An improved synthesis of m-diazirinophenol
Keyword(s):
The published synthesis of phenolic diazirine was shown to result in products which were chlorinated during the hypochlorite oxidation while the desired unchlorinated product was lost during the usual work-up. A superior synthesis is described: inclusion of pyridine during the oxidation step prevents the chlorination; the desired volatile diazirine was isolated in good yield using silica gel and reverse phase high pressure liquid chromatography.
1984 ◽
Vol 139
(1)
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pp. 68-74
1977 ◽
Vol 60
(2)
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pp. 272-278
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1976 ◽
Vol 59
(5)
◽
pp. 989-992
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1979 ◽
Vol 16
(1-6)
◽
pp. 213-216
◽
1984 ◽
Vol 802
(1)
◽
pp. 29-40
◽
Keyword(s):