scholarly journals Early Glottic Cancer: Role of MRI in the Preoperative Staging

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Eugenia Allegra ◽  
Pierpaolo Ferrise ◽  
Serena Trapasso ◽  
Orazio Trapuzzano ◽  
Antonio Barca ◽  
...  
Keyword(s):  
Prospective Study ◽  
Early Stage ◽  
Anterior Commissure ◽  
Preoperative Staging ◽  
High Specificity ◽  
Clinical Staging ◽  
Glottic Cancer ◽  
Pathology Report ◽  
Supracricoid Laryngectomy ◽  
Early Glottic Cancer

Introduction.Clinical staging is the most important time in management of glottic cancer in early stage (I-II). We have conducted a prospective study to evaluate if magnetic resonance imaging (MRI) is more accurate than computed tomography (CT) about tumoral extension, to exactly choose the most appropriate surgical approach, from organ preservation surgery to demolitive surgery.Materials and Methods.This prospective study was conducted on 26 male patients, with suspected laryngeal neoplasia of glottic region. The images of MRI and CT were analyzed to define the expansion of glottic lesion to anterior commissure, laryngeal cartilages, subglottic and/or supraglottic site, and paraglottic space. The results of MRI and CT were compared with each other and with the pathology report.Results.CT accuracy was 70% with low sensitivity but with high specific value. MRI showed a diagnostic accuracy in 80% of cases, with a sensitivity of 100% and high specificity. Statistical analysis showed that MRI has higher correlation than CT with the pathology report.Conclusion.Our study showed that MRI is more sensitive than CT in the preoperative staging of early glottic cancer, to select exactly the eligible patients in conservative surgery of the larynx, as supracricoid laryngectomy and cordectomy by CO2laser.

Accuracy of flexible versus rigid laryngoscopic photo-documentation in the diagnosis of early glottic cancer

2013 ◽  
Vol 127 (9) ◽  
pp. 890-896 ◽  
Author(s):  
F M Makki ◽  
A Hilal ◽  
E Fung ◽  
R Hart ◽  
S M Taylor ◽  
...  
Keyword(s):  
Image Quality ◽  
Early Stage ◽  
Anterior Commissure ◽  
Glottic Cancer ◽  
Accuracy Rate ◽  
Early Glottic Cancer ◽  
Clinical Accuracy ◽  
Clinical Description ◽  
Accuracy Rates ◽  
Single Blind

AbstractObjective:To compare the image quality provided by rigid laryngoscopes versus flexible distal-chip laryngoscopes when documenting the same laryngeal pathology.Methods:This paper reports a prospective single-blind study. Ten early stage glottic cancer cases were selected. Photographs of the pathologies were taken using both rigid and flexible distal-chip laryngoscopes (a total of 20 photographs). Nineteen clinicians were asked to review the laryngoscopic photographs; the clinicians were provided with a worksheet, which included questions regarding the clinical description, photograph quality and overall satisfaction with the images obtained. Clinicians' responses to the worksheet questions were then analysed.Results:The overall accuracy rate for lesion sidedness, anatomical sub-site involvement, anterior commissure involvement and tumour staging were 94.7 per cent, 46.6 per cent, 53.7 per cent and 47.1 per cent respectively. There were no statistically significant differences in terms of the accuracy rates, photograph quality or overall satisfaction with the photographs obtained by either modality.Conclusion:There were no statistically significant differences demonstrated in overall clinical accuracy or perceived image quality between the use of the rigid or flexible endoscopes when interpreting images of early glottic cancer.

P219 THE ROLE OF PET-CT IN THE EVALUATION OF LYMPH NODE INVOLVEMENT IN ESOPHAGEAL AND GASTROESOPHAGEAL JUNCTION CARCINOMA - A 5-YEAR SINGLE CENTER EXPERIENCE

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
Chrysovalantis Vergadis ◽  
Eustratia Mpaili ◽  
Athanasios Syllaios ◽  
Maria Mpoura ◽  
Adamantios Michalinos ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
False Positive ◽  
Gastroesophageal Junction ◽  
Preoperative Staging ◽  
False Negative ◽  
Clinical Staging ◽  
Lymph Node Status ◽  
Pathology Report ◽  
Pet Ct

