scholarly journals Polyarticular Septic Arthritis Caused byHaemophilus influenzaeSerotype f in an 8-Month-Old Immunocompetent Infant: A Case Report and Review of the Literature

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Raheel Ahmed Ali ◽  
Sheldon L. Kaplan ◽  
Scott B. Rosenfeld
Keyword(s):  
Haemophilus Influenzae ◽  
Septic Arthritis ◽  
Case Reports ◽  
Type B ◽  
Incision And Drainage ◽  
Management Culture ◽  
Left Elbow ◽  
Invasive Infections ◽  
Immunocompetent Infant

Background. The standard use of vaccinations against pathogens has resulted in a decreased incidence of musculoskeletal infections caused by these previously common bacterial pathogens. Consequently, the incidence of infections caused by atypical bacteria is rising. This report presents a case of septic arthritis caused by non-type bH. influenzaein a pediatric patient.Methods. We report a case of an infant with polyarticular septic arthritis caused byH. influenzaeserotype f. A literature review was conducted with the inclusion criteria of case reports and studies published between 2004 and 2013 addressing musculoskeletalH. influenzaeinfections.Results. An 8-month-old female presented with pain and swelling in her right ankle and left elbow. The patient was diagnosed with septic arthritis and underwent incision and drainage. Wound and blood cultures were positive forHaemophilus influenzaeserotype f. In addition to treatment with IV antibiotics, the patient underwent immunocompetency studies, which were normal. Subsequent follow-up revealed eradication of the infection.Conclusions.Haemophilus influenzaenon-type b may cause serious invasive infections such as sepsis or septic arthritis in children with or without predisposing factors such as immunodeficiency or asplenia. Optimal treatment includes surgical management, culture driven IV antibiotics, and an immunologic workup.

scholarly journals Non-Type B Haemophilus influenzae Invasive Infections in North Dakota and South Dakota, 2013–15

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Stephanie Antony ◽  
Ashlesha Kaushik ◽  
Clifford Mauriello ◽  
Archana Chatterjee
Keyword(s):  
Haemophilus Influenzae ◽  
South Dakota ◽  
North Dakota ◽  
Type B ◽  
Invasive Infections

scholarly journals Antibody levels against Streptococcus pneumoniae and Haemophilus influenzae type b in a population of splenectomized individuals with varying vaccination status

1997 ◽  
Vol 119 (2) ◽  
pp. 167-174 ◽  
Author(s):  
H. B. KONRADSEN ◽  
C. RASMUSSEN ◽  
P. EJSTRUD ◽  
J. B. HANSEN
Keyword(s):  
Streptococcus Pneumoniae ◽  
Haemophilus Influenzae ◽  
Vaccine Coverage ◽  
Pneumococcal Vaccination ◽  
Haemophilus Influenzae Type ◽  
Type B ◽  
Serious Infections ◽  
Antibody Levels

In order to determine antibody levels against Streptococcus pneumoniae (pneumococcus) and Haemophilus influenzae type b (Hib) in a population of splenectomized subjects, 561 persons in a Danish county, splenectomized between 1984 and 1993 were identified. Two hundred and thirty-five were alive and 149 participated in the study. Each person donated a blood sample for antibody determination by ELISA. Though vaccine coverage among the 149 persons was 91% only 52% had ‘protective’ levels of pneumococcal antibodies. Despite recommendations for regular follow-up on pneumococcal antibody levels this had only been carried out in 4% of the subjects. Splenectomized subjects who needed pneumococcal revaccination were significantly more likely to have received their initial vaccination less than 14 days before or after splenectomy, as recommended, than those not requiring revaccination. Therefore, the timing of initial pneumococcal vaccination in relation to splenectomy seems to be important. All persons had Hib antibody levels higher than 0·15 μg/ml and 60% had levels higher than 1 μg/ml, which are the levels thought to provide short term and long term protection, respectively. In total, 37% of the 149 persons tested had pneumococcal and Hib antibody levels thought to correlate with protection from serious infections.

