scholarly journals Activity-induced instabilities of brain organoids

2021 ◽  
Vol 44 (12) ◽  
Author(s):  
Kristian Thijssen ◽  
Guido L. A. Kusters ◽  
Amin Doostmohammadi

AbstractWe present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to explain the experimental observation of surface instabilities in brain organoids, the role of activity has been largely overlooked. Our results show that the active stress generated by the cells can be a, previously overlooked, contributor to the emergence of surface deformations in brain organoids.

2021 ◽  
Author(s):  
R. Supreeth ◽  
A. Arokkiaswamy ◽  
Anirudh Keshavan ◽  
Pradyumna R. Koushik ◽  
Pramod P. Kashyap ◽  
...  

2005 ◽  
Author(s):  
Michael Fehler ◽  
Lianjie Huang ◽  
Ru‐Shan Wu ◽  
Xiao‐Bi Xie

2020 ◽  
Vol 29 (09) ◽  
pp. 2050073
Author(s):  
Sven Åberg ◽  
Akhilesh Yadav ◽  
A. Shukla

Experimental observation of [Formula: see text]Si as a proton bubble nuclei has heated up the interest in the study of exotic bubble shaped nuclei. In this work, some of the potential doubly bubble-like (for proton as well as neutron both simultaneously) cases have been explored using relativistic Hartree–Bogoliubov (RHB) in light mass region, specially around N or [Formula: see text]. Further, the role of pairing and the evolution of new shell gaps around [Formula: see text] or [Formula: see text] and 34 have been investigated, as one moves toward drip lines. This study suggests that the occupancies/vacancies of neutron/proton orbitals for lower angular momentum state plays major role in nuclear structure to create bubble-like structure and [Formula: see text]O[Formula: see text], [Formula: see text]Mg8 and [Formula: see text]Si[Formula: see text] may have dual bubble-like structures.


2020 ◽  
Vol 27 (2) ◽  
pp. 022101 ◽  
Author(s):  
Mohamad Menati ◽  
Behnam Rasoolian ◽  
Edward Thomas ◽  
Uwe Konopka

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