Central venous thrombosis in patients receiving long-term parenteral nutrition

2008 ◽  
Vol 33 (1) ◽  
pp. 32-38 ◽  
Author(s):  
Donald R. Duerksen
Keyword(s):  
Parenteral Nutrition ◽  
Venous Thrombosis ◽  
Vitamin K ◽  
Central Venous Access ◽  
Anticoagulation Therapy ◽  
Venous Catheter ◽  
Venous Access ◽  
Central Venous ◽  
Central Venous Thrombosis

Long-term parenteral nutrition (PN) is administered to patients who are unable to use their gastrointestinal tract to absorb sufficient nutrients and water to maintain their nutritional status. Patients receiving long-term parenteral nutrition are at risk of numerous complications including thrombosis of the central venous catheter used to provide nutrition. Central venous access is essential to the successful delivery of long-term PN. One of the strategies to lessen the frequency of this complication is anticoagulation therapy with warfarin. The effect of warfarin in preventing this complication may be modified by vitamin K intake. Individuals with gastrointestinal failure may receive vitamin K from a variety of sources. This review summarizes the role of warfarin in preventing central venous access thrombosis. It also summarizes potential sources of vitamin K intake in home parenteral nutrition patients, examines the evidence for recommendations regarding vitamin K intake, and considers the potential impact of increased vitamin K intake on home PN patients, particularly on the prevention of central venous thrombosis.

Catheter-Related Central Venous Thrombosis: The Development of a Nationwide Consensus Paper in Italy

2007 ◽  
Vol 12 (1) ◽  
pp. 38-46 ◽  
Author(s):  
Costantino Campisi ◽  
Roberto Biffi ◽  
Mauro Pittiruti ◽  
Keyword(s):  
Venous Thrombosis ◽  
Health Professionals ◽  
Central Venous Access ◽  
Venous Access ◽  
Scientific Data ◽  
Consensus Meeting ◽  
Study Group ◽  
Central Venous ◽  
Central Venous Thrombosis

Abstract Catheter-related central venous thrombosis is a serious complication in patients who need long-term venous access. Though scientific data and clinical experience are steadily increasing, many uncertainties still exist about several aspects of this complication, including etiology, pathogenesis, diagnosis, management, and prevention of this complication. The GAVeCeLT (the Italian Study Group for Long Term Central Venous Access) promoted a nationwide consensus, and 12 experts reviewed systematically all the available literature. A preliminary document was presented and discussed during a specific Consensus Meeting, in front of a panel of more than 80 experts (representing different health professions and disciplines). This led to a prefinal document, which was presented to more than 800 health professionals. After peer review by an external board of experts, the final document was prepared. In this article, methodology and results of the consensus are presented.

Tip Position of Long-Term Central Venous Access Devices Used for Parenteral Nutrition

2007 ◽  
Vol 31 (5) ◽  
pp. 382-387 ◽  
Author(s):  
Robert DeChicco ◽  
Douglas L. Seidner ◽  
Carlos Brun ◽  
Ezra Steiger ◽  
Judy Stafford ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Central Venous Access ◽  
Venous Access ◽  
Central Venous ◽  
Tip Position ◽  
Venous Access Devices

scholarly journals Vias para Nutrição Artificial na Criança (II): Acessos Parentéricos

2014 ◽  
Vol 27 (6) ◽  
pp. 767
Author(s):  
José Estevão-Costa
Keyword(s):  
Parenteral Nutrition ◽  
Central Venous Catheterization ◽  
Venous Catheter ◽  
Venous Access ◽  
The Body ◽  
Central Catheter ◽  
Maintenance Care ◽  
Central Venous ◽  
Venous Catheterization

Parenteral nutrition is crucial when the use of the gastrointestinal tract is not feasible. This article addresses the main techniques for parenteral access in children, its indications, insertion details and maintenance, and complications. The type of venous access is mainly dictated by the expected duration of parenteral nutrition and by the body weight/stature. The peripheral access is viable and advantageous for parenteral nutrition of short duration (&lt; 2 weeks); a tunneled central venous catheter (Broviac) is usually necessary in long-term parenteral nutrition (&gt; 3 weeks); a peripherally introduced central catheter is an increasingly used alternative. Parenteral<br />accesses are effective and safe, but the morbidity and mortality is not negligible particularly in cases of short bowel syndrome. Most complications are related to the catheter placement and maintenance care, and can be largely avoided when the procedures are carried out by experienced staff under strict protocols.<br /><strong>Keywords:</strong> Child; Parenteral Nutrition; Catheterization, Central Venous; Catheterization, Peripheral.

