Abstract
Since 2019, the antigens from Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) are keeping in evolution from initial D614, to G614, to Delta, and to Omicron. Seven of the peptides from SARS-CoV-2 are analyzed. The finding is that, the rule or route for the evolution of their antigens are exactly from “rough” status to “precise”. In this paper, we would like to show the initial data how the antigens from initial D614, conducted evolution to G614, to Delta of SARS-CoV-2. This finding can help the development of reagents for detecting the both “rough” and “precise” antigens, or even help for the development of the vaccines against SARS-CoV-2. And finally, to help the control of epidemic covid-19. According to such rule or route, the “common precise” antigens of the SARS-CoV-2 can be designed in silicon, developed in laboratory, and confirmed in animals. The way should be very tough and long.