O-019 Percutaneous Sclerotherapy with Ethanolamine Oleate for Venous Malformations of the Head and Neck

Purpose This manuscript describes the technique of real-time MRI-guided sclerotherapy for low-flow venous malformations in the head and neck based on our institutional experience. Materials and methods Ethanolamine oleate is used as the sclerosant and is mixed with gadolinium for visualization during the procedure. The five procedural steps include: (I) an initial tri-plane T2-weighted sequence to visualize the lesion; (II) a T1 FSE or trueFISP sequence to assess needle placement and advancement within the lesion; (III) a tri-plane T1 FLASH sequence to monitor sclerosant injection; (IV) a T1 FSE or VIBE sequence to assess sclerosant coverage of the malformation before needle removal; (V) a post-procedural tri-plane T1 fat-saturated sequence to confirm sclerosant coverage of the lesion. Periprocedural medications typically include steroids, antibiotic prophylaxis, and non-steroidal anti-inflammatory medication. Patients are typically admitted for overnight observation. Conclusion Real-time MRI-guided sclerotherapy for low-flow venous malformations in the head and neck is effective and safe.

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Effectiveness and safety of foam sclerotherapy with 5% ethanolamine oleate in the treatment of low-flow venous malformations in the head and neck region: a case series

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2017.12.004 ◽

2018 ◽

Vol 47 (7) ◽

pp. 900-907 ◽

Cited By ~ 8

Author(s):

M.C. Ribeiro ◽

S. de Mattos Camargo Grossmann ◽

M.B.F. do Amaral ◽

W.H. de Castro ◽

T.P. Navarro ◽

...

Keyword(s):

Head And Neck ◽

Case Series ◽

Neck Region ◽

Low Flow ◽

Venous Malformations ◽

Ethanolamine Oleate ◽

Foam Sclerotherapy ◽

Head And Neck Region

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P-011 Percutaneous Sclerotherapy with Ethanolamine Oleate for Lymphatic Malformations of the Head and Neck

Journal of NeuroInterventional Surgery ◽

10.1136/neurintsurg-2013-010870.43 ◽

2013 ◽

Vol 5 (Suppl 2) ◽

pp. A24.2-A25

Author(s):

M Alexander ◽

R McTaggart ◽

O Choudhri ◽

M Marcellus ◽

H Do

Keyword(s):

Head And Neck ◽

Ethanolamine Oleate ◽

Lymphatic Malformations ◽

Percutaneous Sclerotherapy

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Sclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis

Neurointervention ◽

10.5469/neuroint.2019.00213 ◽

2020 ◽

Vol 15 (1) ◽

pp. 4-17 ◽

Cited By ~ 3

Author(s):

Lucio De Maria ◽

Paolo De Sanctis ◽

Karthik Balakrishnan ◽

Megha Tollefson ◽

Waleed Brinjikji

Keyword(s):

Systematic Review ◽

Head And Neck ◽

Meta Analysis ◽

Venous Malformations ◽

Cure Rate ◽

Complete Cure ◽

Percutaneous Sclerotherapy ◽

Effective Treatment Modality ◽

The Face ◽

Life Improvement

We performed a systematic review and meta-analysis of studies performing sclerotherapy for treatment of venous malformations (VMs) of the face, head and neck. It is our hope that data from this study could be used to better inform providers and patients regarding the benefits and risks of percutaneous sclerotherapy for treatment of face, head and neck VMs. We searched PubMed, MEDLINE, and EMBASE from 2000–2018 for studies evaluating the safety and efficacy of percutaneous sclerotherapy of neck, face and head VMs. Two independent reviewers selected studies and abstracted data. The primary outcomes were complete and partial resolution of the VM. Data were analyzed using random-effects meta-analysis. Thirty-seven studies reporting on 2,067 patients were included. The overall rate of complete cure following percutaneous sclerotherapy with any agent was 64.7% (95% confidence interval [CI], 57.4–72.0%). Sodium tetradecyl sulfate had the lowest complete cure rate at 55.5% (95% CI, 36.1–74.9%) while pingyangmycin had the highest cure rate at 82.9% (95% CI, 71.1–94.7%). Overall patient satisfaction rates were 91.0% (95% CI, 86.1–95.9%). Overall quality of life improvement was 78.9% (95% CI, 67.0–90.8%). Overall permanent morbidity/mortality was 0.8% (95% CI, 0.3–1.3%) with no cases of mortality. Our systematic review and meta-analysis of 37 studies and over 2,000 patients found that percutaneous sclerotherapy is a very safe and effective treatment modality for treatment of VMs of the head, neck and face.

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Percutaneous Sclerotherapy of Venous Malformations of the Head and Neck Using Sodium Tetradecyl Sulphate (Sotradecol)

Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery ◽

10.3109/02844319709085481 ◽

1997 ◽

Vol 31 (2) ◽

pp. 145-150 ◽

Cited By ~ 92

Author(s):

Topi M. J. Siniluoto ◽

Paul A. Svendsen ◽

Gunnar M. Wikholm ◽

Ingemar Fogdestam ◽

Staffan Edström

Keyword(s):

Head And Neck ◽

Venous Malformations ◽

Percutaneous Sclerotherapy ◽

Sodium Tetradecyl Sulphate

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Ethanol sclerotherapy of head and neck venous malformations

Einstein (São Paulo) ◽

10.1590/s1679-45082014ao2844 ◽

2014 ◽

Vol 12 (2) ◽

pp. 181-186 ◽

Cited By ~ 14

Author(s):

José Luiz Orlando ◽

José Guilherme Mendes Pereira Caldas ◽

Heloisa Galvão do Amaral Campos ◽

Kenji Nishinari ◽

Mariana Krutman ◽

...

Keyword(s):

Head And Neck ◽

Complete Resolution ◽

Intralesional Injection ◽

Low Doses ◽

Venous Malformations ◽

Ethanol Sclerotherapy ◽

Percutaneous Sclerotherapy ◽

Effective Treatment Modality ◽

Median Period ◽

The Face

Objective This retrospective study evaluated the results of sclerotherapy with low doses of ethanol for treatment of head and neck venous malformations.Methods We treated 51 patients, 37 females. Median age was 23 years. Patients were treated with percutaneous intralesional injection of alcohol every two weeks and followed up prospectively for a median period of 18 months. Most lesions affected the face and cosmetic disfigurement was the most frequent complaint.Results We performed a median of 7 sessions of sclerotherapy. Complete resolution or improvement was observed in 48 patients presented. Five cases of small skin ulceration, two cases of hyperpigmentation and two of paresthesia were documented; all of them were treated conservatively.Conclusion Percutaneous sclerotherapy with low doses of ethanol is a safe and effective treatment modality for venous malformations affecting the head and neck.

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