The two-dimensional Keller–Segel system with singular sensitivity and signal absorption: Global large-data solutions and their relaxation properties

2016 ◽  
Vol 26 (05) ◽  
pp. 987-1024 ◽  
Author(s):  
Michael Winkler

We consider the chemotaxis system [Formula: see text] as originally introduced in 1971 by Keller and Segel in the second of their seminal works. This system constitutes a prototypical model for taxis-driven pattern formation and front propagation in various biological contexts such as tumor angiogenesis, but in the higher-dimensional context any global existence theory for large-data solutions is yet lacking. In this work it is shown that in bounded planar domains [Formula: see text] with smooth boundary, for all reasonably regular initial data [Formula: see text] and [Formula: see text], the corresponding Neumann initial-boundary value problem possesses a global generalized solution. Thus particularly addressing arbitrarily large initial data, this goes beyond previously gained results asserting global existence of solutions only in spatial one-dimensional problems, or under certain smallness conditions on the initial data. The derivation of this result is based on a priori estimates for the quantities [Formula: see text] and [Formula: see text] in spatio-temporal [Formula: see text] spaces, where further boundedness and compactness properties are derived from the former by relying on the planar spatial setting in using an associated Moser–Trudinger inequality. Furthermore, some further boundedness and relaxation properties are derived, inter alia indicating that for any such solution we have [Formula: see text] in [Formula: see text] as [Formula: see text] for all finite [Formula: see text], and that in an appropriate generalized sense the quantities [Formula: see text] and [Formula: see text] eventually enter bounded sets in [Formula: see text] and [Formula: see text], respectively, with diameters only determined by the total population size [Formula: see text]. Finally, some numerical experiments illustrate the analytically obtained results.

2014 ◽  
Vol 638-640 ◽  
pp. 1700-1704
Author(s):  
Yue Hu

In this paper, we consider the existence of global solution to the initial-boundary value problem for some hyperbolic equation with P-Laplace operator and a nonlinear dissipative term using the compactness criteria and the monotone mapping’s method.


2008 ◽  
Vol 10 (06) ◽  
pp. 1151-1181
Author(s):  
ELENA I. KAIKINA

We study the initial-boundary value problem for the fractional Landau–Ginzburg equations on a segment. The aim of this paper is to prove the global existence of solutions to the inital-boundary value problem and to find the main term of the asymptotic representation of solutions.


2014 ◽  
Vol 2014 ◽  
pp. 1-12
Author(s):  
Said Mesloub

This paper is devoted to the study of the well-posedness of an initial boundary value problem for an odd higher order nonlinear pseudohyperbolic integrodifferential partial differential equation. We associate to the equationnnonlocal conditions andn+1classical conditions. Upon some a priori estimates and density arguments, we first establish the existence and uniqueness of the strongly generalized solution in a class of a certain type of Sobolev spaces for the associated linear mixed problem. On the basis of the obtained results for the linear problem, we apply an iterative process in order to establish the well-posedness of the nonlinear problem.


Author(s):  
Elena I. Kaikina

We are interested in the global existence and large-time behavior of solutions to the initial-boundary value problem for critical convective-type dissipative equationsut+ℕ(u,ux)+(an∂xn+am∂xm)u=0,(x,t)∈ℝ+×ℝ+,u(x,0)=u0(x),x∈ℝ+,∂xj−1u(0,t)=0forj=1,…,m/2, where the constantsan,am∈ℝ,n,mare integers, the nonlinear termℕ(u,ux)depends on the unknown functionuand its derivativeuxand satisfies the estimate|ℕ(u,v)|≤C|u|ρ|v|σwithσ≥0,ρ≥1, such that((n+2)/2n)(σ+ρ−1)=1,ρ≥1,σ∈[0,m). Also we suppose that∫ℝ+xn/2ℕdx=0. The aim of this paper is to prove the global existence of solutions to the inital-boundary value problem above-mentioned. We find the main term of the asymptotic representation of solutions in critical case. Also we give some general approach to obtain global existence of solution of initial-boundary value problem in critical convective case and elaborate general sufficient conditions to obtain asymptotic expansion of solution.


2012 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Meng Liu ◽  
Yuxiang Li

<p style='text-indent:20px;'>In this paper, we consider the following haptotaxis model describing cancer cells invasion and metastatic spread</p><p style='text-indent:20px;'><disp-formula> <label/> <tex-math id="FE1a"> \begin{document}$\begin{array}{*{20}{c}}{\left\{ {\begin{array}{*{20}{l}}{{u_t} = \Delta u - \chi \nabla \cdot (u\nabla w),}&amp;{x \in \Omega ,\;t &gt; 0,}\\{{v_t} = {d_v}\Delta v - \xi \nabla \cdot (v\nabla w),}&amp;{x \in \Omega ,\;t &gt; 0,}\\{{m_t} = {d_m}\Delta m + u - m,}&amp;{x \in \Omega ,\;t &gt; 0,}\\{{w_t} = - \left( {{\gamma _1}u + m} \right)w,}&amp;{x \in \Omega ,\;t &gt; 0,}\end{array}} \right.}&amp;{(0.1)}\end{array}$ \end{document} </tex-math></disp-formula></p><p style='text-indent:20px;'>where <inline-formula><tex-math id="M1">\begin{document}$ \Omega\subset \mathbb{R}^3 $\end{document}</tex-math></inline-formula> is a bounded domain with smooth boundary and the parameters <inline-formula><tex-math id="M2">\begin{document}$ \chi, \xi, d_{v}, d_{m},\gamma_{1}&gt;0 $\end{document}</tex-math></inline-formula>. Under homogeneous boundary conditions of Neumann type for <inline-formula><tex-math id="M3">\begin{document}$ u $\end{document}</tex-math></inline-formula>, <inline-formula><tex-math id="M4">\begin{document}$ v $\end{document}</tex-math></inline-formula>, <inline-formula><tex-math id="M5">\begin{document}$ m $\end{document}</tex-math></inline-formula> and <inline-formula><tex-math id="M6">\begin{document}$ w $\end{document}</tex-math></inline-formula>, it is proved that, for suitable smooth initial data <inline-formula><tex-math id="M7">\begin{document}$ (u_0, v_0, m_0, w_0) $\end{document}</tex-math></inline-formula>, the corresponding Neumann initial-boundary value problem possesses a global generalized solution.</p>


2016 ◽  
Vol 13 (01) ◽  
pp. 147-179
Author(s):  
Fuzhou Wu

We consider classical solutions to the initial boundary value problem for the non-isentropic compressible Euler equations with damping in several space dimensions. We establish a global existence theory for classical solutions to this system when the initial data are sufficiently small. We prove that the pressure and the velocity converge exponentially toward some constants, while the entropy and the density in general do not approach constants. Finally, we prove that, as the time goes to infinity, the pressure and the velocity components of the non-isentropic Euler equations with damping converge exponentially toward those of an associated nonlinear diffusion system, and the global existence of classical solutions to these nonlinear diffusion equations is also established.


2014 ◽  
Vol 95 (109) ◽  
pp. 49-62 ◽  
Author(s):  
Bosko Jovanovic ◽  
Zorica Milovanovic

We study the convergence of a finite difference scheme that approximates the third initial-boundary-value problem for a parabolic equation with variable coefficients on a unit square. We assume that the generalized solution of the problem belongs to the Sobolev space W s,s/2 2, s?3. An almost second-order convergence rate estimate (with additional logarithmic factor) in the discrete W 1,1/2 2 norm is obtained. The result is based on some nonstandard a priori estimates involving fractional order discrete Sobolev norms.


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