Apoptotic Cell Death Under Hypoxia

Physiology ◽  
2014 ◽  
Vol 29 (3) ◽  
pp. 168-176 ◽  
Author(s):  
Ataman Sendoel ◽  
Michael O. Hengartner

Eukaryotic life depends largely on molecular oxygen. During evolution, ingenious mechanisms have evolved that allow organisms to adapt when oxygen levels decrease. Many of these adaptional responses to low oxygen are orchestrated by the heterodimeric transcription factor hypoxia-inducible factor (HIF). Here, we review the link between HIF and apoptosis.

FEBS Letters ◽  
1999 ◽  
Vol 457 (3) ◽  
pp. 478-482 ◽  
Author(s):  
Elisabet Chalaux ◽  
Teresa López-Rovira ◽  
Jose Luis Rosa ◽  
Gabriel Pons ◽  
Linda M. Boxer ◽  
...  

1997 ◽  
Vol 11 (15) ◽  
pp. 1938-1948 ◽  
Author(s):  
M. Moser ◽  
A. Pscherer ◽  
C. Roth ◽  
J. Becker ◽  
G. Mucher ◽  
...  

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