scholarly journals Central Venous Access with Occlusive Superior Central Venous Thrombosis

1986 ◽  
Vol 203 (1) ◽  
pp. 30-33 ◽  
Author(s):  
MICHAEL H. TOROSIAN ◽  
STEVEN MERANZE ◽  
JAMES L. MULLEN ◽  
GORDON MCLEAN
Keyword(s):  
Venous Thrombosis ◽  
Central Venous Access ◽  
Venous Access ◽  
Central Venous ◽  
Central Venous Thrombosis

Thrombosis and embolism in long-term central venous access for parenteral nutrition

The Lancet ◽  
1994 ◽  
Vol 344 (8929) ◽  
pp. 1043-1045 ◽  
Author(s):  
C.M Dollery ◽  
I.D Sullivan ◽  
C Bull ◽  
O Bauraind ◽  
P.J Milla
Keyword(s):  
Parenteral Nutrition ◽  
Central Venous Access ◽  
Venous Access ◽  
Central Venous

scholarly journals Non-Antibiotic Antimicrobial Catheter Lock Solutions in Patients on Home Parenteral Nutrition

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1165 ◽  
Author(s):  
Jessica Noelting ◽  
Brian Jurewitsch ◽  
Johane Allard
Keyword(s):  
Parenteral Nutrition ◽  
Central Venous Access ◽  
Bloodstream Infections ◽  
Venous Access ◽  
Home Parenteral Nutrition ◽  
Microbial Colonization ◽  
Central Venous ◽  
New Methods ◽  
Catheter Lock

Patients on home parenteral nutrition (HPN) are dependent on central venous access for long-term sustenance, and catheter-related bloodstream infections (CRBSIs) are a major cause of morbidity and mortality in this patient population. As such, there is much interest in finding new methods for preventing CRBSIs in patients on HPN. As it is thought that these infections are preceded by microbial colonization of the catheter, one approach is to use antimicrobial catheter lock solutions. Although antibiotic catheter lock solutions have been present for decades, their use has been mostly limited to the treatment of CRBSIs due to concern for promoting microbial resistance. Recently, however, with the advent of non-antibiotic antimicrobial catheter lock solutions, this approach is gaining popularity as a promising method to decrease rates of CRBSI in HPN patients.

Central venous thrombosis in children with intestinal failure on long-term parenteral nutrition

2016 ◽  
Vol 51 (5) ◽  
pp. 790-793 ◽  
Author(s):  
Jessica Gonzalez-Hernandez ◽  
Yahya Daoud ◽  
Jennifer Styers ◽  
Janna M. Journeycake ◽  
Nandini Channabasappa ◽  
...  
Keyword(s):  
Parenteral Nutrition ◽  
Venous Thrombosis ◽  
Intestinal Failure ◽  
Central Venous ◽  
Central Venous Thrombosis

scholarly journals Updates in Parenteral Nutrition

2014 ◽  
Vol 21 (3) ◽  
pp. 213-219
Author(s):  
Simona Popescu ◽  
Laura Diaconu ◽  
Bogdan Timar ◽  
Romulus Timar
Keyword(s):  
Amino Acids ◽  
Parenteral Nutrition ◽  
Nutritional Support ◽  
Laboratory Tests ◽  
Central Venous Access ◽  
Venous Access ◽  
Peripheral Vein ◽  
Central Venous ◽  
Additional Approach

AbstractParenteral nutrition (PN) represents an alternative or additional approach when other nutrition routes are not succeeding or when using other routes is not possible or would be unsafe. The main goal of PN is to deliver a nutrient mixture closely related to requirements in a safe manner and without complications. The concentration of parenteral solutions (PS) determines their osmolarity, according to which, the solutions will be infused by peripheral or central venous access. The solutions used in central PN contain more glucose, which, together with amino acids and electrolytes, determines a hyperosmolar solution, which has to be administered in a large caliber vein. Central venous access may be maintained over long periods of time. In peripheral PN there are used solutions with a lower concentration of dextrose in order to obtain (solutions with the) an osmolarity lower than 900 mOsm/L, which can be administered in a peripheral vein. Peripheral PN is used over short periods of time because of the limited tolerance for a long term of peripheral veins. PN is an efficient method to ensure the nutritional support which can be associated with numerous complications, some of them severe, with lethal potential. Patients with PN need a daily physical examination and laboratory tests.

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