Hemorrhagic Shock as a Sequela of Splenic Rupture in a Patient with Infectious Mononucleosis: Focus on the Potential Role of Salicylates

Despite the fact that the vast majority of splenic ruptures are traumatic, infectious mononucleosis has been incriminated as a major predisposing factor that affects the integrity of the spleen, thus causing atraumatic ruptures and life-threatening hemorrhages. Herein we present a case of a 23-year-old Caucasian male who underwent an emergency laparotomy for acute abdomen and hemorrhagic shock, caused by spontaneous splenic rupture secondary to infectious mononucleosis. The potential role of salicylates in the development of a hemorrhagic complication in a patient with infectious mononucleosis is discussed.

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Nonoperative Management of Spontaneous Splenic Rupture in Infectious Mononucleosis: The Role for Emerging Diagnostic and Treatment Modalities

The American Surgeon ◽

10.1177/000313480607200507 ◽

2006 ◽

Vol 72 (5) ◽

pp. 401-404 ◽

Cited By ~ 4

Author(s):

I. Brichkov ◽

L. Cummings ◽

R. Fazylov ◽

J.H. Horovitz

Keyword(s):

Infectious Mononucleosis ◽

Splenic Rupture ◽

Nonoperative Management ◽

Treatment Modalities ◽

Minor Trauma ◽

Spontaneous Splenic Rupture ◽

Traditional Management ◽

Teenagers And Young Adults ◽

Common Manifestation

Infectious mononucleosis (IM) is a self-limiting lymphoproliferative disorder affecting teenagers and young adults. Splenomegaly is a common manifestation of IM and results in a compromised organ that may rarely rupture spontaneously, with significant morbidity and mortality. The IM spleen should be protected from even minor trauma. Although traditional management of spontaneous splenic rupture in IM has been splenectomy, the role of nonoperative management is evolving. The advent of endovascular interventional modalities has augmented the physician's armamentarium in managing these patients nonoperatively. We report a case of spontaneous splenic rupture in a patient with IM managed conservatively with the aid of splenic angiography. The option of arteriography, with or without embolization, should be considered in the management of all patients with spontaneous splenic rupture in the setting of IM.

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Hemorrhagic Shock from Spontaneous Splenic Rupture Requiring Open Splenectomy in a Patient Taking Rivaroxaban

The American Surgeon ◽

10.1177/000313481608200208 ◽

2016 ◽

Vol 82 (2) ◽

pp. 54-55 ◽

Cited By ~ 3

Author(s):

Arpit Amin ◽

Aditya Safaya ◽

Faisal Ronny ◽

Humayun Islam ◽

Kalyani Bhuta ◽

...

Keyword(s):

Hemorrhagic Shock ◽

Splenic Rupture ◽

Spontaneous Splenic Rupture ◽

Open Splenectomy

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Case Report: Clostridium neonatale Bacteremia in a Preterm Neonate With Necrotizing Enterocolitis

Frontiers in Pediatrics ◽

10.3389/fped.2021.771467 ◽

2021 ◽

Vol 9 ◽

Author(s):

Nadim Cassir ◽

Isabelle Grandvuillemin ◽

Manon Boxberger ◽

Priscilla Jardot ◽

Farid Boubred ◽

...

Keyword(s):

Necrotizing Enterocolitis ◽

Potential Role ◽

Preterm Neonate ◽

Gastrointestinal Disorder ◽

Etiologic Agent ◽

Preterm Neonates ◽

Environmental Cleaning ◽

Life Threatening

Necrotizing enterocolitis is a life-threatening acquired gastrointestinal disorder among preterm neonates and is associated with a high mortality rate and long-term neurodevelopmental morbidity. No etiologic agent has been definitively established; nonetheless, the most implicated bacteria include members of the Clostridium genus. We reported here on a case of Clostridium neonatale bacteremia in a preterm neonate with necrotizing enterocolitis, providing more information regarding the potential role of this bacterium in pathogenesis of necrotizing enterocolitis. We emphasized the sporulating form of C. neonatale that confers resistance to disinfectants usually applied for the hospital environmental cleaning. Further works are needed to establish the causal relationship between the occurrence of NEC and the isolation of C. neonatale, with promising perspectives in terms of diagnostic and therapeutic management.

