scholarly journals Endoscopic Observation of the Growth Process of a Right-Side Sessile Serrated Adenoma/Polyp with Cytological Dysplasia to an Invasive Submucosal Adenocarcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Kaoru Omori ◽  
Kanako Yoshida ◽  
Sadafumi Tamiya ◽  
Tsutomu Daa ◽  
Masahiro Kan

A sessile serrated adenoma/polyp (SSA/P) with cytological dysplasia in the right colon, which transformed to an invasive submucosal adenocarcinoma finally, was endoscopically observed in a 76-year-old woman. A whitish soft SSA/P (approximately 25 mm in diameter) was detected in the cecum. Biopsy samples were obtained from the small nodule, and the lesion was eventually diagnosed as an SSA/P with cytological dysplasia, considering endoscopic observations, among which the narrow-band imaging features suggested that the lesion was adenomatous, that is, a round-oval pattern, and hyperplastic, that is, comprising a circular pattern with dots and an invisible capillary vessel. After 11 months, an SSA/P had rapidly developed into a submucosal adenocarcinoma with lymphatic infiltrations, and the most aggressive deep invasion was observed in the central depression. This case suggests that right-side SSA/Ps with cytological dysplasia should be removed immediately, considering the potential for rapid progression to a larger size and eventually to deep and extensive cancer.

2019 ◽  
Vol 94 (1) ◽  
pp. 56-57
Author(s):  
Fusako Takahashi ◽  
Hiroshi Kashimura ◽  
Akari Munakata ◽  
Naoaki Konno ◽  
Koji Takahashi ◽  
...  

Endoscopy ◽  
2021 ◽  
Author(s):  
Sophie Geyl ◽  
Jérémie Albouys ◽  
Romain Legros ◽  
Hugo Lepetit ◽  
Martin Dahan ◽  
...  

2018 ◽  
Vol 33 (2) ◽  
pp. 466-474 ◽  
Author(s):  
Li-Chun Chang ◽  
Chia-Hung Tu ◽  
Been-Ren Lin ◽  
Chia-Tung Shun ◽  
Weng-Feng Hsu ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Naohisa Yoshida ◽  
Yutaka Inada ◽  
Ritsu Yasuda ◽  
Takaaki Murakami ◽  
Ryohei Hirose ◽  
...  

Background and Aims. Missed polyps are a pitfall of colonoscopy. In this study, we analyzed the efficacy of an additional 30 seconds observation using linked color imaging (LCI) for detecting adenoma and sessile serrated adenoma/polyp (SSA/P). Materials and Methods. We enrolled patients undergoing colonoscopy from February to October 2017 in two institutions. In all patients, the cecum and ascending colon were observed with white light imaging (WLI) first. The colonoscope was inserted again, and the cecum and ascending colon were observed for an additional 30 seconds using either LCI or WLI. The method for the 30 sec observation was to insufflate the cecum and ascending colon sufficiently and observe them in a distant view, because the length of the second observation was determined to be precisely 30 sec. For the second observation, LCI was performed for the first 65 patients and WLI for the next 65. Adenoma and SSA/P detection rate (ASDR) in the second observation were examined in both groups. According to a pilot study, the sample size was estimated 65. Results. In the first observation, ASDR were 30.7% in the LCI group and 32.2% in the WLI group (p=0.85). For the second observation, 13 polyps were detected in the LCI group and 5 polyps in the WLI group (p=0.04). Additionally, ASDR for the second observation were 18.5% and 6.1%, respectively (p=0.03). There were no significant differences between the LCI and WLI groups with respect to morphology (ratio of polypoid) (38.5% versus 60.0%, p=0.52) and histology (ratio of adenoma) (92.3% versus 100.0%, p=0.91). Total adenoma and SSA/P number were 48 in the LCI group and 36 in the WLI group (p=0.02). Conclusion. The 30 seconds additional observation with LCI improved the detection of adenoma and SSA/P in the right-sided colon.


2019 ◽  
Vol 114 (1) ◽  
pp. S80-S80
Author(s):  
Takashi Murakami ◽  
Naoto Sakamoto ◽  
Hirofumi Fukushima ◽  
Hiroya Ueyama ◽  
Tomoyoshi Shibuya ◽  
...  

Author(s):  
N. V. Ageykina ◽  
E. D. Fedorov ◽  
N. A. Oleynikova ◽  
O. A. Kharlova ◽  
N. V. Danilova ◽  
...  

Aim. An illustration of a case of diminutive sessile serrated adenoma (SSA) as a variant of the development of the normal colon mucosa.Materials and methods. In 2017 a diminutive SSA was identified in the case of a 77 year-old patient. During endoscopic examination, which included white light endoscopy examination, narrow band imaging (NBI) and near focus, the main endoscopic signs of SSA were determined. Endoscopic removal of the lesion with subsequent confirmation of its histological structure was performed.Results. The colonoscopy revealed a diminutive SSA of up to 3mm in size with typical endoscopic signs: a flat-elevated type 0-IIA, a “mucinous cap”, the same color to the surrounding mucosa, pit pattern type II-О, absence of meshed capillary vessels, but with isolated dilated capillaries. Histological examination revealed the crypts to have a cytoplasmic-type serration, drop-like expansion and horizontal growth of the basal parts, without epithelial dysplasia.Conclusion. The presented clinical case shows a rare observation of a diminutive SSA, and the complexity of endoscopic diagnosis due to its small size. The above observation demonstrates one of the pathways — developing directly from the normal mucosa, bypassing the stage of hyperplastic polyp. Thus indicating the need for further study of serrated polyps, morphogenesis mechanisms and precancerous potential.


2016 ◽  
Vol 83 (5) ◽  
pp. AB231-AB232
Author(s):  
Shawn Kaye ◽  
Mohit Mittal ◽  
Katherine Kim ◽  
William E. Karnes

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