Necrotizing Fasciitis and Toxic Shock Syndrome fromClostridium septicumfollowing a Term Cesarean Delivery

Necrotizing fasciitis and toxic shock syndrome are life-threatening conditions that can be seen after any surgical procedure. With only 4 previous published case reports in the obstetrics and gynecology literature of these two conditions occurring secondary toClostridium septicum, we describe a case of necrotizing fasciitis and toxic shock syndrome occurring after a term cesarean delivery caused by this microorganism, requiring aggressive medical and surgical intervention.

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Periocular Necrotizing Fasciitis with Toxic Shock Syndrome

Case Reports in Ophthalmology ◽

10.1159/000488971 ◽

2018 ◽

Vol 9 (2) ◽

pp. 299-303

Author(s):

Tri Rejeki Herdiana ◽

Yasuhiro Takahashi ◽

Ma. Regina Paula Valencia ◽

Marian Grace Ana-Magadia ◽

Hirohiko Kakizaki

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Necrotizing Fasciitis ◽

Toxic Shock Syndrome ◽

Surgical Intervention ◽

High Dose ◽

Toxic Shock ◽

Intravenous Antibiotic ◽

High Level ◽

Prompt Diagnosis

Purpose: To report a case of periocular necrotizing fasciitis with toxic shock syndrome. Methods: This is a case report of a previously healthy 69-year-old woman with left preseptal eyelid infection that spread rapidly and deteriorated into necrosis of the eyelid with toxic shock syndrome. She was admitted to intensive care unit for hemodynamic stabilization. Results: Intravenous antibiotic and high-dose immunoglobulin were administered followed by surgical debridement. Rehabilitative eyelid reconstruction was performed after acute episode, resulting in patient satisfaction in relation to periocular function and appearance. Conclusion: We reported a case of periocular necrotizing fasciitis with toxic shock syndrome that necessitated early aggressive medical treatment and adequate surgical intervention to decrease morbidity and mortality. A high level of suspicion of periocular necrotizing fasciitis is necessary to make a prompt diagnosis.

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Successful Treatment of Streptococcal Toxic Shock Syndrome with Both Diffuse Peritonitis and Necrotizing Fasciitis

Case Reports in Surgery ◽

10.1155/2018/8260968 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Shuichi Sato ◽

Masahiro Ito ◽

Tsuyoshi Sakai ◽

Anri Kaneta ◽

Fumie Sato

Keyword(s):

Mechanical Ventilation ◽

Necrotizing Fasciitis ◽

Toxic Shock Syndrome ◽

Multiple Organ ◽

Streptococcal Toxic Shock Syndrome ◽

Diffuse Peritonitis ◽

Multiple Organ Dysfunction ◽

Toxic Shock ◽

Life Threatening ◽

Uncommon Case

Streptococcal toxic shock syndrome (STSS) is a life-threatening disease caused by infection of beta-hemolytic streptococci. Here, we report an uncommon case of STSS with both diffuse peritonitis and necrotizing fasciitis and summarize previous cases. The patient was diagnosed with STSS due to an infection of the soft tissue of the lower extremity after surgery for diffuse peritonitis. The general condition had rapidly deteriorated with multiple organ dysfunction. Immediate intensive care, including mechanical ventilation, hemodiafiltration, and repeated debridement, is indispensable for a favorable outcome.

