A Novel CMOS Image Sensor Using Time-Domain Single-Photon Counting

2016 ◽  
Vol 2016 ◽  
pp. 1-23 ◽  
Author(s):  
Yves Bérubé-Lauzière ◽  
Matteo Crotti ◽  
Simon Boucher ◽  
Seyedrohollah Ettehadi ◽  
Julien Pichette ◽  
...  

This paper discusses instrumentation based on multiview parallel high temporal resolution (<50 ps) time-domain (TD) measurements for diffuse optical tomography (DOT) and a prospective view on the steps to undertake as regards such instrumentation to make TD-DOT a viable technology for small animal molecular imaging. TD measurements provide information-richest data, and we briefly review the interaction of light with biological tissues to provide an understanding of this. This data richness is yet to be exploited to its full potential to increase the spatial resolution of DOT imaging and to allow probing, via the fluorescence lifetime, tissue biochemical parameters, and processes that are otherwise not accessible in fluorescence DOT. TD data acquisition time is, however, the main factor that currently compromises the viability of TD-DOT. Current high temporal resolution TD-DOT scanners simply do not integrate sufficient detection channels. Based on our past experience in developing TD-DOT instrumentation, we review and discuss promising technologies to overcome this difficulty. These are single photon avalanche diode (SPAD) detectors and fully parallel highly integrated electronics for time-correlated single photon counting (TCSPC). We present experimental results obtained with such technologies demonstrating the feasibility of next-generation multiview TD-DOT therewith.


2017 ◽  
Vol 66 (10) ◽  
pp. 2505-2515 ◽  
Author(s):  
Jonathan Bouchard ◽  
Arnaud Samson ◽  
William Lemaire ◽  
Caroline Paulin ◽  
Jean-Francois Pratte ◽  
...  

Author(s):  
Neale A.W. Dutton ◽  
Luca Parmesan ◽  
Andrew J. Holmes ◽  
Lindsay A. Grant ◽  
Robert K. Henderson

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 4016 ◽  
Author(s):  
Chao Zhang ◽  
Scott Lindner ◽  
Ivan Antolovic ◽  
Martin Wolf ◽  
Edoardo Charbon

Per-pixel time-to-digital converter (TDC) architectures have been exploited by single-photon avalanche diode (SPAD) sensors to achieve high photon throughput, but at the expense of fill factor, pixel pitch and readout efficiency. In contrast, TDC sharing architecture usually features high fill factor at small pixel pitch and energy efficient event-driven readout. While the photon throughput is not necessarily lower than that of per-pixel TDC architectures, since the throughput is not only decided by the TDC number but also the readout bandwidth. In this paper, a SPAD sensor with 32 × 32 pixels fabricated with a 180 nm CMOS image sensor technology is presented, where dynamically reallocating TDCs were implemented to achieve the same photon throughput as that of per-pixel TDCs. Each 4 TDCs are shared by 32 pixels via a collision detection bus, which enables a fill factor of 28% with a pixel pitch of 28.5 μm. The TDCs were characterized, obtaining the peak-to-peak differential and integral non-linearity of −0.07/+0.08 LSB and −0.38/+0.75 LSB, respectively. The sensor was demonstrated in a scanning light-detection-and-ranging (LiDAR) system equipped with an ultra-low power laser, achieving depth imaging up to 10 m at 6 frames/s with a resolution of 64 × 64 with 50 lux background light.


2016 ◽  
Vol 63 (1) ◽  
pp. 189-196 ◽  
Author(s):  
Neale A. W. Dutton ◽  
Istvan Gyongy ◽  
Luca Parmesan ◽  
Salvatore Gnecchi ◽  
Neil Calder ◽  
...  

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