scholarly journals Influence of SPK with Enteric Drainage on the Pancreatic Exocrine Function in Diabetic Patients with Uremia

2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Guanghui Pei ◽  
Wu Lv ◽  
Xiaohang Li ◽  
Guoqing Zhang ◽  
Jialin Zhang
Keyword(s):  
Exocrine Function ◽  
Diabetic Patients ◽  
Fecal Elastase ◽  
Enteric Drainage ◽  
Pancreatic Exocrine ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Fecal Pancreatic Elastase ◽  
Elastase Level ◽  
Simultaneous Pancreas Kidney Transplantation

Objective. This study aimed to determine the use of fecal elastase in evaluating the effect of simultaneous pancreas–kidney transplantation with enteric drainage on the pancreatic exocrine function of diabetic patients with uremia.Methods. A total of 19 patients with simultaneous pancreas–kidney transplantation (SPK) with enteric drainage, 31 diabetic patients with uremia (chronic renal failure (CRF)), 22 diabetic patients with uremia who underwent renal transplantation (RT), and 20 normal individuals (CON) were included in the study. Pancreatic exocrine insufficiency was determined using fecal elastase. Results. The fecal pancreatic elastase level in SPK patients with enteric drainage was 479 μg/g, which was significantly higher than 229 μg/g in CRF patients and 197 μg/g in RT patients. Using 200 μg/g as the established threshold, a reduced fecal pancreatic elastase level was found in 14/31 of CRF patients, 12/22 of RT patients, 1/19 of SPK patients with enteric drainage, and 1/20 of CON patients. The correlation analysis revealed a significant association between fecal elastase and glycosylated hemoglobin.Conclusions. The present study indicated that SPK with enteric drainage improves pancreatic endocrine and exocrine functions. Fecal elastase may be a clinically relevant means to determine the therapeutic effects.

Elevated MBL levels in type 1 diabetic patients are reversed after simultaneous pancreas–kidney transplantation

2014 ◽  
Vol 31 (4) ◽  
pp. 226
Author(s):  
Pieter van der Pol ◽  
Danielle J. van Gijlswijk-Jansen ◽  
Roel Bijkerk ◽  
Eelco J.P. de Koning ◽  
Johan W. de Fijter ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Diabetic Patients ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Type 1 Diabetic Patients ◽  
Simultaneous Pancreas Kidney Transplantation

scholarly journals Beware the band adhesion: an unexpected cause of double obstruction following intraperitoneal kidney transplantation

2020 ◽  
Vol 2020 (8) ◽  
Author(s):  
David Tovmassian ◽  
Linda Tang ◽  
Ahmer M Hameed ◽  
Jinna Yao ◽  
Peter Daechul Yoon ◽  
...  
Keyword(s):  
Small Intestine ◽  
Kidney Transplantation ◽  
Internal Herniation ◽  
Transplant Patients ◽  
Boari Flap ◽  
Enteric Drainage ◽  
Kidney Transplant Patients ◽  
Pancreas Kidney Transplantation ◽  
Simultaneous Pancreas Kidney ◽  
Simultaneous Pancreas Kidney Transplantation

Abstract Small bowel obstruction (SBO) following intraperitoneal renal transplantation, either solitary or due to simultaneous pancreas-kidney transplantation, is a known complication. While SBO is most commonly due to adhesions, there have been documented cases of internal herniation following simultaneous pancreas-kidney transplantation with enteric drainage due to the formation of a mesenteric defect. We present a unique complication in which the transplant ureter has caused strangulation and necrosis of a length of small intestine. The transplant ureter was mistaken for a band adhesion and divided. Post-operative anuria signalled this difficult diagnosis. Subsequent re-look laparotomy and ureteric reimplantation with Boari flap were required. Therefore, it is important to consider the ureter as a cause of internal herniation in kidney transplant patients and recognize that a band adhesion within the pelvis may in fact be the transplant ureter, obstructing a loop of small intestine beneath its course.

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