beta-Adrenergic stimulation of respiratory ciliary activity

1980 ◽  
Vol 48 (5) ◽  
pp. 868-871 ◽  
Author(s):  
P. Verdugo ◽  
N. T. Johnson ◽  
P. Y. Tam

We investigated the effect of isoproterenol on ciliary activity using a mucus-free preparation of cultured ciliated cells of the rabbit trachea. The frequency of ciliary beating was monitored by dynamic laser-scattering spectroscopy. The results demonstrated that isoproterenol directly stimulates the activity of ciliated cells of the respiratory epithelium and that this effect is beta-adrenergic specific inasmuch as the observed stimulation can be blocked by propranolol.

Circulation ◽  
1984 ◽  
Vol 69 (5) ◽  
pp. 955-962 ◽  
Author(s):  
G S Roubin ◽  
C Y Choong ◽  
S Devenish-Meares ◽  
N N Sadick ◽  
P J Fletcher ◽  
...  

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