Failure of Human Growth Hormone and Human Placental Lactogen to Affect Glucose Consumption by Human Erythrocytes and Leucocytes In Vitro

1972 ◽  
Vol 50 (10) ◽  
pp. 1014-1017
Author(s):  
Catherine L. Tanser ◽  
Nannie K. M. de Leeuw
Keyword(s):  
Growth Hormone ◽  
Glucose Oxidase ◽  
Human Growth Hormone ◽  
Glucose Utilization ◽  
Human Growth ◽  
Glucose Consumption ◽  
Inhibitory Effect ◽  
Placental Lactogen ◽  
Human Placental Lactogen

The effect of human growth hormone (HGH) and human placental lactogen (HPL) on glucose consumption by erythrocytes and leucocytes in vitro was investigated. Glucose consumption was measured by determining glucose utilization during 3 h incubation at 37 °C, using the glucose oxidase method.HGH and HPL showed no effect on glucose consumption by erythrocytes, and HPL showed no effect on glucose consumption by leucocytes in vitro. Our results do not confirm previous reports of an inhibitory effect of HGH on glucose consumption by erythrocytes in vitro.

scholarly journals Recombinant hormones from fragments of human growth hormone and human placental lactogen.

1981 ◽  
Vol 256 (1) ◽  
pp. 296-300
Author(s):  
J. Russell ◽  
L.M. Sherwood ◽  
K. Kowalski ◽  
A.B. Schneider
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Placental Lactogen ◽  
Human Placental Lactogen

RESPONSE OF CHONDROCYTES ISOLATED FROM HUMAN FOETAL CARTILAGE TO PLASMA SOMATOMEDIN ACTIVITY

1978 ◽  
Vol 76 (3) ◽  
pp. 473-477 ◽  
Author(s):  
I. K. ASHTON ◽  
M. J. O. FRANCIS
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Thymidine Incorporation ◽  
Human Growth ◽  
Placental Lactogen ◽  
Human Placental Lactogen ◽  
Direct Effects

Plasma somatomedin activity enhanced the incorporation of [3H]thymidine into chondrocytes isolated from human foetal cartilage during weeks 13–21 of gestation. Human growth hormone (0·1–20 μu./ml), human placental lactogen (0·1–5 μg/ml) and insulin (0·25– 10 μu./ml) had no direct effects on the synthesis of DNA in these chondrocytes, although insulin at concentrations of 2·5–100 mu./ml increased [3H]thymidine incorporation by up to 400%.

Measurement of Human Growth Hormone in Pregnancy and Correlation with Human Placental Lactogen

1971 ◽  
Vol 32 (3) ◽  
pp. 328-332 ◽  
Author(s):  
SURENDRA K. VARMA ◽  
PETER H. SONKSEN ◽  
KAMLESH VARMA ◽  
J. STUART SOELDNER ◽  
HERBERT A. SELENKOW ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Placental Lactogen ◽  
Human Placental Lactogen ◽  
In Pregnancy

In vitro Inhibition of Erythrocyte Glucose Consumption by Human Growth Hormone

Nature ◽  
1967 ◽  
Vol 215 (5096) ◽  
pp. 81-82 ◽  
Author(s):  
FRANK A. OSKI ◽  
ALLEN ROOT ◽  
ALBERT I. WINEGRAD
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Growth ◽  
Glucose Consumption ◽  
In Vitro Inhibition
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