scholarly journals Gastric Cancer in the Excluded Stomach 10 Years after Gastric Bypass

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Augusto Tinoco ◽  
Lorena F. Gottardi ◽  
Eduardo D. Boechat
Keyword(s):  
Gastric Cancer ◽  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Gastric Adenocarcinoma ◽  
Rare Condition ◽  
Gastric Lesions ◽  
Common Cause ◽  
Health Authorities ◽  
Excluded Stomach ◽  
Related Mortality

According to the Brazilian health authorities, around 2,000 new cases of gastric cancer emerge in Brazil per year (Instituto Nacional de Câncer José Alencar Gomes da Silva, 2014). Indeed, gastric cancer constitutes the second most common cause of cancer-related mortality worldwide and 95% of such malignancies are adenocarcinomas (De Roover et al., 2006, and Clark et al., 2006). Roux-en-Y gastric bypass (RYGB) is a procedure frequently employed in bariatric surgery but restricted access to the excluded stomach means that discovery of gastric lesions is difficult, and diagnosis and treatment may be delayed. We report herein a case of gastric adenocarcinoma in the excluded stomach of a patient submitted to RYGB with the purpose of illustrating the difficulty of diagnosing and treating this rare condition.

scholarly journals Gastric Pouch Mixed Adenoneuroendocrine Carcinoma With a Mixed Adenocarcinoma Component After Roux-en-Y Gastric Bypass

2017 ◽  
Vol 5 (4) ◽  
pp. 232470961774090 ◽  
Author(s):  
Ricardo G. Pastorello ◽  
Mariana Petaccia de Macedo ◽  
Wilson Luiz da Costa Junior ◽  
Maria Dirlei F. S. Begnami
Keyword(s):  
Bariatric Surgery ◽  
Gastric Bypass ◽  
Gastric Pouch ◽  
Unique Case ◽  
Rare Type ◽  
Mixed Adenoneuroendocrine Carcinoma ◽  
Early Cancer Diagnosis ◽  
Excluded Stomach ◽  
Cell Components ◽  
Adenocarcinoma Component

The Roux-en-Y gastric bypass is one of the most common procedures currently performed for surgical treatment of patients with severe obesity. Gastric cancer after bariatric surgery is not common, with most of them arising in the excluded stomach. Gastric mixed adenoneuroendocrine carcinomas are a rare type of stomach malignancy, composed of both adenocarcinoma and neuroendocrine tumor-cell components, with the latter comprising at least 30% of the whole neoplasm. In this article, we report a unique case of a mixed adenoneuroendocrine carcinoma with a mixed adenocarcinoma (tubular and poorly cohesive) component arising in the gastric pouch of a patient who underwent previous Roux-en-Y gastric bypass for glycemic control. Since stomach cancer is not usual in patients who have formerly undergone bariatric surgery and symptoms tend to be nonspecific, such diagnosis is often rendered at an advanced stage. Full assessment of these patients when presenting such vague symptoms is critical for an early cancer diagnosis.

A Novel Endoscopic Technique to Diagnose Gastric Cancer in the Excluded Stomach After Roux-en-Y Gastric Bypass

2017 ◽  
Vol 112 ◽  
pp. S1148-S1149
Author(s):  
Saeed Ali ◽  
Abdelkader Chaar ◽  
Wesam Frandah ◽  
Muhammad Khalid Hasan
Keyword(s):  
Gastric Cancer ◽  
Gastric Bypass ◽  
Endoscopic Technique ◽  
Excluded Stomach

scholarly journals Primary Coronary Embolism as an Unusual Manifestation of Nonbacterial Thrombotic Endocarditis in a Patient with Gastric Cancer

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Giovanni Ferlan ◽  
Annalisa Fiorella ◽  
Claudio De Pasquale ◽  
Francesco Tunzi
Keyword(s):  
Gastric Cancer ◽  
Gastric Adenocarcinoma ◽  
Clinical Condition ◽  
Clinical Symptoms ◽  
Thromboembolic Complications ◽  
Unusual Manifestation ◽  
Common Cause ◽  
Nonbacterial Thrombotic Endocarditis ◽  
Coronary Embolism ◽  
Intrinsic Condition

Nonbacterial thrombotic endocarditis (NBTE) is a rare clinical condition characterized by the presence of sterile vegetations on valvular leaflets Gross and Friedberg (1936). The most frequent cause of NBTE is antiphospholipid syndrome Hughson and et al. (1993); malignancy, through an intrinsic condition of hypercoagulability, is the second most common cause Thomas (2001). Systemic thromboembolic complications are frequently associated with this condition, but coronary embolism is not common. We report the case of a patient with NBTE secondary to gastric adenocarcinoma with clinical symptoms of coronary and systemic emboli.

scholarly journals GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location

2018 ◽  
Author(s):  
Mário S. De Souza Albuquerque ◽  
Antônio F. Da Silva-filho ◽  
Marina Ferraz Cordeiro ◽  
Maria de Fátima Deodato de Souza ◽  
Michael W.L. Quirino ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Total Gastrectomy ◽  
Gastric Adenocarcinoma ◽  
Histological Grade ◽  
Tissue Expression ◽  
Positive Staining ◽  
Tissue Architecture ◽  
Common Cause ◽  
The World ◽  
Differential Tissue

Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of ppGalNAc-T15 and to evaluate its possible association with clinical-pathological parameters and outcome of gastric adenocarcinoma patients. For these 70 patients were evaluated the expression by immunohistochemistry to ppGalNAc-T15. Our results showed that 33 (47.1%) patients were ppGalNAC-T15+ positive and 37 (52.9%) negative. Positive staining for ppGalNAc-T15 was significantly present in patients older than 60 years (P=0.0306) and submitted to total gastrectomy (P=0.0087). Also, some results remained at the limit of significance as surgical standing (P=0.0562) and histological grade (P=0.0549). Therefore, the ppGalNAc-T15 immunoreactivity can be useful to understand the prognosis of patients with gastric cancer.

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