scholarly journals A rare practice case — a diminutive sessile serrated adenoma of the colon

2020 ◽  
pp. 93-96
Author(s):  
N. V. Ageykina ◽  
E. D. Fedorov ◽  
N. A. Oleynikova ◽  
O. A. Kharlova ◽  
N. V. Danilova ◽  
...  
Keyword(s):  
Narrow Band Imaging ◽  
Normal Mucosa ◽  
Endoscopic Examination ◽  
Histological Structure ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Serrated Polyps ◽  
White Light Endoscopy ◽  
Normal Colon Mucosa ◽  
Elevated Type

Aim. An illustration of a case of diminutive sessile serrated adenoma (SSA) as a variant of the development of the normal colon mucosa.Materials and methods. In 2017 a diminutive SSA was identified in the case of a 77 year-old patient. During endoscopic examination, which included white light endoscopy examination, narrow band imaging (NBI) and near focus, the main endoscopic signs of SSA were determined. Endoscopic removal of the lesion with subsequent confirmation of its histological structure was performed.Results. The colonoscopy revealed a diminutive SSA of up to 3mm in size with typical endoscopic signs: a flat-elevated type 0-IIA, a “mucinous cap”, the same color to the surrounding mucosa, pit pattern type II-О, absence of meshed capillary vessels, but with isolated dilated capillaries. Histological examination revealed the crypts to have a cytoplasmic-type serration, drop-like expansion and horizontal growth of the basal parts, without epithelial dysplasia.Conclusion. The presented clinical case shows a rare observation of a diminutive SSA, and the complexity of endoscopic diagnosis due to its small size. The above observation demonstrates one of the pathways — developing directly from the normal mucosa, bypassing the stage of hyperplastic polyp. Thus indicating the need for further study of serrated polyps, morphogenesis mechanisms and precancerous potential.

scholarly journals A retrospective study on pathological and clinical characteristics of 52 cases with the colorectal serrated polyp

2018 ◽  
Vol 35 (1) ◽  
Author(s):  
Xu Li Hua ◽  
Li Qian Jun ◽  
Shen Xiao Feng ◽  
Da Jing ◽  
Zhu Ya Wen
Keyword(s):  
Retrospective Study ◽  
Clinical Characteristics ◽  
Endoscopic Examination ◽  
Malignant Potential ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Serrated Polyps ◽  
Creative Commons ◽  
Serrated Polyp ◽  
Open Access Article

Background and Objective: Colorectal serrated polyp is considered as histologically heterogeneous lesions with malignant potential. The aim of the study was to evaluate the endoscopic, clinic and pathologic characteristics of colorectal serrated polyps. Methods: The endoscopic, clinic and pathologic characteristics of 52 cases with colorectal serrated polyps between January 2014 and May 2018 in our hospital were analyzed. retrospectively. Results: The prevalence of serrated polyps was 0.39% (52/13,346). The proportions of hyperplastic polyp (HP), sessile serrated adenoma/polyp (SSA/P), and traditional serrated adenoma (TSA) of all serrated polyps were 61.5%, 17.3%, and 21.2%, respectively, which showed a lower proportion of TSA and SSA/P and a higher proportion of HP. Conclusions: The overall detection rate of colorectal serrated polyps was relatively low, and it is necessary to discriminate between SSAPs and HPs during endoscopic examination because of the malignant potential. How to cite this:Hua XL, Jun LQ, Feng SX, Jing D, Wen ZY. A retrospective study on pathological and clinical characteristics of 52 cases with the colorectal serrated polyp. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.238 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Efficacy of Virtual Chromoendoscopy in the Diagnosis of Portal Hypertensive Gastropathy

2016 ◽  
Vol 25 (3) ◽  
pp. 289-293
Author(s):  
Anda Carmen Achim ◽  
Stefan Cristian Vesa ◽  
Eugen Dumitru
Keyword(s):  
Diagnostic Criteria ◽  
White Light ◽  
Narrow Band Imaging ◽  
Endoscopic Examination ◽  
Kappa Statistics ◽  
Portal Hypertensive Gastropathy ◽  
Mosaic Pattern ◽  
White Light Endoscopy ◽  
A New Technique ◽  
Virtual Chromoendoscopy

