Phenobarbitone-induced urinary excretions of D-glucaric acid and 6β-hydroxycortisol in man
1976 ◽
Vol 54
(5)
◽
pp. 778-782
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Keyword(s):
The urinary excretions of D-glucaric acid and 6β-hydroxycortisol were determined in normal subjects before, during, and after 14 days treatment with placebo or phenobarbitone. The excretion of both metabolites was significantly potentiated by phenobarbitone and returned to baseline values 1 month after treatment was withdrawn. It was suggested that the determination of urinary D-glucaric acid reflects the activity of the hepatic microsomal mixed function oxidase system after the administration of an inducing agent such as phenobarbitone.
1986 ◽
Vol 9
(1)
◽
pp. 67-73
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1997 ◽
Vol 118
(3)
◽
pp. 301-304
◽
1976 ◽
Vol 444
(2)
◽
pp. 613-617
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2009 ◽
Vol 43
(1)
◽
pp. 6-12
◽
1978 ◽
Vol 2
(4)
◽
pp. 727-749
1982 ◽
Vol 20
(4)
◽
pp. 407-412
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