Follow-Up of Cases of Haemophilus influenzae Type b Meningitis to Determine Its Long-Term Sequelae

2013 ◽  
Vol 163 (1) ◽  
pp. S44-S49 ◽  
Author(s):  
A.S.M. Nawshad Uddin Ahmed ◽  
Naila Z. Khan ◽  
Manzoor Hussain ◽  
M. Ruhul Amin ◽  
Mohammed Hanif ◽  
...  
Keyword(s):  
Haemophilus Influenzae ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B

Haemophilus influenzae Type b in a Nursery School: The Value of Biotyping

PEDIATRICS ◽  
1982 ◽  
Vol 69 (2) ◽  
pp. 215-218
Author(s):  
Charles G. Prober ◽  
Moshe M. Ipp ◽  
Robert M. Bannatyne
Keyword(s):  
Haemophilus Influenzae ◽  
Nursery School ◽  
Colonization Rate ◽  
Haemophilus Influenzae Type ◽  
Type B ◽  
Nasal Swabs ◽  
Serotype B ◽  
Culture Site

Meningitis due to Haemophilus influenzae serotype b biotype II occurred in a 2-year-old child who attended a nursery school along with 26 other 2-year-old children. Nasal swabs from these 26 contacts revealed a H influenzae type b colonization rate of 50% (13/26); simultaneously performed throat swabs detected a colonization rate of 4% (1/26). Biotyping of the H influenzae type b isolates revealed that only 46% (6/13) were the same biotype as the index case; the remaining seven isolates were biotype III. All children received treatment with 20 mg/kg/day of rifampin administered by the nursery school attendant as a single dose for four days before the results of the cultures were known. Eradication of H influenzae type b carriage was successful in three of the six biotype II carriers and five of the six biotype III carriers available for follow-up culture. It was concluded that: (1) the culture site utilized in determining H influenzae type b colonization rates may markedly influence the results obtained, (2) biotyping may be a valuable epidemiologic tool in investigating the contacts of patients with H influenzae type b disease, and (3) failures of rifampin to eradicate the carriage of H influenzae type b from the nasopharynx may occur. The prudent approach to the management of young contacts of patients with serious H influenzae type b disease is to recognize their high risk status and to maintain close surveillance of them. The role of chemoprophylaxis with rifampin remains mains to be established.

Comparison of Rifampin and Ampicillin in Day Care Center Contacts of Haemophilus influenzae Type b Disease

PEDIATRICS ◽  
1980 ◽  
Vol 66 (1) ◽  
pp. 1-4
Author(s):  
Charles Gessert ◽  
Dan M. Granoff ◽  
Janet Gilsdorf
Keyword(s):  
Haemophilus Influenzae ◽  
Day Care ◽  
Care Center ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Type B ◽  
Day Care Center ◽  
Randomized Crossover Trial ◽  
Culture Positive

A prospective, randomized, crossover trial was conducted comparing therapy with rifampin to therapy with ampicillin in eradicating Haemophilus influenzae type b carriage. Twenty-eight carriers were identified in a day care center following exposure to a patient with H influenzae type b meningitis; 26 children were randomly assigned to treatment with either ampicillin (100 mg/kg for five days) or rifampin (20 mg/kg for four days). Cultures were repeated two and four days after discontinuing therapy. In the initial trial, 6/17 children (35%) remained culture positive after treatment with ampicillin compared to 0/9 children treated with rifampin (P = .106). The six children who were ampicillin treatment failures had H influenzae type b isolates sensitive to that drug. These children were subsequently treated with rifampin and their cultures became negative. (For both trials, P = .027.) Repeat cultures 30 days after therapy in 20 treated children revealed one culture positive for H influenzae type b. No further cases developed in the day care center (four months of follow-up). These data suggest that rifampin may be more effective than ampicillin in chemoprophylaxis of contacts of H influenzae type b disease.

Sign in / Sign up

Export Citation Format

Share Document