Penicillin-Binding Proteins and the Mechanism of Action of Beta-Lactam Antibiotics1

Annual Review of Biochemistry ◽

10.1146/annurev.bi.52.070183.004141 ◽

1983 ◽

Vol 52 (1) ◽

pp. 825-869 ◽

Author(s):

D J Waxman ◽

J L Strominger

Keyword(s):

Mechanism Of Action ◽

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins

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beta-Lactam resistance in Streptococcus pneumoniae: penicillin-binding proteins and non-penicillin-binding proteins

Molecular Microbiology ◽

10.1046/j.1365-2958.1999.01521.x ◽

1999 ◽

Vol 33 (4) ◽

pp. 673-678 ◽

Author(s):

Regine Hakenbeck ◽

Thorsten Grebe ◽

Dorothea Zahner ◽

Jeffry B. Stock

Keyword(s):

Streptococcus Pneumoniae ◽

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins

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Modification of penicillin-binding proteins as mechanisms of beta-lactam resistance.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.30.1.1 ◽

1986 ◽

Vol 30 (1) ◽

pp. 1-5 ◽

Author(s):

F Malouin ◽

L E Bryan

Keyword(s):

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins

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Interaction of beta-Lactam Antibiotics with Penicillin-Binding Proteins from Bacillus megaterium

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1982.tb06761.x ◽

1982 ◽

Vol 126 (1) ◽

pp. 161-166 ◽

Author(s):

Alfredo RODRIGUEZ-TEBAR ◽

Fernando ROJO ◽

David VAZQUEZ

Keyword(s):

Bacillus Megaterium ◽

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Beta Lactam Antibiotics

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Enzymatic studies on the mechanism of action of cefoxitin. Correlation between the affinities of cefoxitin to penicillin-binding proteins and its rates of inhibition of the respective penicillin-sensitive reactions in E. coli.

The Journal of Antibiotics ◽

10.7164/antibiotics.31.1292 ◽

1978 ◽

Vol 31 (12) ◽

pp. 1292-1295 ◽

Author(s):

MICHIO MATSUHASHI ◽

SHIGEO TAMAKI

Keyword(s):

Mechanism Of Action ◽

Binding Proteins ◽

Penicillin Binding Proteins ◽

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Labelling and cross-linking of Escherichia coli penicillin-binding proteins with bis-beta-lactam antibiotics

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1984.tb08006.x ◽

1984 ◽

Vol 139 (2) ◽

pp. 287-293 ◽

Author(s):

Alfredo RODRIGUEZ-TEBAR ◽

Vicente ARAN ◽

David VAZQUEZ

Keyword(s):

Escherichia Coli ◽

Binding Proteins ◽

Cross Linking ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Beta Lactam Antibiotics

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Competition of beta-lactam antibiotics for the penicillin-binding proteins of Pseudomonas aeruginosa, Enterobacter cloacae, Klebsiella aerogenes, Proteus rettgeri, and Escherichia coli: comparison with antibacterial activity and effects upon bacterial morphology.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.16.3.325 ◽

1979 ◽

Vol 16 (3) ◽

pp. 325-328 ◽

Author(s):

N A Curtis ◽

D Orr ◽

G W Ross ◽

M G Boulton

Keyword(s):

Escherichia Coli ◽

Pseudomonas Aeruginosa ◽

Antibacterial Activity ◽

Binding Proteins ◽

Enterobacter Cloacae ◽

Klebsiella Aerogenes ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Beta Lactam Antibiotics ◽

Bacterial Morphology

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Penicillin-binding proteins in a Staphylococcus aureus strain resistant to specific beta-lactam antibiotics.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.22.1.172 ◽

1982 ◽

Vol 22 (1) ◽

pp. 172-175 ◽

Author(s):

N H Georgopapadakou ◽

S A Smith ◽

D P Bonner

Keyword(s):

Staphylococcus Aureus ◽

Binding Proteins ◽

Aureus Strain ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Beta Lactam Antibiotics

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Penicillin-binding proteins of penicillin-susceptible and -resistant pneumococci: immunological relatedness of altered proteins and changes in peptides carrying the beta-lactam binding site.

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.30.4.553 ◽

1986 ◽

Vol 30 (4) ◽

pp. 553-558 ◽

Author(s):

R Hakenbeck ◽

H Ellerbrok ◽

T Briese ◽

S Handwerger ◽

A Tomasz

Keyword(s):

Binding Site ◽

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Altered Proteins

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Involvement of penicillin-binding protein 2 with other penicillin-binding proteins in lysis of Escherichia coli by some beta-lactam antibiotics alone and in synergistic lytic effect of amdinocillin (mecillinam).

Antimicrobial Agents and Chemotherapy ◽

10.1128/aac.30.6.906 ◽

1986 ◽

Vol 30 (6) ◽

pp. 906-912 ◽

Author(s):

L Gutmann ◽

S Vincent ◽

D Billot-Klein ◽

J F Acar ◽

E Mrena ◽

...

Keyword(s):

Escherichia Coli ◽

Binding Proteins ◽

Binding Protein ◽

Penicillin Binding Protein ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Lytic Effect ◽

Beta Lactam Antibiotics

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Interaction of Beta-Lactam Antibiotics with the Penicillin-Binding Proteins of Penicillin-Resistant Streptococcus pneumoniae

Chemotherapy ◽

10.1159/000239338 ◽

1995 ◽

Vol 41 (3) ◽

pp. 159-164 ◽

Author(s):

Fumiaki Ikeda ◽

Yoshiko Yokota ◽

Akiko Ikemoto ◽

Noriko Teratani ◽

Kyoichi Shimomura ◽

...

Keyword(s):

Streptococcus Pneumoniae ◽

Binding Proteins ◽

Beta Lactam ◽

Penicillin Binding Proteins ◽

Beta Lactam Antibiotics

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