scholarly journals Side of Onset in Parkinson’s Disease and Alterations in Religiosity: Novel Behavioral Phenotypes

2011 ◽  
Vol 24 (2) ◽  
pp. 133-141 ◽  
Author(s):  
Paul M. Butler ◽  
Patrick McNamara ◽  
Raymon Durso
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Religious Belief ◽  
Complex Disease ◽  
Patient Centered ◽  
Religious Ritual ◽  
Treatment Plans ◽  
The Aesthetic ◽  
Prime Condition ◽  
Neurologically Intact

Behavioral neurologists have long been interested in changes in religiosity following circumscribed brain lesions. Advances in neuroimaging and cognitive experimental techniques have been added to these classical lesion-correlational approaches in attempt to understand changes in religiosity due to brain damage. In this paper we assess processing dynamics of religious cognition in patients with Parkinson’s disease (PD). We administered a four-condition story-based priming procedure, and then covertly probed for changes in religious belief. Story-based priming emphasized mortality salience, religious ritual, and beauty in nature (Aesthetic). In neurologically intact controls, religious belief-scores significantly increased following the Aesthetic prime condition. When comparing effects of right (RO) versus left onset (LO) in PD patients, a double-dissociation in religious belief-scores emerged based on prime condition. RO patients exhibited a significant increase in belief following the Aesthetic prime condition and LO patients significantly increased belief in the religious ritual prime condition. Results covaried with executive function measures. This suggests lateral cerebral specialization for ritual-based (left frontal) versus aesthetic-based (right frontal) religious cognition. Patient-centered individualized treatment plans should take religiosity into consideration as a complex disease-associated phenomenon connected to other clinical variables and health outcomes.

Delivering patient-centered care in Parkinson's disease: Challenges and consensus from an international panel

2020 ◽  
Vol 72 ◽  
pp. 82-87 ◽  
Author(s):  
Roongroj Bhidayasiri ◽  
Pattamon Panyakaew ◽  
Claudia Trenkwalder ◽  
Beomseok Jeon ◽  
Nobutaka Hattori ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Patient Centered Care ◽  
Patient Centered ◽  
International Panel ◽  
Centered Care

scholarly journals Automated Stage Discrimination of Parkinson’s Disease

2020 ◽  
Vol 1 (2) ◽  
pp. 55-63
Author(s):  
Vered Aharonson ◽  
Nabeel Seedat ◽  
Simon Israeli-Korn ◽  
Sharon Hassin-Baer ◽  
Michiel Postema ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Rating Scale ◽  
Motor Fluctuation ◽  
Step Length ◽  
Disease Stage ◽  
Physical Parameters ◽  
Timed Up And Go ◽  
Step Velocity ◽  
Treatment Plans

Abstract Background: Treatment plans for Parkinson’s disease (PD) are based on a disease stage scale, which is generally determined using a manual, observational procedure. Automated, sensor-based discrimination saves labor and costs in clinical settings and may offer augmented stage determination accuracy. Previous automated devices were either cumbersome or costly and were not suitable for individuals who cannot walk without support.Methods: Since 2017, a device has been available that successfully detects PD and operates for people who cannot walk without support. In the present study, the suitability of this device for automated discrimination of PD stages was tested. The device consists of a walking frame fitted with sensors to simultaneously support walking and monitor patient gait. Sixty-five PD patients in Hoehn and Yahr (HY) stages 1 to 4 and 24 healthy controls were subjected to supported Timed Up and Go (TUG) tests, while using the walking frame. The walking trajectory, velocity, acceleration and force were recorded by the device throughout the tests. These physical parameters were converted into symptomatic spatiotemporal quantities that are conventionally used in PD gait assessment.Results: An analysis of variance (ANOVA) test extended by a confidence interval (CI) analysis indicated statistically significant separability between HY stages for the following spatiotemporal quantities: TUG time (p < 0.001), straight line walking time (p < 0.001), turning time (p < 0.001), and step count (p < 0.001). A negative correlation was obtained for mean step velocity (p < 0.001) and mean step length (p < 0.001). Moreover, correlations were established between these, as well as additional spatiotemporal quantities, and disease duration, L-dihydroxyphenylalanine-(L-DOPA) dose, motor fluctuation, dyskinesia and the mobile part of the Unified Parkinson Disease Rating Scale (UPDRS).Conclusions: We have proven that stage discrimination of PD can be automated, even to patients who cannot support themselves. A similar method might be successfully applied to other gait disorders.

scholarly journals Non-motor clinical manifestations of Parkinson’s disease and its relevance in early diagnosis

2021 ◽  
Author(s):  
Lucca Ferdinando Queiroz Fernandes ◽  
Raiana Carol de Medeiros Dantas ◽  
Maria Clara Medeiros Araújo ◽  
Lucas de Oliveira Araújo Andrade
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sleep Disorders ◽  
Complex Disease ◽  
Clinical Manifestations ◽  
Olfactory Dysfunction ◽  
Screening Tests ◽  
Motor Symptoms ◽  
Scientific Publications ◽  
Study Results

