Spontaneous Renal Artery Dissection in a Patient with Neurofibromatosis Type I

We present a case of spontaneous renal artery dissection (SRAD) in a 28-year-old female with history of neurofibromatosis type I (NF-1) treated successfully with endovascular stenting. The clinical presentation, diagnostic testing, and treatment options are discussed. An endovascular approach with stenting was successfully performed after failure of medical treatment with subcutaneous low molecular weight heparin. Patient’s blood pressure and symptoms improved significantly. This may be the first reported case of SRAD in a patient with NF-1 successfully treated with endovascular stenting.

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Glioblastoma in the Cerebellopontine Angle in a Patient with Neurofibromatosis Type I: A Case Report and Review of the Literature

Annals of Otology and Neurotology ◽

10.1055/s-0040-1708563 ◽

2019 ◽

Vol 2 (02) ◽

pp. 72-75

Author(s):

Mohammad Kareem Shukairy ◽

Andrea M. Ziegler ◽

Douglas E. Anderson ◽

John P. Leonetti

Keyword(s):

Case Report ◽

Cerebellopontine Angle ◽

Malignant Tumors ◽

Neurofibromatosis Type ◽

Type I ◽

Neurofibromatosis Type I ◽

Increased Risk ◽

Facial Numbness ◽

History Of ◽

Pain Patients

Abstract Introduction Glioblastoma multiforme (GBM) is the most common primary brain malignancy in adults and is typically in the supratentorial cerebral hemispheres. It has been reported to occur in the posterior fossa at the cerebellopontine angle (CPA), but the incidence is extremely rare. Case Report We report a case of a patient with a history of neurofibromatosis type I (NFI) diagnosed with a GBM arising in the CPA after presenting with facial numbness and pain. Patients with NFI are known to have an increased risk of developing both benign and malignant tumors, including a propensity for brainstem gliomas. However, there is no known association between NFI and tumors of the CPA. We believe this is the first reported case of a GBM of the CPA in a patient with NFI. Conclusion Although rare, GBM should be included in the differential diagnosis of a patient with a CPA tumor, especially in patients with increased risk of malignant pathology.

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Renal Artery Aneurysm at the Hilum Secondary to Neurofibromatosis Type I

European Journal of Vascular and Endovascular Surgery ◽

10.1016/j.ejvs.2015.01.022 ◽

2015 ◽

Vol 49 (4) ◽

pp. 464 ◽

Cited By ~ 2

Author(s):

X. Gui ◽

Y. Zheng

Keyword(s):

Renal Artery ◽

Artery Aneurysm ◽

Neurofibromatosis Type ◽

Type I ◽

Renal Artery Aneurysm ◽

Neurofibromatosis Type I

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Efficacy of denosumab therapy for neurofibromatosis type I with osteoporosis and history of fractures: a case report

Therapeutics and Clinical Risk Management ◽

10.2147/tcrm.s159668 ◽

2018 ◽

Vol Volume 14 ◽

pp. 1243-1246 ◽

Cited By ~ 4

Author(s):

Masashi Uehara ◽

Yukio Nakamura ◽

Jun Takahashi ◽

Mikio Kamimura ◽

Fumihiro Isobe ◽

...

Keyword(s):

Case Report ◽

Neurofibromatosis Type ◽

Type I ◽

Neurofibromatosis Type I ◽

History Of

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Ruptured inferior mesenteric artery aneurysm in a patient with neurofibromatosis type I and its management

International Surgery Journal ◽

10.18203/2349-2902.isj20180384 ◽

2018 ◽

Vol 5 (2) ◽

pp. 732

Author(s):

Srushti Sheth ◽

Nirajan Kansakar ◽

Premnarayan Agarwal ◽

Rajdeep Singh ◽

Anurag Mishra

Keyword(s):

Mesenteric Artery ◽

Inferior Mesenteric Artery ◽

Iliac Fossa ◽

Treatment Options ◽

Lower Abdominal Pain ◽

Artery Aneurysm ◽

Neurofibromatosis Type ◽

Type I ◽

Neurofibromatosis Type I ◽

Left Iliac Fossa

Inferior mesenteric artery aneurysm is very rare and are usually asymptomatic. A high mortality is associated with aneurysmal rupture. The purpose of this paper is to report occurrence of a rare disease and its treatment options. A 64 years old woman presented with complaints of lower abdominal pain radiating to back for 1month, with non-passage of stools for 5days, and had decreased appetite. She had features of Neurofibromatosis type I. On examination, she had tachycardia and had pallor, and abdominal examination showed lumps in right and left iliac fossa which progressively increased in size. Computed tomography scan showed features of leaking inferior mesenteric artery aneurysm with perianeurysmal hematoma. The patient was taken up for surgical exploration wherein after checking the bowel viability, the inferior mesenteric artery was clipped at its origin, ligated and divided followed by hematoma evacuation. Post-operative stay was uneventful, and the patient was discharged on post-operative day 10.

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Sepsis from Neurofibromatosis

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques ◽

10.1017/s0317167100005242 ◽

2006 ◽

Vol 33 (3) ◽

pp. 328-328

Author(s):

Navdeep Tangri ◽

Shireen Sirhan ◽

Gordon Crelinsten

Keyword(s):

Autosomal Dominant ◽

Clinical Manifestations ◽

Neurofibromatosis Type ◽

Large Mass ◽

Type I ◽

Neurofibromatosis Type I ◽

Autosomal Dominant Disorder ◽

Chest Wound ◽

History Of ◽

The Right

Neurofibromatosis Type I or von Recklinghausen’s neurofibromatosis is an autosomal dominant disorder with a high index of spontaneous mutations and extremely varied and unpredictable clinical manifestations. We present a case of sepsis secondary to an infected hematoma, enclosed within a massive neurofibroma.A 42-year-old man presented to the emergency department with a one week history of fever and chills. He reported an increase in pain and size of a growth near his chest. The patient was noted to be febrile on arrival. On physical examination, a very large neurofibroma was seen extending from the right upper chest. Wound and blood cultures were obtained. Computed Tomography (CT) of the thorax revealed a hematoma contained within the large mass.

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Lung Cancer Associated with Neurofibromatosis Type I

Case Reports in Radiology ◽

10.1155/2013/869793 ◽

2013 ◽

Vol 2013 ◽

pp. 1-3 ◽

Cited By ~ 1

Author(s):

Anastasia Oikonomou ◽

Dimitrios Mikroulis ◽

Paraskevi Mintzopoulou ◽

Lawal Lukman ◽

Panos Prassopoulos

Keyword(s):

Lung Cancer ◽

Case Reports ◽

Ground Glass Opacity ◽

Neurofibromatosis Type ◽

Middle Lobe ◽

Type I ◽

Neurofibromatosis Type I ◽

Lung Cysts ◽

History Of ◽

Well Differentiated

Lung cancer associated with neurofibromatosis type I is considered very rare, and only a few case reports have been described in the literature. There is some evidence that a genetic linkage between neurofibromatosis and carcinogenesis in the lung may exist. We present a 42-year-old female, lifetime nonsmoker with a known history of neurofibromatosis type I, free of respiratory symptoms, who underwent a low-dose HRCT of the lungs to investigate any occult interstitial lung changes. A solitary ill-defined nodule of a ground-glass opacity was detected incidentally in the middle lobe with no associated lymphadenopathy or metastatic disease. Several thin-walled lung cysts were also seen in the lower lobes. Histological analysis of the nodule after middle lobectomy revealed well-differentiated adenocarcinoma. The patient did not receive systemic chemotherapy or radiotherapy. She was free of disease on 18-month followup.

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