scholarly journals Serum enzyme studies in muscle disease: Part III Serum creatine kinase activity in relatives of patients with the Duchenne type of muscular dystrophy

1964 ◽  
Vol 27 (3) ◽  
pp. 181-185 ◽  
Author(s):  
J. M. S. Pearce ◽  
R. J. T. Pennington ◽  
J. N. Walton
Keyword(s):  
Creatine Kinase ◽  
Muscular Dystrophy ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Muscle Disease ◽  
Serum Enzyme

SERUM CREATINE KINASE ACTIVITY AND CARRIER STATUS FOR DUCHENNE MUSCULAR DYSTROPHY

The Lancet ◽  
1979 ◽  
Vol 314 (8156-8157) ◽  
pp. 1370 ◽  
Author(s):  
D.G. Bullock ◽  
F.M. Mcsweeney ◽  
T.P. Whitehead ◽  
J.H. Edwards
Keyword(s):  
Creatine Kinase ◽  
Duchenne Muscular Dystrophy ◽  
Muscular Dystrophy ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Carrier Status

The contribution of assays for lymphocyte capping and creatine kinase to detection of the Becker-type dystrophy trait.

1980 ◽  
Vol 26 (6) ◽  
pp. 754-759
Author(s):  
B M Goldsmith ◽  
H D Gruemer ◽  
R J Hawley ◽  
N A Pickard ◽  
H L Verrill ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Differential Diagnosis ◽  
Muscular Dystrophy ◽  
Kinase Activity ◽  
Reference Intervals ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Healthy Controls ◽  
Tests And Measurements ◽  
Normal Controls

Abstract Members of three unrelated families with the mild Becker type of muscular dystrophy were subjected to lymphocyte capping tests and measurements of serum creatine kinase activity. Both tests correctly identified all nine affected males, but only the capping test was abnormal in seven of eight obligate carriers. The number of capped cells in carriers and affected persons with the Becker-type dystrophy was generally intermediate between those observed for individuals with the Duchenne trait and normal controls, thus potentially aiding in the differential diagnosis between the two myopathies. The lack of sensitivity of measurements of serum creatine kinase activity in identifying carriers is further complicated by the difficulty of establishing reliable reference intervals for this enzyme in 204 healthy controls. Detailed directions for the performance of the capping test are presented.

The contribution of assays for lymphocyte capping and creatine kinase to detection of the Becker-type dystrophy trait.

1980 ◽  
Vol 26 (6) ◽  
pp. 754-759 ◽  
Author(s):  
B M Goldsmith ◽  
H D Gruemer ◽  
R J Hawley ◽  
N A Pickard ◽  
H L Verrill ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Differential Diagnosis ◽  
Muscular Dystrophy ◽  
Kinase Activity ◽  
Reference Intervals ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Healthy Controls ◽  
Tests And Measurements ◽  
Normal Controls

Abstract Members of three unrelated families with the mild Becker type of muscular dystrophy were subjected to lymphocyte capping tests and measurements of serum creatine kinase activity. Both tests correctly identified all nine affected males, but only the capping test was abnormal in seven of eight obligate carriers. The number of capped cells in carriers and affected persons with the Becker-type dystrophy was generally intermediate between those observed for individuals with the Duchenne trait and normal controls, thus potentially aiding in the differential diagnosis between the two myopathies. The lack of sensitivity of measurements of serum creatine kinase activity in identifying carriers is further complicated by the difficulty of establishing reliable reference intervals for this enzyme in 204 healthy controls. Detailed directions for the performance of the capping test are presented.

Distribution of serum creatine kinase activity in young healthy persons

1999 ◽  
Vol 279 (1-2) ◽  
pp. 107-115 ◽  
Author(s):  
Eli I. Lev ◽  
Ilan Tur-Kaspa ◽  
Isaac Ashkenazy ◽  
Anat Reiner ◽  
David Faraggi ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Kinase Activity ◽  
Creatine Kinase Activity ◽  
Serum Creatine Kinase ◽  
Healthy Persons
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