A manganese porphyrin-based sensor for flow-injection potentiometric determination of thiocyanate

Metalloporphyrin-based ion-selective electrodes for flow-injection potentiometric determination of thiocyanate are described. The detection system is based on a coated glassy carbon electrode membrane sensor incorporating 5,10,15,20-tetraphenyl-21H,23H-porphine manganese(III) chloride as the active ingredient. The influences of the membrane composition, pH, and the effects of flow-injection parameters on the response of the system were investigated. At the optimized flow-injection potentiometric conditions, the sensor exhibited a Nernstian slope of -58.0 mV per decade of thiocyanate activity over the range 4.2 × 10-7–7.6 × 10-2M , where 50 μL of each sample solution was injected into the carrier solution. The detection limit of thiocyanate in the FIP mode was 4.2 × 10-7M . The selectivity of the flow-injection potentiometric system with respect to several common inorganic and organic anions was superior to that of the batch mode using the same sensor and similar operating conditions. The sensor was applied to the determination of thiocyanate in urine samples.