scholarly journals Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Ting-Kai Leung ◽  
Chin-Feng Chan ◽  
Ping-Shan Lai ◽  
Chih-Hui Yang ◽  
Chia-Yen Hsu ◽  
...  
Keyword(s):  
Ceramic Material ◽  
Biological Effects ◽  
Far Infrared ◽  
Melanoma Cells ◽  
Hsp70 Expression ◽  
Inhibitory Effects ◽  
Hsp 70 ◽  
Murine Melanoma ◽  
Irradiation Treatment ◽  
Murine Melanoma Cells

The biological effects of specific wavelengths, so-called “far-infrared radiation” produced from ceramic material (cFIR), on whole organisms are not yet well understood. In this study, we investigated the biological effects of cFIR on murine melanoma cells (B16-F10) at body temperature. cFIR irradiation treatment for 48 h resulted in an 11.8% decrease in the proliferation of melanoma cells relative to the control. Meanwhile, incubation of cells with cFIR for 48 h significantly resulted in 56.9% and 15.7% decreases in the intracellular heat shock protein (HSP)70 and intracellular nitric oxide (iNO) contents, respectively. Furthermore, cFIR treatment induced 6.4% and 12.3% increases in intracellular reactive oxygen species stained by 5-(and 6)-carboxyl-2′,7′-dichlorodihydrofluorescein diacetate and dihydrorhodamine 123, respectively. Since malignant melanomas are known to have high HSP70 expression and iNO activity, the suppressive effects of cFIR on HSP70 and NO may warrant future interest in antitumor applications.

Biological effects of insulin on murine melanoma cells and fish erythrophoroma cells: A comparative study

2008 ◽  
Vol 156 (2) ◽  
pp. 218-223 ◽  
Author(s):  
Adriana Luchs ◽  
Doris Hissako Sumida ◽  
Maria Aparecida Visconti ◽  
Ana Maria de Lauro Castrucci
Keyword(s):  
Comparative Study ◽  
Biological Effects ◽  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

scholarly journals Anthocyanin determination in blueberry extracts from various cultivars and their antiproliferative and apoptotic properties in B16-F10 metastatic murine melanoma cells

2013 ◽  
Vol 95 ◽  
pp. 436-444 ◽  
Author(s):  
Andrea Bunea ◽  
Dumitriţa Rugină ◽  
Zoriţa Sconţa ◽  
Raluca M. Pop ◽  
Adela Pintea ◽  
...  
Keyword(s):  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Regulation of c-met expression in B16 murine melanoma cells by melanocyte stimulating hormone

1999 ◽  
Vol 112 (5) ◽  
pp. 623-630
Author(s):  
D. Rusciano ◽  
P. Lorenzoni ◽  
M.M. Burger
Keyword(s):  
Melanoma Cells ◽  
Parental Cell ◽  
Melanocortin Receptor ◽  
Parental Cell Line ◽  
Melanocyte Stimulating Hormone ◽  
Murine Melanoma ◽  
The One ◽  
Murine Melanoma Cells ◽  
Stimulating Hormone

B16 murine melanoma cells selected in vivo for enhanced liver metastatic ability (B16-LS9) show on the one hand an increased expression and constitutive activation of the proto-oncogene c-met (the receptor for hepatocyte growth factor/scatter factor), and on the other hand a more differentiated phenotype, when compared to the parental cell line, B16-F1. Following this observation, we have tried to establish whether there is a direct relationship between differentiation and c-met expression in B16 melanoma cells. Treatment of these cells with differentiating agents indicated that c-met expression was strongly induced by melanocyte stimulating hormone, while retinoic acid had almost no influence. c-met induction was triggered by engagement of the melanocortin receptor, cAMP elevation and PKA/PKC(α) activation, as respectively shown by the effects of ACTH, cAMP elevating agents and specific PK inhibitors. Regulation of c-met expression via the melanocortin receptor and cAMP raises the intriguing possibility that autocrine and/or paracrine mechanisms acting in vivo on this circuit might influence (through c-met expression and activation) the metastatic behavior of these tumor cells, which we have shown to be dependent on their c-met expression.

scholarly journals P-Selectin-Mediated Platelet Adhesion Promotes the Metastasis of Murine Melanoma Cells

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e91320 ◽  
Author(s):  
Cui-Ling Qi ◽  
Bo Wei ◽  
Jie Ye ◽  
Yang Yang ◽  
Bin Li ◽  
...  
Keyword(s):  
Platelet Adhesion ◽  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells

Surface Antigens of Murine Melanoma Cells

1984 ◽  
pp. 51-67
Author(s):  
Douglas M. Gersten ◽  
Vincent J. Hearing ◽  
John J. Marchalonis
Keyword(s):  
Surface Antigens ◽  
Melanoma Cells ◽  
Murine Melanoma ◽  
Murine Melanoma Cells
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