Background: Diagnosis of portal hypertensive gastropathy (PHG) is based on endoscopic criteria. I-scan technology, a new technique of virtual chromoendoscopy, increases the diagnostic accuracy for lesions in the gastrointestinal tract. Aim: To establish the role of i-scan endoscopy in the diagnosis of PHG. Method: In this prospective study, endoscopic examination was conducted first by using white light and after that i-scan 1 and i-scan 2 technology in a group of 50 consecutive cirrhotic patients. The endoscopic diagnostic criteria for PHG followed the Baveno criteria. The interobserver agreement between white light endoscopy and i-scan endoscopy was determined using Cohen’s kappa statistics. Results: Forty-five of the 50 patients met the diagnostic criteria for PHG when examined by i-scan endoscopy and 39 patients were diagnosed with PHG by white light endoscopy. The strength of agreement between the two methods for the diagnosis of PHG was moderate (k=0.565; 95%CI 0.271-0.859; p<0.001). I-scan 1 classified the mosaic pattern better than classic endoscopy; i-scan 2 described better the red spots. Conclusion: I-scan examination increased the diagnostic sensitivity of PHG. The diagnostic criteria (mosaic pattern and red spots) were easier to observe endoscopically using i-scan than in white light.Abbreviations: FICE: Fuji Intelligent chromoendoscopy; GAVE: gastric antral vascular ectasia; NBI: narrow band imaging; PHG: portal hypertensive gastropathy; PHT: portal hypertension; UGIB: upper gastrointestinal bleeding.

scholarly journals Endoscopic Observation of the Growth Process of a Right-Side Sessile Serrated Adenoma/Polyp with Cytological Dysplasia to an Invasive Submucosal Adenocarcinoma

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Kaoru Omori ◽  
Kanako Yoshida ◽  
Sadafumi Tamiya ◽  
Tsutomu Daa ◽  
Masahiro Kan
Keyword(s):  
Narrow Band Imaging ◽  
Rapid Progression ◽  
Imaging Features ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Small Nodule ◽  
Circular Pattern ◽  
Endoscopic Observation ◽  
Submucosal Adenocarcinoma ◽  
The Right

A sessile serrated adenoma/polyp (SSA/P) with cytological dysplasia in the right colon, which transformed to an invasive submucosal adenocarcinoma finally, was endoscopically observed in a 76-year-old woman. A whitish soft SSA/P (approximately 25 mm in diameter) was detected in the cecum. Biopsy samples were obtained from the small nodule, and the lesion was eventually diagnosed as an SSA/P with cytological dysplasia, considering endoscopic observations, among which the narrow-band imaging features suggested that the lesion was adenomatous, that is, a round-oval pattern, and hyperplastic, that is, comprising a circular pattern with dots and an invisible capillary vessel. After 11 months, an SSA/P had rapidly developed into a submucosal adenocarcinoma with lymphatic infiltrations, and the most aggressive deep invasion was observed in the central depression. This case suggests that right-side SSA/Ps with cytological dysplasia should be removed immediately, considering the potential for rapid progression to a larger size and eventually to deep and extensive cancer.

Adjunctive use of chromoendoscopy may improve the diagnostic performance of narrow-band imaging for small sessile serrated adenoma/polyp

2018 ◽  
Vol 33 (2) ◽  
pp. 466-474 ◽  
Author(s):  
Li-Chun Chang ◽  
Chia-Hung Tu ◽  
Been-Ren Lin ◽  
Chia-Tung Shun ◽  
Weng-Feng Hsu ◽  
...  
Keyword(s):  
Diagnostic Performance ◽  
Narrow Band ◽  
Narrow Band Imaging ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma

scholarly journals Use of endocytoscopy for identification of sessile serrated adenoma/polyps and hyperplastic polyps by quantitative image analysis of the luminal areas

