Coastal reclamation in Guangdong Province is highly concentrated and is growing rapidly. However, intensive reclamation use has resulted in serious influence on the coastal ecosystem, directly and indirectly. The current conditions and spatial distribution of reclamations must be detected for coastal preservation and management using efficient technology. This study aims to find a suitable method and data to map reclamations accurately at a large scale. Pixel-based and object-oriented classification methods were applied in extracting the three typical types of coastal reclamation, namely, ports, aquaculture ponds, and salt pans, in Guangdong Province from Landsat 8 and Sentinel 2 images. The algorithms of a support vector machine, random forest, decision tree, and rule-based algorithm were performed. Classification results were compared with statistical measures to assess the performance of different algorithms. The results indicated that all of the algorithms could obtain classification results with high accuracy, whereas the object-oriented algorithm showed less efficiency than other algorithms in classifying ports with complicated features. High-resolution data were not always superior to lower-resolution data in the reclamation classification. Generally speaking, applying the rule-based object-oriented algorithm in Sentinel 2A MSI images is relatively efficient at detecting the reclamation use in coastal Guangdong considering its actual situation. The mapping of reclamations in the whole of coastal Guangdong shows that they present obvious agglomeration characteristics in the space. The aquaculture ponds are mainly distributed in the coastal zones of western Guangdong and eastern Guangdong, with the largest area of 77,963 ha. The other types of ports are mainly distributed in the coastal zones of the Pearl River Delta, with an area of 8146 ha, while salt pans are mainly distributed in the coastal zones of Jiangmen, Zhuhai, and Zhongshan, with a total area of 4072 ha. The results can provide key supporting data for decision making in coastal management and preservation.