Cell Adhesion Molecules: Key Players in Memory Consolidation?

Physiology ◽  
2003 ◽  
Vol 18 (4) ◽  
pp. 147-150 ◽  
Author(s):  
Hans Welzl ◽  
Oliver Stork
Keyword(s):  
Cell Adhesion ◽  
Neural Plasticity ◽  
Memory Consolidation ◽  
Cell Adhesion Molecules ◽  
Cell Adhesion Molecule ◽  
Neural Cell Adhesion Molecule ◽  
Long Term Memory ◽  
Learning Tasks ◽  
Neural Cell Adhesion

Experimental evidence implies that L1 and neural cell adhesion molecule (NCAM) are involved in long-term memory formation. Changes in their expression and glycosylation appear to modify the synaptic strength underlying memory consolidation. Interference with L1 and NCAM function in a variety of learning tasks in different species severely attenuates memory consolidation, indicating their involvement in an evolutionary conserved mechanism of neural plasticity.

Neural cell adhesion molecules, CaM kinase II and long-term memory in the chick

Neuroreport ◽  
2000 ◽  
Vol 11 (14) ◽  
pp. 3139-3143 ◽  
Author(s):  
Revaz O. Solomonia ◽  
Tamar Kiguradze ◽  
Brian J. McCabe ◽  
Gabriel Horn
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Long Term Memory ◽  
Cam Kinase Ii ◽  
Cam Kinase ◽  
Term Memory ◽  
Neural Cell Adhesion Molecules ◽  
Neural Cell Adhesion
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