scholarly journals Ethanol sclerotherapy of head and neck venous malformations

2014 ◽  
Vol 12 (2) ◽  
pp. 181-186 ◽  
Author(s):  
José Luiz Orlando ◽  
José Guilherme Mendes Pereira Caldas ◽  
Heloisa Galvão do Amaral Campos ◽  
Kenji Nishinari ◽  
Mariana Krutman ◽  
...  
Keyword(s):  
Head And Neck ◽  
Complete Resolution ◽  
Intralesional Injection ◽  
Low Doses ◽  
Venous Malformations ◽  
Ethanol Sclerotherapy ◽  
Percutaneous Sclerotherapy ◽  
Effective Treatment Modality ◽  
Median Period ◽  
The Face

Objective This retrospective study evaluated the results of sclerotherapy with low doses of ethanol for treatment of head and neck venous malformations.Methods We treated 51 patients, 37 females. Median age was 23 years. Patients were treated with percutaneous intralesional injection of alcohol every two weeks and followed up prospectively for a median period of 18 months. Most lesions affected the face and cosmetic disfigurement was the most frequent complaint.Results We performed a median of 7 sessions of sclerotherapy. Complete resolution or improvement was observed in 48 patients presented. Five cases of small skin ulceration, two cases of hyperpigmentation and two of paresthesia were documented; all of them were treated conservatively.Conclusion Percutaneous sclerotherapy with low doses of ethanol is a safe and effective treatment modality for venous malformations affecting the head and neck.

scholarly journals Sclerotherapy for Venous Malformations of Head and Neck: Systematic Review and Meta-Analysis

2020 ◽  
Vol 15 (1) ◽  
pp. 4-17 ◽  
Author(s):  
Lucio De Maria ◽  
Paolo De Sanctis ◽  
Karthik Balakrishnan ◽  
Megha Tollefson ◽  
Waleed Brinjikji
Keyword(s):  
Systematic Review ◽  
Head And Neck ◽  
Meta Analysis ◽  
Venous Malformations ◽  
Cure Rate ◽  
Complete Cure ◽  
Percutaneous Sclerotherapy ◽  
Effective Treatment Modality ◽  
The Face ◽  
Life Improvement

We performed a systematic review and meta-analysis of studies performing sclerotherapy for treatment of venous malformations (VMs) of the face, head and neck. It is our hope that data from this study could be used to better inform providers and patients regarding the benefits and risks of percutaneous sclerotherapy for treatment of face, head and neck VMs. We searched PubMed, MEDLINE, and EMBASE from 2000–2018 for studies evaluating the safety and efficacy of percutaneous sclerotherapy of neck, face and head VMs. Two independent reviewers selected studies and abstracted data. The primary outcomes were complete and partial resolution of the VM. Data were analyzed using random-effects meta-analysis. Thirty-seven studies reporting on 2,067 patients were included. The overall rate of complete cure following percutaneous sclerotherapy with any agent was 64.7% (95% confidence interval [CI], 57.4–72.0%). Sodium tetradecyl sulfate had the lowest complete cure rate at 55.5% (95% CI, 36.1–74.9%) while pingyangmycin had the highest cure rate at 82.9% (95% CI, 71.1–94.7%). Overall patient satisfaction rates were 91.0% (95% CI, 86.1–95.9%). Overall quality of life improvement was 78.9% (95% CI, 67.0–90.8%). Overall permanent morbidity/mortality was 0.8% (95% CI, 0.3–1.3%) with no cases of mortality. Our systematic review and meta-analysis of 37 studies and over 2,000 patients found that percutaneous sclerotherapy is a very safe and effective treatment modality for treatment of VMs of the head, neck and face.

Absolute Ethanol Sclerotherapy for Venous Malformations in the Face and Neck

2010 ◽  
Vol 68 (7) ◽  
pp. 1622-1627 ◽  
Author(s):  
Lixin Su ◽  
Xindong Fan ◽  
Lianzhou Zheng ◽  
Jiawei Zheng
Keyword(s):  
Absolute Ethanol ◽  
Venous Malformations ◽  
Ethanol Sclerotherapy ◽  
The Face

Dose-saving isolation procedure in percutaneous ethanol sclerotherapy for venous malformations