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Life-threatening spontaneous splenic rupture with systemic lupus erythematosus: case report and literature review

Clinical Rheumatology ◽

10.1007/s10067-011-1934-8 ◽

2012 ◽

Vol 31 (6) ◽

pp. 1019-1025 ◽

Cited By ~ 5

Author(s):

Jie Han ◽

Ning Li ◽

JiaYi Wang ◽

JieRu Zhou ◽

Jie Zhang

Keyword(s):

Systemic Lupus Erythematosus ◽

Case Report ◽

Literature Review ◽

Lupus Erythematosus ◽

Splenic Rupture ◽

Spontaneous Splenic Rupture ◽

Systemic Lupus ◽

Systemic Lupus Erythematosus Case ◽

Life Threatening

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Successful Nonoperative Management of Spontaneous Splenic Hematoma and Hemoperitoneum due to CMV Infection

Case Reports in Gastrointestinal Medicine ◽

10.1155/2012/328474 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Georgios Lianos ◽

Eleftheria Ignatiadou ◽

Christina Bali ◽

Haralampos Harissis ◽

Christos Katsios

Keyword(s):

Case Report ◽

Rare Case ◽

Splenic Rupture ◽

Nonoperative Management ◽

Spontaneous Splenic Rupture ◽

Cmv Infection ◽

Life Threatening ◽

Splenic Hematoma ◽

Immunocompetent Adults ◽

Operating Surgeon

Introduction. Spontaneous splenic hematoma or splenic rupture due to CMV infection in immunocompetent adults is rare and life-threatening.Case Report. Herein we report a rare case of spontaneous splenic hematoma and hemoperitoneum due to CMV infection in a 23-year-old Caucasian male in whom conservative management was successful.Conclusion. Spontaneous splenic hematoma and spontaneous splenic rupture are extremely rare conditions during primary CMV infection. Though rare, they must be always considered by the operating surgeon, because any misinterpretation may result in unfavorable outcomes.

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Spontaneous Splenic Rupture and Rituximab-Induced Acute Thrombocytopenia in a Patient with High-Risk Mantle Cell Lymphoma

Case Reports in Hematology ◽

10.1155/2019/2429098 ◽

2019 ◽

Vol 2019 ◽

pp. 1-4 ◽

Cited By ~ 1

Author(s):

Jared Williams ◽

Shingi Chiruka

Keyword(s):

High Risk ◽

Mantle Cell Lymphoma ◽

Rare Case ◽

Splenic Rupture ◽

Cell Lymphoma ◽

Case Reports ◽

Spontaneous Splenic Rupture ◽

Rare Type ◽

Mantle Cell ◽

Life Threatening

Mantle cell lymphoma is a relatively rare type of mature B-cell non-Hodgkin’s lymphoma with an incidence of approximately 8 cases per million persons per year. In patients with mantle cell lymphoma, there are rare case reports of the potentially life-threatening consequences of splenic rupture and rituximab-induced acute thrombocytopenia (RIAT) occurring separately, but there are no reports of these occurring in the same patient. Whilst rare, they are important to be aware of as early detection may prevent fatal outcomes.

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P0669 SPONTANEOUS SPLENIC RUPTURE SECONDARY TO INFECTIOUS MONONUCLEOSIS

European Journal of Internal Medicine ◽

10.1016/s0953-6205(09)60688-9 ◽

2009 ◽

Vol 20 ◽

pp. S219 ◽

Cited By ~ 1

Author(s):

Sunanda Mavinamane ◽

Rajendra Yadava ◽

Emad Abood

Keyword(s):

Infectious Mononucleosis ◽

Splenic Rupture ◽

Spontaneous Splenic Rupture

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The “Fountain of Death”: A Case Series on Tracheo-innominate Artery Fistula

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v20i2.727 ◽

2021 ◽

Vol 20 (2) ◽

Author(s):

Jason Lo ◽

Marina Mat Baki ◽

Yeoh Xing Yi ◽

Nik Hisyam Amirul ◽

Zahirrudin Zakaria

Keyword(s):

Potential Role ◽

Rare Complication ◽

Case Series ◽

Innominate Artery ◽

Survival Outcomes ◽

Permissive Hypotension ◽

Life Threatening ◽

History Of ◽

High Index Of Suspicion

Tracheo-innominate artery fistula (TIF) is a very rare complication related to tracheostomy and has been reported in 0.7% of patients, but certainly is one of the most life-threatening conditions. It is of paramount importance to maintain a high index of suspicion in evaluating patients with TIF and to anticipate occurrence of massive haemorrhage even during simple procedures related to tracheostomy such as tube change. We report 3 cases of TIF, each with a unique and unsuspecting history of the condition and review the emergency protocol in arresting the bleeding. We’ve also highlighted the potential role of permissive hypotension with sedation in improving survival outcomes of patients with TIF.

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