OP69 Regression discontinuity designs in the evaluation of health interventions, policies, and outcomes: a systematic review

2016 ◽  
Vol 70 (Suppl 1) ◽  
pp. A39.2-A39 ◽  
Author(s):  
ML Hilton Boon ◽  
P Craig ◽  
L Moore ◽  
H Thomson
Author(s):  
Mandeep Sekhon ◽  
Claire White ◽  
Emma Godfrey ◽  
Aliya Amirova ◽  
Åsa Revenäs ◽  
...  

Abstract Objective The aim of this systematic review was to assess the evidence from randomised controlled trials (RCT) and cohort studies for the effectiveness of digital interventions designed to enhance adherence to physical activity (PA) for people with inflammatory arthritis (IA) and describe the intervention content using established coding criteria. Methods Six electronic databases were searched for published and unpublished studies. Independent data extraction and quality assessment (Cochrane risk of bias II or ROBIN I) were conducted by two reviewers. The primary outcome was self-reported adherence to PA post-intervention. Secondary outcomes included self-reported adherence to PA at other timepoints, level of PA or engagement with intervention at any follow-up timepoint. Intervention content was assessed using the Consensus on Exercise Reporting Template and the Behaviour Change Techniques taxonomy version 1. Results From 11,136 reports, four moderate risk of bias studies (three RCTs, one cohort study) including 1,160 participants with rheumatoid arthritis or juvenile inflammatory arthritis were identified. Due to heterogeneity of outcomes, a narrative synthesis was conducted. Only one RCT reported a small between group difference in adherence to PA [mean difference (95% confidence intervals) -0.46 (-0.82. -0.09)] in favour of the intervention. There were no between group differences in any secondary outcomes. Interventions included between 3–11 behaviour change techniques but provided minimal exercise prescription information. Conclusion There is currently limited moderate quality evidence available to confidently evaluate the effect of web-based and mobile health interventions on adherence to PA or level of PA post intervention in people with IA.


2020 ◽  
pp. 1-17
Author(s):  
Erin Hartman

Abstract Regression discontinuity (RD) designs are increasingly common in political science. They have many advantages, including a known and observable treatment assignment mechanism. The literature has emphasized the need for “falsification tests” and ways to assess the validity of the design. When implementing RD designs, researchers typically rely on two falsification tests, based on empirically testable implications of the identifying assumptions, to argue the design is credible. These tests, one for continuity in the regression function for a pretreatment covariate, and one for continuity in the density of the forcing variable, use a null of no difference in the parameter of interest at the discontinuity. Common practice can, incorrectly, conflate a failure to reject evidence of a flawed design with evidence that the design is credible. The well-known equivalence testing approach addresses these problems, but how to implement equivalence tests in the RD framework is not straightforward. This paper develops two equivalence tests tailored for RD designs that allow researchers to provide statistical evidence that the design is credible. Simulation studies show the superior performance of equivalence-based tests over tests-of-difference, as used in current practice. The tests are applied to the close elections RD data presented in Eggers et al. (2015b).


2017 ◽  
Vol 3 (2) ◽  
pp. 134-146
Author(s):  
Matias D. Cattaneo ◽  
Gonzalo Vazquez-Bare

Author(s):  
Anil Babu Payedimarri ◽  
Diego Concina ◽  
Luigi Portinale ◽  
Massimo Canonico ◽  
Deborah Seys ◽  
...  

Artificial Intelligence (AI) and Machine Learning (ML) have expanded their utilization in different fields of medicine. During the SARS-CoV-2 outbreak, AI and ML were also applied for the evaluation and/or implementation of public health interventions aimed to flatten the epidemiological curve. This systematic review aims to evaluate the effectiveness of the use of AI and ML when applied to public health interventions to contain the spread of SARS-CoV-2. Our findings showed that quarantine should be the best strategy for containing COVID-19. Nationwide lockdown also showed positive impact, whereas social distancing should be considered to be effective only in combination with other interventions including the closure of schools and commercial activities and the limitation of public transportation. Our findings also showed that all the interventions should be initiated early in the pandemic and continued for a sustained period. Despite the study limitation, we concluded that AI and ML could be of help for policy makers to define the strategies for containing the COVID-19 pandemic.


2020 ◽  
Vol 8 (1) ◽  
pp. 164-181
Author(s):  
Cristian Crespo

Abstract This paper elaborates on administrative sorting, a threat to internal validity that has been overlooked in the regression discontinuity (RD) literature. Variation in treatment assignment near the threshold may still not be as good as random even when individuals are unable to precisely manipulate the running variable. This can be the case when administrative procedures, beyond individuals’ control and knowledge, affect their position near the threshold non-randomly. If administrative sorting is not recognized it can be mistaken as manipulation, preventing fixing the running variable and leading to discarding viable RD research designs.


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