Introduction: Parkinson’s disease is a progressive neurodegenerative disease that affects millions of people worldwide. Although Parkinson’s disease has traditionally been described as a disorder of the motor system, it is now recognized as a complex disease with several clinical features that include neuropsychiatric and non-motor manifestations. Studies show that 97% of patients with Parkinson’s disease report non-motor symptoms, in addition to motor symptoms, and some non-motor characteristics may appear before classic motor signs. Objectives: To list the main non-motor clinical manifestations of Parkinson’s disease and analyze its importance in establishing an accurate and early clinical diagnosis. Methods: This is an integrative review, carried out based on the search of scientific publications indexed in the datebase MEDLINE via PubMed, Lilacs and SciELO. At the end of the searches, 66 publications met the eligibility criteria and were selected to compose the study. Results: Within the non-motor clinical manifestations, there may be present: cognitive dysfunction and dementia, psychosis and hallucinations, mood disorders, sleep disorders, fatigue, autonomic dysfunction, olfactory dysfunction, gastrointestinal dysfunction, pain, sensory disorders and dermatological manifestations. Of these, olfactory dysfunction, constipation, depression and sleep disorders stand out because they often precede the motor symptoms of Parkinson’s disease. Conclusion: In this perspective, it is up to the general practitioner and the neurologist or geriatrician to carry out, whenever possible, screening tests to identify early changes that may precede Parkinson’s disease, guaranteeing patients an early multiprofessional treatment and consequently a better prognosis in the course of the disease.

scholarly journals Aesthetics in motion: The beauty of action paintings as revealed by Parkinson’s disease

2020 ◽  
Author(s):  
Stacey Humphries ◽  
Jacqueline Rick ◽  
Daniel Weintraub ◽  
Anjan Chatterjee
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Motor System ◽  
Aesthetic Judgment ◽  
Aesthetic Appreciation ◽  
Visual Metaphor ◽  
Embodied Simulation ◽  
Aesthetic Experiences ◽  
Subjective Value ◽  
The Aesthetic

Visual art offers cognitive neuroscience an opportunity to study how subjective value is constructed from representations supported by multiple neural systems. A surprising finding in research on aesthetic judgment is that functional activation of motor areas of the brain often occurs in response to static, abstract stimuli, such as paintings. This motor activity has variously been hypothesised to reflect the embodied simulation of an artist’s painting movements or emotions, as well as possible preparatory approach-avoidance responses to liked and disliked artworks. However, whether this motor involvement functionally contributes to aesthetic appreciation has not been addressed. Here, we examined whether motor system dysfunction alters the aesthetic experiences of patients with Parkinson’s disease. 43 people with Parkinson’s disease and 40 controls made preference decisions and rated the motion content and their aesthetic appreciation of a set of high-motion action paintings (by Jackson Pollock) and a set of low-motion neoplastic paintings (by Piet Mondrian). People with Parkinson’s disease demonstrated stable and internally consistent preferences for abstract art, but their perception of movement in the paintings was significantly lower in both conditions than that of controls. In addition, people with Parkinson’s demonstrated enhanced preferences for high-motion art, and a fundamentally altered relationship between motion and aesthetic appreciation. Our results do not accord well with a straightforward embodied simulation account of aesthetic experiences, because artworks that did not include visual traces of the artist’s actions were still experienced as lower in motion by Parkinson’s patients. We suggest that the ability to form movement representations from static abstract images is more akin to a process of visual metaphor comprehension that is mediated through the motor system. Overall, we find support for hypotheses linking motion, motor responses and aesthetic appreciation, and provide clear evidence that altered neural functioning changes the way art is perceived and valued.

scholarly journals Incorporating the Principles of Self-Management into Treatment of Dysarthria Associated with Parkinson's Disease

2017 ◽  
Vol 38 (03) ◽  
pp. 210-219 ◽  
Author(s):  
Carolyn Baylor ◽  
Deanna Britton ◽  
Kathryn Yorkston
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Current Treatment ◽  
Patient Perspectives ◽  
Self Management ◽  
Patient Centered ◽  
Treatment Expectations ◽  
Before And After ◽  
Centered Care ◽  
Speech Loudness

AbstractAlthough understanding patient perspectives on treatment is a major component of patient-centered care, little is known about patient perspectives related to dysarthria treatment in Parkinson's disease (PD). This article attempts to explore the perspective of patients with dysarthria associated with PD by interviewing them before and after treatment. Treatment expectations and experiences are summarized along with a discussion of how patients are using the tools they learned once treatment was completed. Comments about treatment were generally positive and suggested increased awareness and improved speech loudness. However, areas for improvement were also identified including: (1) treatment was not addressing some communication problems that were of concern to patients; (2) therapy programs were not enjoyable; and (3) it was difficult to maintain gains after therapy ended. Principles of self-management are reviewed to address some of the shortcomings of current treatment approaches.

scholarly journals Beyond patient-centered care: person-centered care for Parkinson’s disease

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Stephen A Buetow ◽  
Pablo Martínez-Martín ◽  
Mark A Hirsch ◽  
Michael S Okun
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Patient Centered Care ◽  
Patient Centered ◽  
Person Centered Care ◽  
Centered Care

scholarly journals Telerehabilitation for Communication and Swallowing Disorders in Parkinson’s Disease

2021 ◽  
pp. 1-6
Author(s):  
Deborah Theodoros
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
New Technologies ◽  
Negative Impact ◽  
Swallowing Disorders ◽  
Future Research ◽  
Patient Centered ◽  
Language Pathology

Communication and swallowing disorders are highly prevalent in people with Parkinson’s disease (PD). The negative impact of these disorders on the quality of life of the person with PD and their families cannot be underestimated. Despite a demand for speech-language pathology services to support people with PD, many barriers to services exist. Telerehabilitation provides an alternate and complementary approach to in-person therapy that is patient-centered, enables timely assessment and intervention, and facilitates continuity of care throughout the course of the disease. This review explores the telerehabilitation applications designed for the management of the communication and swallowing disorders in PD, addresses the benefits and challenges of telerehabilitation, identifies future research directions, and highlights the potential of new technologies to enhance the management of communication and swallowing disorders and quality of life for people with PD.

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