PATH60 Demonstration of the time course of retrograde trans-synaptic degeneration in the visual system using optical coherence tomography

2010 ◽  
Vol 81 (11) ◽  
pp. e23-e24
Author(s):  
P. Jindahra ◽  
G. T. Plant ◽  
A. Petrie
Keyword(s):  
Optical Coherence Tomography ◽  
Visual System ◽  
Time Course ◽  
Optical Coherence ◽  
Synaptic Degeneration

scholarly journals Correlation Between Retrograde Trans-Synaptic Degeneration of Ganglion Cells and Optical Coherence Tomography Angiography Following Ischemic Stroke

Cureus ◽  
2021 ◽  
Author(s):  
Mercedes Molero-Senosiain ◽  
Beatriz Vidal-Villegas ◽  
Javier Pascual-Prieto ◽  
Clara Valor-Suarez ◽  
Federico Saenz-Frances ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ischemic Stroke ◽  
Optical Coherence Tomography Angiography ◽  
Ganglion Cells ◽  
Optical Coherence ◽  
Synaptic Degeneration

scholarly journals In vivo Morphometry of Inner Plexiform Layer (IPL) Stratification in the Human Retina With Visible Light Optical Coherence Tomography

2021 ◽  
Vol 15 ◽  
Author(s):  
Tingwei Zhang ◽  
Aaron M. Kho ◽  
Vivek J. Srinivasan
Keyword(s):  
Optical Coherence Tomography ◽  
Visual System ◽  
Visible Light ◽  
Human Subjects ◽  
Plexiform Layer ◽  
Bipolar Cells ◽  
Inner Plexiform Layer ◽  
Optical Coherence ◽  
On And Off Pathways

From the bipolar cells to higher brain visual centers, signals in the vertebrate visual system are transmitted along parallel on and off pathways. These two pathways are spatially segregated along the depth axis of the retina. Yet, to our knowledge, there is no way to directly assess this anatomical stratification in vivo. Here, employing ultrahigh resolution visible light Optical Coherence Tomography (OCT) imaging in humans, we report a stereotyped reflectivity pattern of the inner plexiform layer (IPL) that parallels IPL stratification. We characterize the topography of this reflectivity pattern non-invasively in a cohort of normal, young adult human subjects. This proposed correlate of IPL stratification is accessible through non-invasive ocular imaging in living humans. Topographic variations should be carefully considered when designing studies in development or diseases of the visual system.

scholarly journals Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

10.3791/58571 ◽  
2019 ◽  
Author(s):  
Michael Dietrich ◽  
Christina Hecker ◽  
Alexander Hilla ◽  
Andrés Cruz-Herranz ◽  
Hans-Peter Hartung ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual System ◽  
Optical Coherence ◽  
Optokinetic Response
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