scholarly journals Brain effective connectivity modeling for alzheimer's disease by sparse gaussian bayesian network

Author(s):  
Shuai Huang ◽  
Jing Li ◽  
Jieping Ye ◽  
Adam Fleisher ◽  
Kewei Chen ◽  
...  
2006 ◽  
Vol 14 (7S_Part_1) ◽  
pp. P35-P36
Author(s):  
Cole John Cook ◽  
Gyujoon Hwang ◽  
Veena A. Nair ◽  
Andrew L. Alexander ◽  
Piero G. Antuono ◽  
...  

2014 ◽  
Vol 578 ◽  
pp. 171-175 ◽  
Author(s):  
Yufang Zhong ◽  
Liyu Huang ◽  
Suping Cai ◽  
Yun Zhang ◽  
Karen M. von Deneen ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-13 ◽  
Author(s):  
Ziming Yin ◽  
Yinhong Zhao ◽  
Xudong Lu ◽  
Huilong Duan

Neuropsychological testing is an effective means for the screening of Alzheimer’s disease. Multiple neuropsychological rating scales should be used together to get subjects’ comprehensive cognitive state due to the limitation of a single scale, but it is difficult to operate in primary clinical settings because of the inadequacy of time and qualified clinicians. Aiming at identifying AD’s stages more accurately and conveniently in screening, we proposed a computer-aided diagnosis approach based on critical items extracted from multiple neuropsychological scales. The proposed hybrid intelligent approach combines the strengths of rough sets, genetic algorithm, and Bayesian network. There are two stages: one is attributes reduction technique based on rough sets and genetic algorithm, which can find out the most discriminative items for AD diagnosis in scales; the other is uncertain reasoning technique based on Bayesian network, which can forecast the probability of suffering from AD. The experimental data set consists of 500 cases collected by a top hospital in China and each case is determined by the expert panel. The results showed that the proposed approach could not only reduce items drastically with the same classification precision, but also perform better on identifying different stages of AD comparing with other existing scales.


2010 ◽  
Vol 53 (10) ◽  
pp. 733-748 ◽  
Author(s):  
Xingfeng Li ◽  
Damien Coyle ◽  
Liam Maguire ◽  
David R Watson ◽  
Thomas M McGinnity

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