CHARACTERIZATION OF THE PULSED NEEDLE-FREE MICRO-INJECTOR IN THE MEDICAL DELIVERY SYSTEM

2009 ◽  
Vol 23 (03) ◽  
pp. 393-396 ◽  
Author(s):  
MUH-RONG WANG ◽  
CHUN-HSIEN CHIU
Keyword(s):  
Injection System ◽  
The Novel ◽  
Penetration Test ◽  
Tumor Treatment ◽  
Liquid Pressure ◽  
Solid Materials ◽  
Injection Power ◽  
Pulsed Injection ◽  
Medical Delivery

This paper describes the development of the needle-free injection with a pulsed micro-injector. The novel injection system consists of a micro-injector, a solenoid valve with an electron-control system and a high pressure liquid supply system. The diameters of the orifice are 200µm~ 300µm. The performance of both pulsed and continuous injections is characterized. Results show that the mass flow rate is increased linearly for the liquid pressure ranging from 50bar to 125bar. The jet velocity increases from 50.6m/s to 104m/s as the liquid pressure increases from 50bar to 125bar. Penetration test to the soft solid materials shows that the penetration depth is increased from 2mm to 7mm depending on the injection power under single pulsed injection. It is believed that the technique will be useful for the drug delivery as well as the localized tumor treatment.

Characterization of the novel HLA‐C *07:944 allele by next‐generation sequencing

HLA ◽  
2021 ◽  
Author(s):  
Maria Loginova ◽  
Olga Makhova ◽  
Daria Smirnova ◽  
Igor Paramonov ◽  
Maksim Zarubin
Keyword(s):  
Next Generation Sequencing ◽  
The Novel ◽  
Next Generation ◽  
Generation Sequencing

Characterization of the novel HLA‐B *51:296 allele by next‐generation sequencing

HLA ◽  
2020 ◽  
Author(s):  
Steve Genebrier ◽  
Vincent Elsermans ◽  
Emeric Texeraud ◽  
Gerald Bertrand ◽  
Virginie Renac
Keyword(s):  
Next Generation Sequencing ◽  
The Novel ◽  
Next Generation ◽  
Generation Sequencing

Characterization of the novel HLA‐DRB1*11:282 allele by sequencing‐based typing

HLA ◽  
2021 ◽  
Author(s):  
Marine Cargou ◽  
Vincent Elsermans ◽  
Isabelle Top ◽  
Laura Blouin ◽  
Jonathan Visentin
Keyword(s):  
The Novel

scholarly journals Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04

Viruses ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 27
Author(s):  
Jun Kwon ◽  
Sang Guen Kim ◽  
Hyoun Joong Kim ◽  
Sib Sankar Giri ◽  
Sang Wha Kim ◽  
...  
Keyword(s):  
Morphological Traits ◽  
Open Reading Frames ◽  
Genome Comparison ◽  
The Novel ◽  
Promising Alternative ◽  
Isolation And Characterization ◽  
Global Issue ◽  
Reading Frames ◽  
Predicted Function

The increasing emergence of antimicrobial resistance has become a global issue. Therefore, many researchers have attempted to develop alternative antibiotics. One promising alternative is bacteriophage. In this study, we focused on a jumbo-phage infecting Salmonella isolated from exotic pet markets. Using a Salmonella strain isolated from reptiles as a host, we isolated and characterized the novel jumbo-bacteriophage pSal-SNUABM-04. This phage was investigated in terms of its morphology, host infectivity, growth and lysis kinetics, and genome. The phage was classified as Myoviridae based on its morphological traits and showed a comparatively wide host range. The lysis efficacy test showed that the phage can inhibit bacterial growth in the planktonic state. Genetic analysis revealed that the phage possesses a 239,626-base pair genome with 280 putative open reading frames, 76 of which have a predicted function and 195 of which have none. By genome comparison with other jumbo phages, the phage was designated as a novel member of Machinavirus composed of Erwnina phages.

Characterization of the novel HLA‐DQA1 *05:19 allele by next‐generation sequencing

HLA ◽  
2021 ◽  
Author(s):  
Steve Genebrier ◽  
Paul Rouzaire ◽  
Emeric Texeraud ◽  
Gerald Bertrand ◽  
Virginie Renac
Keyword(s):  
Next Generation Sequencing ◽  
The Novel ◽  
Next Generation ◽  
Hla Dqa1 ◽  
Generation Sequencing

Characterization of the novel HLA‐C *05:01:58 allele by sequencing‐based typing

HLA ◽  
2021 ◽  
Author(s):  
Lucie Blandin ◽  
Gwendaline Guidicelli ◽  
Laura Blouin ◽  
Richard Lemal ◽  
Paul Rouzaire
Keyword(s):  
The Novel

Characterization of the novel HLA‐DPB1 *1139:01 allele by sequencing‐based typing

HLA ◽  
2021 ◽  
Author(s):  
Lucie Blandin ◽  
Laura Blouin ◽  
Marine Cargou ◽  
Richard Lemal ◽  
Paul Rouzaire
Keyword(s):  
The Novel

Characterization of the novel HLA‐C *01:214 allele by sequencing‐based typing

HLA ◽  
2021 ◽  
Author(s):  
Marine Cargou ◽  
Vincent Elsermans ◽  
Isabelle Top ◽  
Gwendaline Guidicelli ◽  
Jonathan Visentin
Keyword(s):  
The Novel

Characterization of the novel HLA‐A *01:367 allele by sequencing‐based typing

HLA ◽  
2021 ◽  
Author(s):  
Marine Cargou ◽  
Vincent Elsermans ◽  
Isabelle Top ◽  
Laura Blouin ◽  
Jonathan Visentin
Keyword(s):  
The Novel
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