2013 ◽  
Vol 29 (5) ◽  
pp. 276-286 ◽  
Author(s):  
K Kishi ◽  
N Morita ◽  
T Terada ◽  
M Sato
Keyword(s):  
Clinical Outcome ◽  
Head And Neck ◽  
Unit Area ◽  
Injection Sclerotherapy ◽  
Venous Malformations ◽  
Isolation Technique ◽  
Ethanol Injection ◽  
Ethanol Dose ◽  
Ethanol Sclerotherapy ◽  
The Mean

Objectives: To evaluate the feasibility and effectiveness of an isolation technique during ethanol injection sclerotherapy for venous malformations (VMs) in the head and neck region. Methods: The subjects were 23 patients with 35 VM lesions in the head and neck, treated between 1999 and 2012. The mean lesion area was 3.75 ± 3.09 cm2 (± standard deviation). We confirmed the contour of the lesions to be treated on a fully filled image on direct injection cisternography, and observed patterns of communicating drainage to systemic veins. The cisterns were evacuated by squeezing and were isolated by manual compression of the communicators. Ethanol (94.5%) with a contrast agent was then injected into both isolable and unisolable lesions, up to a total volume of 1 mL/cm2, avoiding complications. We investigated the relationship between lesion size and injected ethanol dose, and also dose per unit area. Results: Both manual evacuation by compression and isolation were performed in 20 (57.1%) isolable lesions, but not in 15 unisolable lesions. The mean injected ethanol dose was 0.65 ± 0.31 mL/cm2 overall, 0.70 ± 0.32 in isolable and 0.59 ± 0.30 in unisolable lesions (NS). However, the injected ethanol dose was significantly lower for lesions sized >6 cm. Complete to near-complete shrinkage was observed in all isolable lesions, and in 60% of unisolable lesions ( P < 0.05). Clinical outcome seemed unrelated to the injected ethanol dose or the dose per unit area. There was one case of recurrence and one complication in the unisolable lesions. No further relapses or complications were observed during the follow-up period of 38.6 ± 12.3 months. Conclusions: Clinical outcome was related to the isolability not to the injected dose. The isolation appears useful for improving the safety and effectiveness of ethanol sclerotherapy for VM.

Percutaneous sclerotherapy with ethanolamine oleate for venous malformations of the head and neck

2013 ◽  
Vol 6 (9) ◽  
pp. 695-698 ◽  
Author(s):  
Matthew David Alexander ◽  
Ryan A McTaggart ◽  
Omar A Choudhri ◽  
Mary L Marcellus ◽  
Huy M Do
Keyword(s):  
Head And Neck ◽  
Venous Malformations ◽  
Ethanolamine Oleate ◽  
Percutaneous Sclerotherapy

scholarly journals Multiple Venous Malformations with Phleboliths: Radiological-Pathological Correlation

2013 ◽  
Vol 3 ◽  
pp. 13 ◽  
Author(s):  
Venkateswara Rao Chava ◽  
Ashwini Naveen Shankar ◽  
Naveen Shankar Vemanna ◽  
Sudheer Kumar Cholleti
Keyword(s):  
Head And Neck ◽  
Clinical Symptoms ◽  
Vascular Malformations ◽  
High Flow ◽  
The Body ◽  
Low Flow ◽  
Venous Malformations ◽  
Congenital Lesions ◽  
The Face ◽  
Histopathologic Findings

Vascular malformations are congenital lesions that are present at birth and do not regress. However, they often present later in life. They are subdivided into two categories: (1) slow- or low-flow and (2) fast- or high-flow malformations. Low-flow malformations contain combinations of capillary, venous, and lymphatic components. Venous malformations can occur anywhere in the body, but are most frequently seen in the head and neck (40%). These lesions present in a variety of ways, from a vague blue patch to a soft blue mass, which may be single isolated or may occur in multiple areas. Treatment depends on the type of lesion, the location, degree of involvement, and the clinical symptoms. Here we are report the imaging and histopathologic findings in a patient with multiple venous malformations affecting the left side of the face and trunk.

scholarly journals Image-guided percutaneous sclerotherapy of venous malformations of the head and neck: Clinical and MR-based volumetric mid-term outcome

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0241347
Author(s):  
Dominik F. Vollherbst ◽  
Philipp Gebhart ◽  
Steffen Kargus ◽  
Astrid Burger ◽  
Reinald Kühle ◽  
...  
Keyword(s):  
Head And Neck ◽  
Venous Malformations ◽  
Term Outcome ◽  
Image Guided ◽  
Percutaneous Sclerotherapy
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