scholarly journals Recurrence of Prostate Cancer with Cutaneous Metastasis after Radical Prostatectomy

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Parth Patel ◽  
Jay Patel ◽  
Sameer Siddiqui

While cutaneous metastases are already extremely rare in primary metastatic prostatic adenocarcinoma, cutaneous manifestations in recurrent prostate cancer have rarely been described prior to this report. Here we present the case report of a 93-year-old male who underwent radical prostatectomy but eventually suffered from a previously undescribed recurrence of prostatic adenocarcinoma with distant cutaneous metastases to proximal right lower leg.

2021 ◽  
Vol 9 ◽  
pp. 232470962199076
Author(s):  
Alexander Dills ◽  
Okechukwu Obi ◽  
Kevin Bustos ◽  
Jesse Jiang ◽  
Shweta Gupta

Prostate cancer is the most common cancer affecting men in the United States and the second greatest cause of cancer-related death. Metastases usually occur to bone followed by distant lymph nodes and then viscera. Cutaneous metastases are extremely rare. Their presence indicates advanced disease and a poor prognosis. As they are highly variable in appearance and may mimic a more benign process, biopsy is essential for identification. Serine proteases, particularly human tissue kallikreins, may play an important role in promoting metastasis and facilitate infiltration of the skin. Individual cancer genetics may predispose to more aggressive cancer and thus earlier and more distant metastases. In this article, we report our case of a 67-year-old man with a 4-year history of castrate-resistant prostate cancer with cutaneous metastases confirmed by histology. Despite multiple lines of systemic therapy, the patient suffered progressive disease with worsening performance status and was enrolled in hospice.


2016 ◽  
Vol 15 (3) ◽  
pp. e431
Author(s):  
P. Dell'Oglio ◽  
N. Suardi ◽  
S. Boorjian ◽  
N. Fossati ◽  
G. Gandaglia ◽  
...  

2001 ◽  
Vol 166 (3) ◽  
pp. 882-886 ◽  
Author(s):  
ERIK T. GOLUBOFF ◽  
DIANE PRAGER ◽  
DANIEL RUKSTALIS ◽  
BRUCE GIANTONIO ◽  
MARTIN MADORSKY ◽  
...  

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