EXPERIMENTAL INVESTIGATION OF POSTSTENOTIC DILATATION IN ISOLATED ARTERIES

1964 ◽  
Vol 42 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Margot R. Roach ◽  
Kenneth Harvey

Isolated human and dog iliac arteries were mounted in a double-chambered plethysmograph and perfused with merthiolate solution. Various degrees of stenosis were produced by plastic rings. Only arteries with moderate stenoses (i.e. those that produced a distal thrill and bruit) developed poststenotic dilatation, but all of them did. The dilatation usually started within 5 minutes, progressed rapidly for 20 to 30 minutes, and then more slowly for up to 3 days. Pressure–volume measurements showed that the dilated segment was more distensible than normal.

1975 ◽  
Vol 53 (6) ◽  
pp. 998-1004 ◽  
Author(s):  
Raymond Vito ◽  
W. K. Tso ◽  
Colin J. Schwartz

A study of the relationship between the mechanical response of human iliac arteries subjected to sinusoidally varying dynamic pressures superimposed on a static pressure of 100 mm Hg(1 mm Hg = 133 N/m2) and the development of arterial dilatation, with particular reference to poststenotic dilatation, has been conducted. In 13 experiments, optical measurements of the amplitude of vessel wall movements in response to dynamic pressures of amplitude 5 mm Hg peak to peak indicated the presence of at least one, and at most four resonance peaks for frequencies in the range 0–100 Hz. Four specimens were vibrated at resonance and four at frequencies 15 Hz higher than resonance, in response to a dynamic pressure of 5 mm Hg peak to peak for 3 h. All specimens exhibited some dilatation, the average percentage increase in diameter being in the range 0.22 to 0.42% per hour. In four additional experiments, the dynamic pressure was doubled at constant frequency. This resulted in an increased amplitude of vibration and additional dilatation at an increased rate. It is concluded that the dynamic stresses present in the vessel influence the rate of dilatation.


2007 ◽  
Vol 177 (4S) ◽  
pp. 122-122
Author(s):  
Stephen A. Poon ◽  
G. Joel DeCastro ◽  
Carl K. Gjertson ◽  
Kenneth I. Glassberg

2014 ◽  
Author(s):  
Shane Close ◽  
Victoria Adkins ◽  
Kandice Perry ◽  
Katheryn Eckles ◽  
Jill Brown ◽  
...  

2004 ◽  
Author(s):  
Mustapha Mouloua ◽  
Janan Smither ◽  
Robert C. Kennedy ◽  
Robert S. Kenned ◽  
Dan Compton ◽  
...  

2013 ◽  
Author(s):  
Sarah Edwards ◽  
Lindsey Brinker ◽  
Kathryn A. Bradshaw ◽  
Jennifer A. Munch ◽  
Rachel E. Brenner

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