Cadilhe ◽  
Maria José Rocha
Keyword(s):  
Uterine Rupture ◽  
Female Genital Tract ◽  
Obstetric Outcomes ◽  
Placenta Increta ◽  
Abnormal Placentation ◽  
History Of ◽  
Uterine Malformations ◽  
The Right ◽  
Congenital Uterine Anomaly ◽  
Female Genital

Birth defects of the female genital tract are relatively common and often asymptomatic. Despite the pregnancy outcome can be favorable, adverse obstetric outcomes are described in women with uterine malformations. The authors report the case of an obstetric emergency which enhances the possibility of a very adverse and rare outcome of uterine rupture in a left hemi-cavity of a bicornuate uterus away from the term, at 18 weeks of pregnancy, in a pregnant woman with history of caesarean in the right hemi-cavity and with placenta increta. A malformed uterus with a primitive type cavity has lower distensibility of the wall with the progression of the pregnancy and facilitates the development of abnormal placentation forms, increasing the risk of uterine rupture in the first and second trimesters. The knowledge of the existence of a congenital uterine anomaly in the preconceptional period is of primary importance.

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