Study and analysis of motion artifacts for ambulatory electroencephalography

Motion artifacts contribute complexity in acquiring clean electroencephalography (EEG) data. It is one of the major challenges for ambulatory EEG. The performance of mobile health monitoring, neurological disorders diagnosis and surgeries can be significantly improved by reducing the motion artifacts. Although different papers have proposed various novel approaches for removing motion artifacts, the datasets used to validate those algorithms are questionable. In this paper, a unique EEG dataset was presented where ten different activities were performed. No such previous EEG recordings using EMOTIV EEG headset are available in research history that explicitly mentioned and considered a number of daily activities that induced motion artifacts in EEG recordings. Quantitative study shows that in comparison to correlation coefficient, the coherence analysis depicted a better similarity measure between motion artifacts and motion sensor data. Motion artifacts were characterized with very low frequency which overlapped with the Delta rhythm of the EEG. Also, a general wavelet transform based approach was presented to remove motion artifacts. Further experiment and analysis with more similarity metrics and longer recording duration for each activity is required to finalize the characteristics of motion artifacts and henceforth reliably identify and subsequently remove the motion artifacts in the contaminated EEG recordings.

Chewing gum reduces visually induced motion sickness

Visually induced motion sickness (VIMS) is a common side-effect of exposure to virtual reality (VR). Its unpleasant symptoms may limit the acceptance of VR technologies for training or clinical purposes. Mechanical stimulation of the mastoid and diverting attention to pleasant stimuli-like odors or music have been found to ameliorate VIMS. Chewing gum combines both in an easy-to-administer fashion and should thus be an effective countermeasure against VIMS. Our study investigated whether gustatory-motor stimulation by chewing gum leads to a reduction of VIMS symptoms. 77 subjects were assigned to three experimental groups (control, peppermint gum, and ginger gum) and completed a 15-min virtual helicopter flight, using a VR head-mounted display. Before and after VR exposure, we assessed VIMS with the Simulator Sickness Questionnaire (SSQ), and during the virtual flight once every minute with the Fast Motion Sickness Scale (FMS). Chewing gum (peppermint gum: M = 2.44, SD = 2.67; ginger gum: M = 2.57, SD = 3.30) reduced the peak FMS scores by 2.05 (SE = 0.76) points as compared with the control group (M = 4.56, SD = 3.52), p < 0.01, d = 0.65. Additionally, taste ratings correlated slightly negatively with both the SSQ and the peak FMS scores, suggesting that pleasant taste of the chewing gum is associated with less VIMS. Thus, chewing gum may be useful as an affordable, accepted, and easy-to-access way to mitigate VIMS in numerous applications like education or training. Possible mechanisms behind the effect are discussed.

A case for glycerol as an acceptable additive for single-particle cryoEM samples

Buffer-composition and sample-preparation guidelines for cryo-electron microscopy are geared towards maximizing imaging contrast and reducing electron-beam-induced motion. These pursuits often involve the minimization or the complete removal of additives that are commonly used to facilitate proper protein folding and minimize aggregation. Among these admonished additives is glycerol, a widely used osmolyte that aids protein stability. In this work, it is shown that the inclusion of glycerol does not preclude high-resolution structure determination by cryoEM, as demonstrated by an ∼2.3 Å resolution reconstruction of mouse apoferritin (∼500 kDa) and an ∼3.3 Å resolution reconstruction of rabbit muscle aldolase (∼160 kDa) in the presence of 20%(v/v) glycerol. While it was found that generating thin ice that is amenable to high-resolution imaging requires long blot times, the addition of glycerol did not result in increased beam-induced motion or an inability to pick particles. Overall, these findings indicate that glycerol should not be discounted as a cryoEM sample-buffer additive, particularly for large, fragile complexes that are prone to disassembly or aggregation upon its removal.

Simulation and Virtual Reality Using Nonlinear Kinematic Parameters as a Means of Predicting Motion Sickness in Real-Time in Virtual Environments

Objective This article presents two studies (one simulation and one pilot) that assess a custom computer algorithm designed to predict motion sickness in real-time. Background Virtual reality has a wide range of applications; however, many users experience visually induced motion sickness. Previous research has demonstrated that changes in kinematic (behavioral) parameters are predictive of motion sickness. However, there has not been research demonstrating that these measures can be utilized in real-time applications. Method Two studies were performed to assess an algorithm designed to predict motion sickness in real-time. Study 1 was a simulation study that used data from Smart et al. (2014). Study 2 employed the algorithm on 28 new participants’ motion while exposed to virtual motion. Results Study 1 revealed that the algorithm was able to classify motion sick participants with 100% accuracy. Study 2 revealed that the algorithm could predict if a participant would become motion sick with 57% accuracy. Conclusion The results of the present study suggest that the motion sickness prediction algorithm can predict if an individual will experience motion sickness but needs further refinement to improve performance. Application The algorithm could be used for a wide array of VR devices to predict likelihood of motion sickness with enough time to intervene.

Oscillatory Motion of Viscoelastic Drops on Slippery Lubricated Surfaces

The introduction of slippery lubricated surfaces allows the investigation of the flow of highly viscous solutions which otherwise will hardly move on standard solid surfaces. Here we present the study of the gravity induced motion of small viscoelastic drops deposited on inclined lubricated surfaces. The viscoelastic fluids exhibit shear thinning and, more importantly, a significant first normal stress difference N1. Despite the homogeneity of the surface and of the fluids, drops of sufficiently high N1 move down with an oscillating instantaneous speed whose frequency is found to be directly proportional to the average speed and inversely to the drop volume. The oscillatory motion is caused by the formation of a bulge at the drop rear that starts rolling around the moving drop.

Thermal Cooling Enhancements in a Heated Channel Using Flow-Induced Motion

The paper presents the comparative study of the vortex-induced cooling of a heated channel for the four different cross-sections of the rigid cylinder, i.e., circular, square, semi-circular, and triangular, with or without the rigid/flexible splitter plate at the Reynolds number (based on the hydraulic diameter) of 200. The study presents a comprehensive analysis of the flow and thermal performance for all the cases. For flexible plate cases, a partitioned approach is invoked to solve the coupled fluid-structure-convection problem. The simulations show the reduction in the thermal boundary layer thickness at the locations of the vortices resulting in the improved Nusselt number. Further, the thin plate's flow-induced motion significantly increases the vorticity field inside the channel, resulting in improved mixing and cooling. It is observed that the plate-motion amplitude is maximum when the plate is attached to the cylinder with the triangular cross-section. The power requirement analysis shows that the flexible plate reduces the power required to pump the channel's cold fluid. Thus, based on the observations of the present study, the authors recommend using the flexible plate attached to the cylinder for improved convective cooling.