2017 ◽  
Vol 05 (08) ◽  
pp. E769-E774 ◽  
Author(s):  
Yushi Ogawa ◽  
Shin-ei Kudo ◽  
Yuichi Mori ◽  
Nobunao Ikehara ◽  
Yasuharu Maeda ◽  
...  
Keyword(s):  
Roc Analysis ◽  
Normal Mucosa ◽  
Receiver Operating Curve ◽  
Hyperplastic Polyps ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Important Indicator ◽  
Cutoff Value ◽  
Luminal Area ◽  
Magnifying Chromoendoscopy

Abstract Background and study aims Recent studies that used magnifying chromoendoscopy and endocytoscopy (EC) to investigate endoscopic features of sessile serrated adenoma/polyps (SSA/Ps) suggested that a dilated crypt opening was an important indicator of SSA/Ps. However, no studies to date have measured the actual extent of dilatation. Hence, we investigated retrospectively the luminal areas using EC to determine a cutoff value for differentiating SSA/Ps from hyperplastic polyps (HPs). Patients and methods A total of 101 lesions, including 25 SSA/Ps, 66 HPs, and 10 normal mucosal samples, assessed by an integrated-type EC were collected. For each lesion, 1 image that showed the widest lumen was selected and the average area of the contiguous 3 lumens were calculated. The cutoff value differentiating SSAPs from HPs was determined by receiver operating curve (ROC) analysis. Results The mean luminal areas of SSA/Ps and HPs were 4152 μm2 and 2117 μm2, respectively. ROC analysis found that a luminal area cutoff of 3068 μm2 had a sensitivity of 80.0 %, a specificity of 77.3 %, an accuracy of 78.0 %, and an area under the ROC curve of 0.865. Furthermore, a cutoff of ≥ 556 μm2 was found to accurately distinguish between HPs and normal mucosa (sensitivity 98.5 %, specificity 100 %, accuracy 98.7 %, and AUC 0.998). Conclusions EC analysis of the luminal area is useful for differentiating between SSAPs and HPs. This approach could be adapted for computer-aided diagnosis of SSA/P.

scholarly journals Sessile serrated adenoma of the appendix: literature review and clinical cases

2020 ◽  
Vol 1 (10) ◽  
pp. 105-109
Author(s):  
L. M. Mikhaleva ◽  
R. A. Vandysheva ◽  
I. S. Kozlov ◽  
O. A. Vasyukova ◽  
K. Yu. Midiber ◽  
...  
Keyword(s):  
Literature Review ◽  
Clinical Symptoms ◽  
Health Department ◽  
Endoscopic Examination ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
True Incidence ◽  
Moscow City ◽  
Serrated Adenomas ◽  
Clinical Cases

The article contains a literature review of clinical cases describing sessile serrated adenomas in the appendix from 1998 to 2018. Currently, it is still diffi cult to assess the true incidence of this pathology due to the fact that in most cases serrated adenomas are accidental fi ndings diagnosed after removing an inflamed appendix, since often, at small sizes, they do not cause clinical symptoms, do not bother patients and are inaccessible for endoscopic examination (if located behind its orifi ce). In addition, we present 2 clinical cases of sessile serrated adenoma of the appendix in patients who were admitted to the City Clinical Hospital No. 31 of the Moscow City Health Department in 2018 due to acute appendicitis, with a clinical and morphological characteristic, including a molecular genetics study.

scholarly journals 136 Usefulness of Magnifying Narrow-Band Imaging Endoscopy for the Diagnosis of Sessile Serrated Adenoma/Polyp With Dysplasia/Carcinoma

2019 ◽  
Vol 114 (1) ◽  
pp. S80-S80
Author(s):  
Takashi Murakami ◽  
Naoto Sakamoto ◽  
Hirofumi Fukushima ◽  
Hiroya Ueyama ◽  
Tomoyoshi Shibuya ◽  
...  
Keyword(s):  
Narrow Band ◽  
Narrow Band Imaging ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma
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