MCVM: MONTE CARLO MODELING OF PHOTON MIGRATION IN VOXELIZED MEDIA

2010 ◽  
Vol 03 (02) ◽  
pp. 91-102 ◽  
Author(s):  
TING LI ◽  
HUI GONG ◽  
QINGMING LUO

The Monte Carlo code MCML (Monte Carlo modeling of light transport in multi-layered tissue) has been the gold standard for simulations of light transport in multi-layer tissue, but it is ineffective in the presence of three-dimensional (3D) heterogeneity. New techniques have been attempted to resolve this problem, such as MCLS, which is derived from MCML, and tMCimg, which draws upon image datasets. Nevertheless, these approaches are insufficient because of their low precision or simplistic modeling. We report on the development of a novel model for photon migration in voxelized media (MCVM) with 3D heterogeneity. Voxel crossing detection and refractive-index-unmatched boundaries were considered to improve the precision and eliminate dependence on refractive-index-matched tissue. Using a semi-infinite homogeneous medium, steady-state and time-resolved simulations of MCVM agreed well with MCML, with high precision (~100%) for the total diffuse reflectance and total fractional absorption compared to those of tMCimg (< 70%). Based on a refractive-index-matched heterogeneous skin model, the results of MCVM were found to coincide with those of MCLS. Finally, MCVM was applied to a two-layered sphere with multi-inclusions, which is an example of a 3D heterogeneous media with refractive-index-unmatched boundaries. MCVM provided a reliable model for simulation of photon migration in voxelized 3D heterogeneous media, and it was developed to be a flexible and simple software tool that delivers high-precision results.

2010 ◽  
Author(s):  
Ching-Cheng Chuang ◽  
Chung-Ming Chen ◽  
Chia-Yen Lee ◽  
Jui-che Tsai ◽  
Chih-Wei Lu ◽  
...  

2020 ◽  
Vol 65 (1) ◽  
pp. 54-58
Author(s):  
T. Medjadj ◽  
A. Ksenofontov ◽  
A. Dalechina

Purpose: To develop an effective method of Monte Carlo simulation of the GammaKnife Perfexion system by rotating particles in the phase space file (PSF). This method does not require simulating of all 192 sources that are distributed in the conical form of the Perfexion collimator. The simulation was performed only for 5 out of 192 sources for each collimator size. Material and methods: Monte Carlo simulation of dose distribution for previous models of GammaKnife system requires phase space file for only one source, since this phase space is identical for all the 201 sources. The Perfexion model is more complex due to the non-coaxial positions of the sources and the complexity of the collimator system itself. In this work, we present an effective method to simulate the Perfexion model using a phase space file. Penelope Monte Carlo code was used to perform this simulation. In this method, the PSF was obtained for one source in each ring, resulting in five files for each collimator size. PSF for other sources were created by azimuthal redistribution of particles, in the obtained PSF, by rotation around the Z-axis. The phase space files of the same ring were then stored together in a single file. Results: The paper presented MC simulation using the azimuthal redistribution of particles in the phase space file by rotation around the Z-axis. The simulation has been validated comparing the dose profiles and output factors with the data of the algorithm TMR10 planning system Leksell Gamma Plan (LGP) in a homogeneous environment. The acceptance criterion between TMR10 and Monte Carlo calculations for the profiles was based on the gamma index (GI). Index values more than one were not detected in all cases, which indicates a good agreement of results. The differences between the output factors obtained in this work and the TMR10 data for collimators 8 mm and 4 mm are 0.74 and 0.73 %, respectively. Conclusion: In this work successfully implemented an effective method of simulating the Leksell Gamma knife Perfexion system. The presented method does not require modeling for all 192 sources distributed in the conical form of the Perfexion collimator. The simulation was performed for only five sources for each collimator and their files PSF were obtained. These files were used to create the PSF files for other sources by azimuthal redistribution of particles, in these files, by rotation around the Z-axis providing correct calculations of dose distributions in a homogeneous medium for 16, 8 and 4 mm collimators.


2007 ◽  
Vol 15 (21) ◽  
pp. 14086 ◽  
Author(s):  
Eduardo Margallo-Balbás ◽  
Patrick J. French

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