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TOXIC-SHOCK SYNDROME AFTER A MINOR SURGICAL PROCEDURE

The Lancet ◽

10.1016/s0140-6736(88)92340-9 ◽

1988 ◽

Vol 332 (8604) ◽

pp. 227

Author(s):

J BROWN

Keyword(s):

Toxic Shock Syndrome ◽

Surgical Procedure ◽

Toxic Shock ◽

A Minor

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Pediatric Rashes

10.2310/em.4414 ◽

2017 ◽

Author(s):

Summer Stears-Ellis

Keyword(s):

Necrotizing Fasciitis ◽

Toxic Epidermal Necrolysis ◽

Toxic Shock Syndrome ◽

Spotted Fever ◽

Rocky Mountain ◽

Stevens Johnson Syndrome ◽

Rocky Mountain Spotted Fever ◽

Toxic Shock ◽

Johnson Syndrome ◽

Schonlein Purpura

Pediatric rashes are a common chief complaint in the emergency department (ED) and a source of anxiety for both parents and providers. Many of these rashes will not require intervention aside from symptomatic relief and parental reassurance. However, there is a subset of rashes that are the result of underlying life-threatening conditions that will warrant immediate intervention and treatment to prevent further deterioration and possible death. This review focuses on outlining the pathology of seven potentially deadly pediatric rashes that ED physicians are likely to encounter, how they present, and how to treat and manage them according to the most recent available guidelines. Figures show primary lesions, pattern of lesions, and distribution of rash associated with bacterial meningitis, toxic shock syndrome (TSS), Rocky Mountain spotted fever, Stevens-Johnson syndrome/toxic epidermal necrolysis, erythema multiforme minor and major, necrotizing fasciitis, and Henoch-Schönlein purpura. Tables list bacterial meningitis antibiotic treatment, Centers for Disease Control and Prevention clinical and laboratory criteria for TSS, TSS antibiotic treatment regimens, scoring systems for toxic epidermal necrolysis and necrotizing fasciitis, and the latest guidelines as of June 2017. This review contains 9 figures, 6 tables, and 50 references. Key words: Pediatric rash, toxic shock syndrome, skin rash, rash distribution, Rocky Mountain spotted fever, Stevens-Johnson syndrome, toxic epidermal necrolysis, necrotizing fasciitis, Henoch-Schönlein purpura

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Streptococcal toxic shock syndrome complicating necrotizing fasciitis in a renal transplant patient

Nephrology Dialysis Transplantation ◽

10.1093/ndt/9.10.1498 ◽

1994 ◽

Keyword(s):

Renal Transplant ◽

Necrotizing Fasciitis ◽

Toxic Shock Syndrome ◽

Renal Transplant Patient ◽

Transplant Patient ◽

Streptococcal Toxic Shock Syndrome ◽

Toxic Shock

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„Tempus fugit, venit mors” – a streptococcalis toxikus sokk szindrómáról egy eset kapcsán

Orvosi Hetilap ◽

10.1556/650.2019.31597 ◽

2019 ◽

Vol 160 (48) ◽

pp. 1887-1893

Author(s):

Bálint Gergely Szabó ◽

Rebeka Kiss ◽

Katalin Szidónia Lénárt ◽

Nikolova Radka ◽

Béla Kádár

Keyword(s):

Toxic Shock Syndrome ◽

Signs And Symptoms ◽

Rapid Progression ◽

Streptococcal Toxic Shock Syndrome ◽

Toxic Shock ◽

Life Threatening Illness ◽

Life Threatening ◽

Group A ◽

High Level ◽

Portal Of Entry

Abstract: Streptococcal toxic shock syndrome (STSS) is a hyperacute, life-threatening illness, a complication of invasive streptococcal (mostly group A, rarely groups B, G or C) infection. There is no portal of entry (skin, vagina, pharynx) in nearly half of the STSS cases. The initial signs and symptoms (fever, flu-like complaints, hypotension) are scarce and aspecific, but because of its rapid progression and poor prognosis, early high level of suspicion is necessary. Management has 3 crucial points: initiation of anti-streptococcal regimen (and intravenous immunoglobulin in some cases), aggressive intensive care support of multi-organ failure, and surgical control of the infective source. In this article, we present a case of a patient succumbing to streptococcal toxic shock syndrome which was preceded by primary S. pyogenes bacteremia, and review the key points of this potentially fatal disease for practising clinicians. Orv Hetil. 2019; 160(48): 1887–1893.

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