Abstract Aim To determine the efficacy of positron emission tomography-computed tomography (PET-CT) in the evaluation of lymph node status during preoperative staging on patients with esophageal and gastrοesophageal junction carcinoma compared to the final histopathological findings. Background & Methods Data on patients that underwent esophagectomy from 01/03/2014 to 01/03/2019 were prospectively collected and retrospectively reviewed. Based on the medical records, the following parameters were extracted and analyzed: patient demographics, histopathological parameters, surgical and oncological outcomes. All patients were staged according to the AJCC 8th edition. Results A total of 79 patients underwent Ivor Lewis or McKeown esophagectomy for either squamous cell carcinoma (n= 7 patients) or adenocarcinoma of esophagus or gastroesophageal junction (n= 72 patients). In 60 cases, clinical staging was conducted without performing PET- CT, while 19 cases underwent PET-CT. Among the 19 patients, 16 (84.2%) were men, and 3 (15.8 %) were women. Mean age was 62 years, (range 41- 72). Mean nodal harvest per patient was 30.6 lymph nodes. Twelve out of 19 patients (63.2%) revealed lymph node invasion, with a mean of 5.6 positive lymph nodes per patient. PET-CT identified the primary tumor in all 19 patients (100%). PET-CT demonstrated 100% compliance with the final histopathological reports regarding N status in only 5 out of 19 cases (26.3%). Four patients were staged as N0 both pre- and postoperatively, while one was deemed positive by PET-CT in right paracardial lymph nodes which was histopathologically confirmed. In other 4 patients (21.1%), PET-CT was 100% false negative, whereas in 3 patients (15.8%) PET-CT was 100% false positive. In the remaining 7 patients, PET-CT findings were in accordance with the pathology report in 7 out of 25 examined lymph node stations, false positive in 9 out of 25 and false negative in 9 out of 25. Conclusion PET-CT seems to have a considerable number of false positive and false negative results in esophageal cancer in our study as far as N-staging is concerned. Further studies with larger sample size are needed to reach more conclusive results.

scholarly journals Involvement of the Anterior Commissure in Early Glottic Cancer (Tis-T2): A Review of the Literature

Cancers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1234 ◽  
Author(s):  
Martine Hendriksma ◽  
Elisabeth V. Sjögren
Keyword(s):  
Anterior Commissure ◽  
Meta Analysis ◽  
Treatment Modalities ◽  
Glottic Cancer ◽  
Inclusion Criteria ◽  
Early Glottic Cancer ◽  
Weighted Averages ◽  
Detailed Classification ◽  
The Impact

Background: The impact of the anterior commissure (AC) involvement on prognosis in laryngeal cancer remains a topic of discussion with inconsistent results in the literature. This review examines AC involvement as a prognostic factor in patients with early glottic cancer (Tis–T2) treated with radiotherapy or transoral laser microsurgery (TLM). Methods: A systematic literature search was performed. Due to the heterogeneity of the data, no meta-analysis was implemented. Weighted averages were calculated if the appropriate data were extractable. Results: Thirty-four studies on radiotherapy and 23 on TLM fit the inclusion criteria. The majority of studies for both radiotherapy (67.7%) and TLM (75.0%) did not report a significant impact on oncological outcomes. Weighted averages were slightly lower in patients with AC involvement. The two studies that applied a more detailed classification showed a significant impact on the amount of AC involvement. Conclusions: Binary variables (yes/no) for AC involvement lead to inconsistent results. Studies that use more detailed classifications of the AC show that there is a significant impact on the outcome. To further elucidate the role of the AC, detailed stratification of tumors involving the AC need to be investigated in further studies for both treatment modalities.

The influence of anterior commissure involvement in early glottic cancer treated with radiation

1986 ◽  
Vol 12 ◽  
pp. 187
Author(s):  
D. Missailidou ◽  
E. Mayer ◽  
P. Rubin ◽  
C. Haie ◽  
J. Norante ◽  
...  
Keyword(s):  
Anterior Commissure ◽  
Glottic Cancer ◽  
Early Glottic Cancer

P143 Importance of Anterior Commissure in Recurrence of Early Glottic Cancer After Laser Endoscopic Resection

2006 ◽  
Vol 132 (8) ◽  
pp. 893
Author(s):  
C. T. Chone ◽  
E. Yonehara ◽  
J. E. Martins ◽  
F. M. Gripp ◽  
A. Altemani ◽  
...  
Keyword(s):  
Endoscopic Resection ◽  
Anterior Commissure ◽  
Glottic Cancer ◽  
Early Glottic Cancer
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